Journal Information
Vol. 16. Issue 6.
Pages 486-491 (January 2005)
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Vol. 16. Issue 6.
Pages 486-491 (January 2005)
Analysis of the influence of the variable size on the characteristics and behavior of meningiomas
Análisis de la influencia de la variable tamaño en las características y comportamiento de los meningiomas
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1563
L. Mascarenhas
, H. Romão, M. Resende, A. Rocha Vaz
Neurosurgery Service. Pedro Hispano Hospital. Matosinhos. Portugal
M. Fonseca*, M. Honavar**
* Mathematics Department. Sciences and Technology Faculty. Lisbon New University. Almada. Portugal
** Anatomic Pathology Service. Pedro Hispano Hospital. Matosinhos. Portugal
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Summary

Seventy-two patients submitted to meningioma surgery at Pedro Hispano Hospital from 1997 to 2001 were reviewed to analyze the association between size (largest diameter of the lesion obtained from imaging examinations) and other variables regarding the biological behavior and clinical outcome of these patients. Statistically significant associations were found between tumor size and location, type of first symptom, type of physical examination, histological grade, surgical complications, postoperative CSF bursae and the need for blood transfusion. Patient's age, gender, duration of first symptom, clinical status at discharge and persistent complaints were not associated to tumor size. There was a trend towards a statistically significant association between tumor size and both grade of resection and persistent deficits. The causes and implications of the findings are discussed. Tumor size is a parameter that may interfere with the neurosurgeon's capacity to treat these patients as well as with their recovery.

Key words:
Meningioma
Size
Characteristics
Behavior
Correlation
Abbreviations:
CSF
LCR
WHO
Resumen

Se han revisado setenta y dos enfermos sometidos a cirugía de meningioma en el Hospital Pedro Hispano entre 1997 y 2001, para evaluar la asociación entre el tamaño (mayor diámetro de la lesión obtenido a partir de los exámenes de imagen) y otras variables concernientes a la caracterización y comportamiento de la lesión. Se han encontrado asociaciones, con significación estadística, con la localización, tipo de primer síntoma, tipo de examen físico, grado histológico, aparición de complicaciones, bolsas de LCR y transfusiones de sangre. La edad, el sexo, la duración de primer síntoma, el estado al alta hospitalaria y los síntomas persistentes no se relacionan con el tamaño. Se encontró alguna relación con el tipo de exéresis y señales persistentes. Se discuten las causas e implicaciones de los hallazgos. El tamaño es un parámetro que puede interferir en la capacidad del neurocirujano para tratar estos pacientes y en la capacidad de recuperación de los mismos.”

Palabras clave:
Meningioma
Tamaño
Características
Comportamiento
Correlación

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