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Vol. 18. Issue 6.
Pages 496-504 (January 2007)
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Vol. 18. Issue 6.
Pages 496-504 (January 2007)
Tumor fibroso solitario meníngeo: descripción de tres casos y revisión de la literatura
Solitary fibrous tumors of the meninges: report of three cases and literature review
J.M. Saceda-Gutiérrez
, A.J. Isla-Guerrero, C. Pérez-López, R. Ortega-Martínez, A. Gómez de la Riva, M.L. Gandia-González
Servicios Neurocirugía. Hospital Universitario La Paz. Madrid
M. Gutiérrez-Molina*, J.A. Rey-Herranz**
* Servicios Anatomía Patológica. Hospital Universitario La Paz. Madrid
** Servicios Biología Molecular. Hospital Universitario La Paz. Madrid
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Resumen

Presentamos 3 pacientes con tumor fibroso solitario de localización meníngea donde describimos el estudio histológico, así como la evolución después del tratamiento quirúrgico. Los pacientes descritos tenían edades de 37, 52 y 65 años y tras la resección total no se ha objetivado signo de recidiva en ningún caso después de 4, 6 y 7 años de seguimiento respectivamente.

Revisando la literatura se trata de un tumor indistinguible clínica y radiológicamente del meningioma típico, haciendo necesario el uso de pruebas inmunohistoquímicas para realizar el diagnóstico diferencial, donde la positividad para el CD34 y la negatividad para el EMA definen al tumor fibroso solitario. Se trata de un tumor benigno, en el que la resección total es el principal factor pronóstico; no obstante, se han descrito casos de recidivas locales y metástasis a distancia. Todas estas características las encontramos en los casos presentados en el presente trabajo, quedando la incertidumbre de su capacidad de recidiva local o sistémica en el futuro.

Palabras clave:
Tumores de sistema nervioso central
Tumores meníngeos
Tumor fibroso solitario
Neoplasias células fusiformes
CD34
Abreviaturas:
EMA
HPC
TC
TFS
RM
Summary

We report 3 patients with fibrous solitary tumor of meningeal location where we described the histological study, as well as evolution after the surgical treatment. The described patients presented ages of 37, 52 and 65 years, after the resection has not appeared an objective sign of recurrence in any case after 4, 6 and 7 years of follow-up respectively.

Checking the literature the tumor is indistinguishable clinical and radiolocally of the typical meningioma, doing necessary the use of inmunohistochemistry to do the differential diagnosis, where positiveness for CD34 and the negativeness for EMA define the fibrous solitary tumor. It is about a benign tumor, where total removing is the principal factor in prognosis, nevertheless there are cases of local recurrences and long-distance metastasis. We can find all these characteristics in the showed cases of the present article, having the uncertainty of its local or systemic relapse ability in the future.

Key words:
Central nervous system tumors
Meningeal tumors
Solitary fibrous tumor
Spindle cell neoplasm
CD34

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