A 57-year-old male woodworker was diagnosed with T3N0M0 intestinal-type nasal adenocarcinoma in 2021. He underwent endoscopic craniofacial resection and radiotherapy, with no recurrence for three years. In 2024, he presented with occipital headache and vomiting, revealing a frontal necrotic-hemorrhagic lesion with acute hydrocephalus, initially suspected to be a brain abscess. However, a history of cocaine use suggested brain necrosis facilitated by prior surgery. This unique case demonstrates brain necrosis directly attributable to intranasal cocaine use. Surgeons should consider substance use as a contributing factor in postoperative complications after skull base surgery.
Un varón de 57 años, carpintero de oficio, se diagnosticó en 2021 con adenocarcinoma nasal tipo intestinal T3N0M0. Se sometió a una resección craneofacial endoscópica y a radioterapia, sin evidencia de recurrencia durante tres años. En 2024, presentó cefalea occipital y vómitos, revelando en las pruebas de imagen una lesión frontal necrótica-hemorrágica con hidrocefalia aguda, inicialmente considerada un absceso cerebral. Sin embargo, los antecedentes de consumo de cocaína sugirieron necrosis cerebral por el uso de este tóxico con vía de acceso directo secundaria a los antecedentes quirúrgicos. Este caso único demuestra necrosis cerebral directamente atribuible al uso de cocaína intranasal. Los cirujanos deben considerar el consumo de sustancias como un factor contribuyente en las complicaciones posoperatorias tras una cirugía de base de cráneo.
Article

If it is the first time you have accessed you can obtain your credentials by contacting Elsevier Spain in suscripciones@elsevier.com or by calling our Customer Service at902 88 87 40 if you are calling from Spain or at +34 932 418 800 (from 9 to 18h., GMT + 1) if you are calling outside of Spain.
If you already have your login data, please click here . p>
If you have forgotten your password you can you can recover it by clicking here and selecting the option ¿I have forgotten my password¿.



