array:23 [
  "pii" => "S1130147399709814"
  "issn" => "11301473"
  "doi" => "10.1016/S1130-1473(99)70981-4"
  "estado" => "S300"
  "fechaPublicacion" => "1999-01-01"
  "aid" => "70981"
  "copyright" => "Sociedad Española de Neurocirugía"
  "copyrightAnyo" => "1999"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Neurocirugia. 1999;10:158-60"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 3074
    "formatos" => array:3 [
      "EPUB" => 15
      "HTML" => 1544
      "PDF" => 1515
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1130147399709826"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(99)70982-6"
    "estado" => "S300"
    "fechaPublicacion" => "1999-01-01"
    "aid" => "70982"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Neurocirugia. 1999;10:164"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1897
      "formatos" => array:3 [
        "EPUB" => 15
        "HTML" => 777
        "PDF" => 1105
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Migración bilateral de catéter ventriculoperitoneal a bolsa escrotal"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:4 [
        0 => array:1 [
          "paginaInicial" => "164"
        ]
        1 => array:1 [
          "paginaInicial" => "166"
        ]
        2 => array:1 [
          "paginaInicial" => "168"
        ]
        3 => array:1 [
          "paginaInicial" => "170"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Bilateral scrotal migration of a ventriculoperitoneal shunt"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "L.F. Porras Estrada, I. Fernández Portales, J.M. Cabezudo Artero, J.A. Rodríguez-Sánchez, L. Lorenzana Honrado"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "L.F."
              "apellidos" => "Porras Estrada"
            ]
            1 => array:2 [
              "nombre" => "I."
              "apellidos" => "Fernández Portales"
            ]
            2 => array:2 [
              "nombre" => "J.M."
              "apellidos" => "Cabezudo Artero"
            ]
            3 => array:2 [
              "nombre" => "J.A."
              "apellidos" => "Rodríguez-Sánchez"
            ]
            4 => array:2 [
              "nombre" => "L."
              "apellidos" => "Lorenzana Honrado"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "Fernández Vigo"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Fernández"
              "apellidos" => "Vigo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399709826?idApp=UINPBA00004B"
    "url" => "/11301473/0000001000000002/v1_201305151007/S1130147399709826/v1_201305151007/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1130147399709802"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(99)70980-2"
    "estado" => "S300"
    "fechaPublicacion" => "1999-01-01"
    "aid" => "70980"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Neurocirugia. 1999;10:156"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2000
      "formatos" => array:3 [
        "EPUB" => 14
        "HTML" => 1080
        "PDF" => 906
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Comentarios al artículo"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "156"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "L. González Feria"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "L."
              "apellidos" => "González Feria"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399709802?idApp=UINPBA00004B"
    "url" => "/11301473/0000001000000002/v1_201305151007/S1130147399709802/v1_201305151007/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Cordoma condroide&#58; Presentaci&#243;n de <span class="elsevierStyleBold">un</span> caso con caracter&#237;sticas inmunohistoqu&#237;micas peculiares"
    "tieneTextoCompleto" => 0
    "paginas" => array:2 [
      0 => array:2 [
        "paginaInicial" => "158"
        "paginaFinal" => "160"
      ]
      1 => array:1 [
        "paginaInicial" => "162"
      ]
    ]
    "autores" => array:2 [
      0 => array:3 [
        "autoresLista" => "R&#46; L&#225;zaro Santander, J&#46;M&#46; Vera Rom&#225;n"
        "autores" => array:2 [
          0 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "L&#225;zaro Santander"
          ]
          1 => array:2 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Vera Rom&#225;n"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Anatom&#237;a Patol&#243;gica&#46; Hospital General de Castell&#243;n&#46; Castell&#243;n"
          ]
        ]
      ]
      1 => array:3 [
        "autoresLista" => "J&#46;A&#46; Barcia Albacar, J&#46;L&#46; Gil Sal&#250;, J&#46;M&#46; Gonz&#225;lez Darder"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "J&#46;A&#46;"
            "apellidos" => "Barcia Albacar"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "J&#46;L&#46;"
            "apellidos" => "Gil Sal&#250;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Gonz&#225;lez Darder"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Secci&#243;n de Neurocirug&#237;a&#46; Hospital General de Castell&#243;n&#46; Castell&#243;n"
            "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
            "identificador" => "aff0010"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Chondroid chordoma&#58; a case report with unusual inmunohistochemical features"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec156668"
          "palabras" => array:4 [
            0 => "Cordoma condroide"
            1 => "Cordoma"
            2 => "Condrosarcoma"
            3 => "Tumores base cr&#225;neo"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec156667"
          "palabras" => array:4 [
            0 => "Chondroid chordoma"
            1 => "Chordoma"
            2 => "Chondrosarcoma"
            3 => "Skull base tumors"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentarnos el caso de una mujer de 68 a&#241;os con un cordoma condroide del pe&#241;asco derecho que se extend&#237;a extracranealmente por el agujero rasgado posterior&#46; Inmunohistoqu&#237;micamente mostraba un perfil peculiar con positividad para vimentina&#44; prote&#237;na S100&#44; queratinas &#40;AEl-AE3&#41; y CEA&#44; siendo negativo para EMA&#44; fenotipo no descrito hasta ahora&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El cordoma condroide no est&#225; reconocido corno una entidad definida por todos los autores&#46; Tiene rasgos morfol&#243;gicos de cordoma y condrosarcoma&#44; lo que se corrobora por su inmunofenotipia inmunohistoqu&#237;mica&#44; que es la de esos dos tipos de tumor&#46; Ocurre mayormente en la base del cr&#225;neo&#44; pero tambi&#233;n en la regi&#243;n sacrocox&#237;gea&#46; Parece tener una mejor evoluci&#243;n que los cordomas convencionales&#44; aunque el n&#250;mero de casos recogido en la literatura es todav&#237;a insuficiente para asegurarlo&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We present a case of chondroid chordoma involving the petrous bone&#44; with an extracranial extension through the yugular foramen in a 68 year-old woman&#46; Immunohistochemical staining exhibited a positive reaction for vimentin&#44; S-100 protein&#44; keratin &#40;AEl-AE3&#41; and CEA&#44; but lacked reactivity for EMA&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A chondroid chordoma is not an entity universally recognized&#46; It has both the morfological features of chordoma and chondrosarcoma&#46; This is also shown by its inmunohistochemical profile because shares the positivity of both tumors&#46; Although mainly found at the cranium base it can also be found at the sacro-coccygeal region&#46; It appears to have better prognosis than conventional chordoma but since there have been recorded too few cases it cannot be substantiated as yet&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">L&#225;zaro Santander&#44; R&#59; Vera Rom&#225;n&#44; J&#46;M&#46;&#59; Barcia Albacar&#44; lA&#46;&#59; Gil Sal&#250;&#44; J&#46;L&#46;&#59; Gonz&#225;lez Darder&#44; J&#46;M&#46;&#58; Cordoma condroide&#58; Presentaci&#243;n de un caso con caracter&#237;sticas inmunohistoqu&#237;micas peculiares&#46; Neurocirug&#237;a 1999&#59; 10&#58; 158&#8211;162&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:20 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordomas and cartilaginous tumors at the skull base"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;J&#46; Heffelfinger"
                            1 => "D&#46;C&#46; Dahlin"
                            2 => "C&#46;S&#46; Mac Carthy"
                            3 => "J&#46;W&#46; Beabout"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1973"
                        "volumen" => "32"
                        "paginaInicial" => "410"
                        "paginaFinal" => "420"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4722921"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Demonstration of cytokeratins and epithelial membrana antigen in chordoid chordoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;R&#46; Salisbury"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/path.1711530106"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Pathol"
                        "fecha" => "1987"
                        "volumen" => "153"
                        "paginaInicial" => "37"
                        "paginaFinal" => "40"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2444686"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordoma&#58; an inmunohistochemical study of 20 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Meis"
                            1 => "A&#46;A&#46; Giraldo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Pathol Lab Med"
                        "fecha" => "1988"
                        "volumen" => "112"
                        "paginaInicial" => "553"
                        "paginaFinal" => "556"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2451900"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordoma and chondroid neoplasms of the spheno-occiput&#58; an inmunohistochemical study of 41 cases with prognostic and nosologic implications"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "A&#46; Mitchell"
                            1 => "B&#46;W&#46; Scheithauer"
                            2 => "K&#46;K&#46; Unni"
                            3 => "P&#46;J&#46; Forsyth"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1993"
                        "volumen" => "72"
                        "paginaInicial" => "2943"
                        "paginaFinal" => "2949"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7693324"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordoid chordoma&#58; a variant of chordoma&#46; A morphologic and inmunohistochemical study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;E&#46; Rosenberg"
                            1 => "G&#46;A&#46; Brown"
                            2 => "A&#46;K&#46; Bhan"
                            3 => "J&#46;M&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J&#46; Clin Pathol"
                        "fecha" => "1994"
                        "volumen" => "101"
                        "paginaInicial" => "36"
                        "paginaFinal" => "41"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7506477"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Does chondroid chordoma exist&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;J&#46; Brooks"
                            1 => "V&#46; Livolsi"
                            2 => "J&#46;A&#46; Trojanowski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Neuropathol"
                        "fecha" => "1987"
                        "volumen" => "72"
                        "paginaInicial" => "229"
                        "paginaFinal" => "235"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2436434"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chondrosarcoma of the temporal bone&#46; Diagnosis and treatment of 13 cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Coltrera"
                            1 => "P&#46;B&#46; Googe"
                            2 => "T&#46;J&#46; Harrist"
                            3 => "V&#46;J&#46; Hyams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1986"
                        "volumen" => "58"
                        "paginaInicial" => "2689"
                        "paginaFinal" => "2696"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3022910"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intracranial chordomas&#58; a clinicopathological and prognostic study of 51 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "P&#46;A&#46; Forsyth"
                            1 => "T&#46;L&#46; Cascino"
                            2 => "E&#46;G&#46; Shaw"
                            3 => "B&#46;W&#46; Scheithauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1993.78.5.0741"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1993"
                        "volumen" => "78"
                        "paginaInicial" => "741"
                        "paginaFinal" => "747"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8468605"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Extracranial skull base chondrosarcoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Sidman"
                            1 => "R&#46;D&#46; Nichols"
                            2 => "U&#46;B&#46; Raju"
                            3 => "B&#46; Mehta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ear Nose Throat J"
                        "fecha" => "1989"
                        "volumen" => "68"
                        "paginaInicial" => "626"
                        "paginaFinal" => "632"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2684602"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordomas and chondrosarcomas of the cranial base&#58; results and follow-up of 60 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "E&#46; Gay"
                            1 => "L&#46;N&#46; Sekhar"
                            2 => "E&#46; Rubinstein"
                            3 => "D&#46;C&#46; Wright"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1995"
                        "volumen" => "36"
                        "paginaInicial" => "887"
                        "paginaFinal" => "897"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7791978"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chordoma&#58; an inmunohistologic study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Abenoza"
                            1 => "R&#46;K&#46; Sibley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Pathol"
                        "fecha" => "1986"
                        "volumen" => "17"
                        "paginaInicial" => "744"
                        "paginaFinal" => "747"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2424820"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inmunohistochemical distinction of classic and chondroid chordomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;P&#46; Walker"
                            1 => "S&#46;K&#46; Landas"
                            2 => "C&#46;M&#46; Bromley"
                            3 => "M&#46;T&#46; Sturm"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Mod Pathol"
                        "fecha" => "1991"
                        "volumen" => "4"
                        "paginaInicial" => "661"
                        "paginaFinal" => "666"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1722044"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chondroid chordoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;W&#46; Mierau"
                            1 => "D&#46;A&#46; Weeks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ultrastruct Pathol"
                        "fecha" => "1987"
                        "volumen" => "11"
                        "paginaInicial" => "731"
                        "paginaFinal" => "737"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3686707"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tissue polipeptide antigen staining of the chordoma and notochordal remnants"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;C&#46; Burger"
                            1 => "M&#46; Makek"
                            2 => "P&#46; Kleihues"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Neuropathol"
                        "fecha" => "1986"
                        "volumen" => "70"
                        "paginaInicial" => "269"
                        "paginaFinal" => "272"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2429493"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Classical and chondroid chordoma a light-microscopic&#44; histochemical&#44; ultrastructural and inmunohistochemical analysis of the various cell"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Persson"
                            1 => "L&#46;G&#46; Kindblom"
                            2 => "L&#46; Angervall"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0344-0338(11)80579-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pathol Res Pract"
                        "fecha" => "1991"
                        "volumen" => "187"
                        "paginaInicial" => "828"
                        "paginaFinal" => "838"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1754509"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chondroid chordomas and lowgrade chondrosarcomas of 17 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;L&#46; Wojno"
                            1 => "R&#46;H&#46; Hruban"
                            2 => "P&#46; Gar&#237;n-Chesa"
                            3 => "A&#46;G&#46; Huvos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1992"
                        "volumen" => "16"
                        "paginaInicial" => "1144"
                        "paginaFinal" => "1152"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1463093"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chondroid chordoma&#46; A hyalinized chordoma without cartilaginous differentiation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;B&#46; Jeffrey"
                            1 => "C&#46;G&#46; Biava"
                            2 => "R&#46;L&#46; Davis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Pathol"
                        "fecha" => "1995"
                        "volumen" => "103"
                        "paginaInicial" => "271"
                        "paginaFinal" => "279"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7532910"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Probable causes of recurrence in patients with chordoma and chondrosarcoma of the base of skull and cervical spine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;P&#46; Austin"
                            1 => "M&#46;M&#46; Urie"
                            2 => "G&#46; Cardenosa"
                            3 => "J&#46;E&#46; Munzenrider"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Radiat Oncol Biol Phys"
                        "fecha" => "1993"
                        "volumen" => "25"
                        "paginaInicial" => "439"
                        "paginaFinal" => "444"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8436522"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chondroid chordoma&#58; case report and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46; Watson"
                            1 => "D&#46;R&#46; Smith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Indiana Med"
                        "fecha" => "1991"
                        "volumen" => "84"
                        "paginaInicial" => "18"
                        "paginaFinal" => "21"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1997598"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Base of skull chordoma&#58; a correlative study of histologic and clinical features of 62 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:4 [
                            0 => "J&#46;X&#46; O&#39;Connell"
                            1 => "L&#46;G&#46; Renard"
                            2 => "N&#46;J&#46; Liebsch"
                            3 => "J&#46;T&#46; Efird"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1994"
                        "volumen" => "74"
                        "paginaInicial" => "2261"
                        "paginaFinal" => "2267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7922977"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/11301473/0000001000000002/v1_201305151007/S1130147399709814/v1_201305151007/es/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/11301473/0000001000000002/v1_201305151007/S1130147399709814/v1_201305151007/es/main.pdf?idApp=UINPBA00004B&text.app=https://revistaneurocirugia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399709814?idApp=UINPBA00004B"
]
Compartir
Información de la revista
Vol. 10. Núm. 2.
Páginas 158-160 (enero 1998)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 10. Núm. 2.
Páginas 158-160 (enero 1998)
Cordoma condroide: Presentación de un caso con características inmunohistoquímicas peculiares
Chondroid chordoma: a case report with unusual inmunohistochemical features
Visitas
3061
R. Lázaro Santander, J.M. Vera Román
Servicio de Anatomía Patológica. Hospital General de Castellón. Castellón
J.A. Barcia Albacar*, J.L. Gil Salú*, J.M. González Darder*
* Sección de Neurocirugía. Hospital General de Castellón. Castellón
Este artículo ha recibido
Información del artículo
Resumen

Presentarnos el caso de una mujer de 68 años con un cordoma condroide del peñasco derecho que se extendía extracranealmente por el agujero rasgado posterior. Inmunohistoquímicamente mostraba un perfil peculiar con positividad para vimentina, proteína S100, queratinas (AEl-AE3) y CEA, siendo negativo para EMA, fenotipo no descrito hasta ahora.

El cordoma condroide no está reconocido corno una entidad definida por todos los autores. Tiene rasgos morfológicos de cordoma y condrosarcoma, lo que se corrobora por su inmunofenotipia inmunohistoquímica, que es la de esos dos tipos de tumor. Ocurre mayormente en la base del cráneo, pero también en la región sacrocoxígea. Parece tener una mejor evolución que los cordomas convencionales, aunque el número de casos recogido en la literatura es todavía insuficiente para asegurarlo.

Palabras clave:
Cordoma condroide
Cordoma
Condrosarcoma
Tumores base cráneo
Summary

We present a case of chondroid chordoma involving the petrous bone, with an extracranial extension through the yugular foramen in a 68 year-old woman. Immunohistochemical staining exhibited a positive reaction for vimentin, S-100 protein, keratin (AEl-AE3) and CEA, but lacked reactivity for EMA.

A chondroid chordoma is not an entity universally recognized. It has both the morfological features of chordoma and chondrosarcoma. This is also shown by its inmunohistochemical profile because shares the positivity of both tumors. Although mainly found at the cranium base it can also be found at the sacro-coccygeal region. It appears to have better prognosis than conventional chordoma but since there have been recorded too few cases it cannot be substantiated as yet.

Key words:
Chondroid chordoma
Chordoma
Chondrosarcoma
Skull base tumors

Artículo

Opciones para acceder a los textos completos de la publicación Neurocirugía
Socio
Socio de la Sociedad Española de Neurocirugía

Si es la primera vez que accede a la web puede obtener sus claves de acceso poniéndose en contacto con Elsevier España en suscripciones@elsevier.com o a través de su teléfono de Atención al Cliente 902 88 87 40 si llama desde territorio español o del +34 932 418 800 (de 9 a 18h., GMT + 1) si lo hace desde el extranjero.

Si ya tiene sus datos de acceso, clique aquí.

Si olvidó su clave de acceso puede recuperarla clicando aquí y seleccionando la opción "He olvidado mi contraseña".

Suscriptor
Suscriptor de la revista

Si ya tiene sus datos de acceso, clique aquí.

Si olvidó su clave de acceso puede recuperarla clicando aquí y seleccionando la opción "He olvidado mi contraseña".
Suscribirse
Suscribirse a:

Neurocirugía

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 19,34 €

Comprar ahora
Contactar
Teléfono para suscripciones e incidencias
De lunes a viernes de 9h a 18h (GMT+1) excepto los meses de julio y agosto que será de 9 a 15h
Llamadas desde España
932 415 960
Llamadas desde fuera de España
+34 932 415 960
Email
Idiomas
Neurocirugía
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?