Metástasis hipofisarias como primera manifestación de cáncer orgánico. Dificultades diagnósticas
Pituitary metastases as first manifestation of systemic cancer
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Clavel" "autores" => array:1 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Clavel" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397707334?idApp=UINPBA00004B" "url" => "/11301473/0000000800000004/v1_201305151505/S1130147397707334/v1_201305151505/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Metástasis hipofisarias como primera manifestación de cáncer orgánico. Dificultades diagnósticas" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "316" "paginaFinal" => "320" ] ] "autores" => array:2 [ 0 => array:3 [ "autoresLista" => "A. Maíllo, P. Díaz, J. Hernández, I. Onzain, F. Morales" "autores" => array:5 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Maíllo" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Díaz" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Hernández" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Onzain" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "Morales" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital Universitario de Salamanca" ] ] ] 1 => array:3 [ "autoresLista" => "I. Subhi-Issa Ahmad" "autores" => array:1 [ 0 => array:3 [ "nombre" => "I." "apellidos" => "Subhi-Issa Ahmad" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Anatomía Patológica. Hospital Universitario de Salamanca" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pituitary metastases as first manifestation of systemic cancer" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec163216" "palabras" => array:3 [ 0 => "Tumores hipofisarios" 1 => "Metástasis hipofisarias" 2 => "Cirugía transesfenoidal" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec163215" "palabras" => array:3 [ 0 => "Pituitary tumors" 1 => "Hypophyseal metastatic tumor" 2 => "Transsphenoidal surgery" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Las metástasis hipofisarias constituyen una entidad poco frecuente en la patología neuroquirúrgica. Cuando se diagnostican suele ser en el entorno de un proceso de diseminación generalizado a partir de un cáncer primitivo fuera del sistema nervioso. Por el contrario suele ser más raro que se presenten como metástasis aislada. Esta rareza, unido al hecho de que el diagnóstico por imagen suele presentar dificultades, hace que se diagnostiquen en la gran mayoría de forma retrospectiva.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se describen tres pacientes con metástasis hipofisarias, en dos de los cuales este proceso fue la primera manifestación de la enfermedad, y se hacen algunas consideraciones etiopatogénicas, clínicas, diagnósticas y terapéuticas.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Pituitary metastases is a rare clinical diagnosis usually made in the setting of known primary systemic cancer with widespread metastasis to other organs. Pituitary metastases as the first manifestation of a still undiagnosed systemic cancer is much less frequent.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The cases of three patients harboring pituitary metastases are described. In two of them the pituitary tumor was the first manifestation of the systemic cancer and loss of visual acuity was the most common initial clinical sign.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Maíllo, A.; Díaz, P.; Subhi-Issa Ahmad, I.; Hernández, J.; Onzaín, l.; Morales, F: Metástasis hipofisarias como primera manifestación de cáncer orgánico. Dificultades diagnósticas. Neurocirugía 1997; 8: 316–320.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:17 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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| 2016 Julio | 25 | 35 | 60 |
| 2015 Diciembre | 2 | 0 | 2 |
| 2015 Agosto | 1 | 0 | 1 |
| 2015 Julio | 1 | 4 | 5 |
| 2015 Junio | 17 | 28 | 45 |
| 2015 Mayo | 19 | 28 | 47 |
| 2015 Abril | 11 | 28 | 39 |
| 2015 Marzo | 16 | 19 | 35 |
| 2015 Febrero | 11 | 21 | 32 |
| 2015 Enero | 11 | 27 | 38 |
| 2014 Diciembre | 12 | 25 | 37 |
| 2014 Noviembre | 9 | 37 | 46 |
| 2014 Octubre | 16 | 34 | 50 |
| 2014 Septiembre | 15 | 43 | 58 |
| 2014 Agosto | 18 | 43 | 61 |
| 2014 Julio | 13 | 22 | 35 |
| 2014 Junio | 25 | 29 | 54 |
| 2014 Mayo | 22 | 27 | 49 |
| 2014 Abril | 13 | 29 | 42 |
| 2014 Marzo | 16 | 39 | 55 |
| 2014 Febrero | 9 | 27 | 36 |
| 2014 Enero | 13 | 27 | 40 |
| 2013 Diciembre | 11 | 23 | 34 |
| 2013 Noviembre | 18 | 28 | 46 |
| 2013 Octubre | 22 | 60 | 82 |
| 2013 Septiembre | 26 | 42 | 68 |
| 2013 Agosto | 25 | 45 | 70 |
| 2013 Julio | 23 | 37 | 60 |
| 2013 Junio | 18 | 33 | 51 |
| 2013 Mayo | 12 | 30 | 42 |
| 2013 Abril | 15 | 22 | 37 |
| 2013 Marzo | 12 | 22 | 34 |
| 2013 Febrero | 14 | 22 | 36 |
| 2013 Enero | 7 | 12 | 19 |
| 2012 Diciembre | 9 | 13 | 22 |
| 2012 Noviembre | 0 | 6 | 6 |
| 2012 Octubre | 0 | 3 | 3 |
| 2012 Septiembre | 0 | 3 | 3 |
| 2012 Enero | 5 | 0 | 5 |
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