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Vol. 1. Núm. 1.
Páginas 11-15 (enero 1990)
Estudio cinético de tumores cerebrales humanos
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B. Conde Guerri, F. Comuñas González, E. Sinués Porta, M. Arrazola Schlamilch, V. Calatayud Maldonado
Departamento de Ciencias Morfológicás. Facultad de Medicina de Zaragoza. Servicio de Neurocirugía. Hospital Clínico Universitario de Zaragoza
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Efectuamos un estudio sobre 11 tumores intracerebrales malignos con objeto de evaluar, in vivo, la cinética celular de los mismos. La incorporación de H-TdR y su detección mediante autoradiografía nos proporciona el índice de marcado celular y la capacidad proliferativa tumoral. Describimos los hallazgos autoradiográficos y las características de marcado celular. Asimismo, este trabajo establece una correlación entre estos parámetros cinéticos y la supervivencia de los pacientes.

Palabras clave:
Tumores cerebrales humanos
Cinética celular
Indice de marcado
Autoradiografía
Summary

Eleven patients with various brain tumors received H-TdR at the time of craniotomy. Biopsied materials were fixed and sectioned. Autoradiographic methods were used to evaluate the label index (LI) of the tumors and the characteristics of the autoradiographic label. Our study retlects the cellular kinetic of human tumors in situ.

Key words:
Brain tumors
Autoradiography
Cell kinetics

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