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Vol. 4. Núm. 3.
Páginas 183-190 (enero 1992)
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Vol. 4. Núm. 3.
Páginas 183-190 (enero 1992)
Estudio experimental de la inducción ósea mediante implantes de duramadre humana pretratada en defectos craneales
Visitas
1875
J. Ravina Cabrera, L. González Feria, L. Díaz-Flores, A. Alareó Hernández, R. Gutiérrez García, F. Valladares Parrilla
Hospital Universitario de Canarias (Tenerife). Facultad de Medicina. Universidad de la Laguna
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Resumen

Se ha realizado un estudio experimental en la rata para averiguar el comportamiento de las plastias realizadas con Duramadre Humana Pretratada (D.H.P.). Se eligió como animal de experimentación la rata albina Sprague-Dawley, empleándose 90 ratas distribuidas en tres series. En la primera se implantó la D.H.P. en 40 ratas con defecto cráneo-dural, observándose la aparición, en la misma, de fenómenos de calcificación y neoformación de tejido óseo. En la segunda se implantó la D.H.P. en 30 ratas en el músculo estriado de la pared abdominal, observándose en la misma fenómenos de calcificación distrófica sin osificación. La tercera serie de 20 ratas se usó como control, provocándose un defecto cráneo-dural sin implantación de D.H.P., en esta serie se observó únicamente la presencia de tejido fibroso cicatricial, sin calcificación ni osificación. Se supone que existen en la D.H.P. factores inductores de la osteogénesis con especificidad territorial.

Summary

The authors have studied the assimilation of pretreated human duramater (P.H.D.) grafts. Ninety Sprague-Dawley albin rats were selected as experimental animals. In the first series (40 rats) P.H.D. grafts were implanted in a previously drilled cranial defecto Calcification and bone tissue neoformation was observed. In the second series (30 rats) the grafs were implanted in the muscles of the abdomen. Dystrophic calcification without ossification was observed in this group. The third series (20 rats) were used as control group. Simple cranial defect was done without implantation of P.H.D. and only scar tissue without calcification or ossification was observed. It seems that P.H.D. grafts have osteogenic potential with local specificity factors.

Key Words:
Bone induction
Duramater
Dural graft
Osteogenesis
Experimental surgery
Palabras Clave:
Inducción ósea
Duramadre
Osteogénesis
Cirugía experimental
Plastia dural

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