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                    0 => array:2 [
                      "titulo" => "Meningeal meningematosis in a child&#58; case reporto"
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                            2 => "W&#46;F&#46; Symmans"
                            3 => "A&#46;P&#46; Gold"
                            4 => "P&#46; Carmel"
                            5 => "J&#46;M&#46; Powers"
                          ]
                        ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin&#46; Neuropathol&#46;"
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                        "numero" => "2"
                        "paginaInicial" => "82"
                        "paginaFinal" => "87"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8205731"
                            "web" => "Medline"
                          ]
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                  ]
                ]
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                    0 => array:2 [
                      "titulo" => "Neurologic diseases due to alterations in oncogenes and tumor suppressing &#40;genes&#41;"
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                            1 => "J&#46;A&#46; Rey"
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                        "tituloSerie" => "Neurolog&#237;a"
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                        "numero" => "1"
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                        "paginaFinal" => "31"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8838556"
                            "web" => "Medline"
                          ]
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                ]
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                    0 => array:2 [
                      "titulo" => "Fractional radiotherapy of small inoperable lesions of the brain using a non invasive stereotactic frame"
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                          "autores" => array:3 [
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                            2 => "J&#46; Bonnett"
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                        ]
                      ]
                    ]
                  ]
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                        "tituloSerie" => "Int&#46; J&#46; Radiat&#46; Oncol&#46; Biol&#46; Phys&#46;"
                        "fecha" => "1991"
                        "volumen" => "21"
                        "paginaInicial" => "749"
                        "paginaFinal" => "755"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1869468"
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                      "titulo" => "Meningiomas de comportamiento agresivo"
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                            3 => "J&#46; Hern&#225;ndez"
                            4 => "I&#46; G&#243;mez-Moreta"
                            5 => "A&#46; Onzain"
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                        "tituloSerie" => "Neurocirug&#237;a"
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                        "paginaInicial" => "115"
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              ]
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                    0 => array:2 [
                      "titulo" => "Meningiomas del ventr&#237;culo lateral&#46; Presentaci&#243;n de siete casos"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J&#46; Dom&#237;nguez"
                            1 => "R&#46; D&#237;ez Lobato"
                            2 => "J&#46; Rivas"
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                        ]
                      ]
                    ]
                  ]
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                        "tituloSerie" => "Neurocirug&#237;a"
                        "fecha" => "1990"
                        "volumen" => "1"
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                        "paginaFinal" => "365"
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                    ]
                  ]
                ]
              ]
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                      "titulo" => "Metastasis in meningioma"
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                            0 => "S&#46;A&#46; Enam"
                            1 => "S&#46; Abdulrauf"
                            2 => "B&#46; Mehta"
                            3 => "G&#46;M&#46; Malik"
                            4 => "A&#46; Mahmood"
                          ]
                        ]
                      ]
                    ]
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                        "tituloSerie" => "Acta Neurochir&#46; &#40;Wien&#41;"
                        "fecha" => "1996"
                        "volumen" => "138"
                        "numero" => "10"
                        "paginaInicial" => "1172"
                        "paginaFinal" => "1177"
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                      "titulo" => "Radiosurgery of acoustic neurinomas"
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                            2 => "R&#46;J&#46; Coffey"
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                        "paginaFinal" => "353"
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                            0 => "J&#46;E&#46; Hodes"
                            1 => "M&#46; Sanders"
                            2 => "P&#46; Patel"
                            3 => "R&#46;A&#46; Patchell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Stereotact Funct Neurosurg"
                        "fecha" => "1996"
                        "volumen" => "66"
                        "numero" => "1&#8211;3"
                        "paginaInicial" => "15"
                        "paginaFinal" => "18"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8938927"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Meningioma with malignant transformation and implantation in the subarachnoid space"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;T&#46; Hoffmann"
                            1 => "K&#46;M&#46; Earle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1960"
                        "numero" => "17"
                        "paginaInicial" => "486"
                        "paginaFinal" => "492"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Progesterone and estrogen receptors in meningiomas&#58; prognostic considerations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;W&#46; Hsu"
                            1 => "J&#46;T&#46; Efird"
                            2 => "E&#46;T&#46; Hedley-Whyte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1997.86.1.0113"
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1997"
                        "volumen" => "86"
                        "numero" => "1"
                        "paginaInicial" => "113"
                        "paginaFinal" => "120"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8988089"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunohistochemical detection of schwannommin and neurofibromin in vestibular schwannomas&#44; ependymomas and meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;P&#46; Huynh"
                            1 => "V&#46; Mautner"
                            2 => "M&#46;E&#46; Baser"
                            3 => "D&#46; Stavrou"
                            4 => "S&#46;M&#46; Pulst"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neuropathol&#46; Exp&#46; Neurol&#46;"
                        "fecha" => "1997"
                        "volumen" => "56"
                        "numero" => "4"
                        "paginaInicial" => "382"
                        "paginaFinal" => "390"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9100669"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Brain tumor and pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Isla"
                            1 => "F&#46; Alvarez"
                            2 => "A&#46; Gonz&#225;lez"
                            3 => "A&#46; Garc&#237;a-Grande"
                            4 => "M&#46; P&#233;rez-Alvarez"
                            5 => "M&#46; Garc&#237;a-Bl&#225;zquez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Obstet&#46; Gynecol&#46;"
                        "fecha" => "1997"
                        "volumen" => "89"
                        "numero" => "1"
                        "paginaInicial" => "19"
                        "paginaFinal" => "23"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8990430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Meningiomatosis cranii in childhood&#58; a case reporto Pediatr"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;C&#46; Johnson"
                            1 => "J&#46;M&#46; Odell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurg&#46;"
                        "fecha" => "1995"
                        "volumen" => "23"
                        "numero" => "5"
                        "paginaInicial" => "273"
                        "paginaFinal" => "278"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The treatment of recurrent unresectable and malignant meningiomas with interferon alpha-2B"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46;E&#46; Kaba"
                            1 => "F&#46; De Monte"
                            2 => "J&#46;M&#46; Bruner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1997"
                        "volumen" => "40"
                        "numero" => "2"
                        "paginaInicial" => "271"
                        "paginaFinal" => "275"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9007858"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stereotactic radiosurgery of meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46; Kondziolka"
                            1 => "L&#46;D&#46; Lunsford"
                            2 => "R&#46;J&#46; Coffey"
                            3 => "J&#46;C&#46; Flickinger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1991.74.4.0552"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1991"
                        "volumen" => "74"
                        "paginaInicial" => "552"
                        "paginaFinal" => "559"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2002367"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The characteristics of the histological structure of parasagital meningiomas and their effect on postoperative recurrence"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;G&#46; Korshunov"
                            1 => "V&#46;V&#46; Timirgaz"
                            2 => "E&#46;E&#46; Kalinina"
                            3 => "A&#46;V&#46; Kozlov"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Zh&#46; Vopr&#46; Neirokhir&#46; Im&#46; NN&#46; Burdenko&#46;"
                        "fecha" => "1996"
                        "numero" => "4"
                        "paginaInicial" => "10"
                        "paginaFinal" => "15"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Flow cytometry in the study of meningiomas&#46; Preliminary results and attempt at clinical correlation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Kujas"
                            1 => "J&#46;G&#46; Rateau"
                            2 => "J&#46;P&#46; Bruch"
                            3 => "J&#46; Van-Effenterre"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch-Anat-Cytol Pathol&#46;"
                        "fecha" => "1996"
                        "volumen" => "44"
                        "numero" => "2&#8211;3"
                        "paginaInicial" => "77"
                        "paginaFinal" => "82"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8794584"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemotherapy for meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;P&#46; Kyritsis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neurooncol&#46;"
                        "fecha" => "1996"
                        "volumen" => "29"
                        "numero" => "3"
                        "paginaInicial" => "269"
                        "paginaFinal" => "272"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8858533"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evidence for clonal spread in the development of multiple meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;J&#46; Larson"
                            1 => "J&#46;M&#46; Tew Jr&#46;"
                            2 => "M&#46; Simon"
                            3 => "A&#46;G&#46; Menon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1995.83.4.0705"
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1995"
                        "volumen" => "83"
                        "numero" => "4"
                        "paginaInicial" => "705"
                        "paginaFinal" => "709"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7674021"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Contemporary management of meningiomas&#46; Radation therapy as an adjuvant and radiosurgery as an altemative to surgical removal&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46;D&#46; Lunsford"
                          ]
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1994.80.2.0187"
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1994"
                        "volumen" => "80"
                        "numero" => "2"
                        "paginaInicial" => "187"
                        "paginaFinal" => "190"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8283254"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy for meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;R&#46; Maor"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J&#46; Neurooncol&#46;"
                        "fecha" => "1996"
                        "volumen" => "29"
                        "numero" => "3"
                        "paginaInicial" => "261"
                        "paginaFinal" => "267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8858532"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frequent loss of chromosome 14 in atypical and malignant meningioma&#58; identification of a putative &#8220;tumor progression&#8221; locus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
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                            0 => "A&#46;G&#46; Menon"
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                            2 => "J&#46;P&#46; von Sattel"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.onc.1200853"
                      "Revista" => array:7 [
                        "tituloSerie" => "Oncogene&#46;"
                        "fecha" => "1997"
                        "volumen" => "14"
                        "numero" => "5"
                        "paginaInicial" => "611"
                        "paginaFinal" => "666"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9053860"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Meningioma&#58; analysis of recurrence and progression following neurosurgical resection"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R&#46;O&#46; Mirimanoff"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
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                        "tituloSerie" => "J&#46; Neurosurg&#46;"
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                        "volumen" => "62"
                        "paginaInicial" => "18"
                        "paginaFinal" => "24"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3964853"
                            "web" => "Medline"
                          ]
                        ]
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                    ]
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                ]
              ]
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            25 => array:3 [
              "identificador" => "bib26"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The usefulness ofradiotherapy in the management of intracraneal meningioma&#58; a review of 29 patients"
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                        0 => array:2 [
                          "etal" => false
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                            3 => "S&#46; Kimura"
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                            5 => "T&#46; Fukuhara"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Nippon Igaku Hoshasen Gakkai Zasshi&#46;"
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                        "volumen" => "57"
                        "numero" => "3"
                        "paginaInicial" => "114"
                        "paginaFinal" => "118"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9077093"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
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                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple meningiomas&#46; Case repart and review of the literature"
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                            0 => "P&#46; O&#39;Neill"
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                  "host" => array:1 [
                    0 => array:1 [
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                        "tituloSerie" => "Surg&#46; Neurol&#46;"
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                        "volumen" => "21"
                        "paginaInicial" => "80"
                        "paginaFinal" => "82"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6689815"
                            "web" => "Medline"
                          ]
                        ]
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                  ]
                ]
              ]
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            27 => array:3 [
              "identificador" => "bib28"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple meningiomas in a patient with constitutional ring chromosoma 22"
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                            0 => "R&#46; Petrella"
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                            4 => "A&#46;C&#46; Kasamassima"
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                        "tituloSerie" => "American Journal of Medical Genetics&#46;"
                        "fecha" => "1993"
                        "volumen" => "47"
                        "paginaInicial" => "184"
                        "paginaFinal" => "186"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8213904"
                            "web" => "Medline"
                          ]
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                ]
              ]
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              "identificador" => "bib29"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Familial meningioma is not allelie to neurofibromatosis 2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;M&#46; Pulst"
                            1 => "G&#46;A&#46; Rouleau"
                            2 => "C&#46; Marineau"
                            3 => "P&#46; Fain"
                            4 => "J&#46;P&#46; Sieb"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurology&#46;"
                        "fecha" => "1993"
                        "volumen" => "43"
                        "paginaInicial" => "2096"
                        "paginaFinal" => "2098"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8413972"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Significaci&#243;n pron&#243;stica de la determinaci&#243;n del anticuerpo monoclonal Ki 67 en los tumores cerebrales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;G&#46; Salazar"
                            1 => "e&#46; Lacruz"
                            2 => "R&#46; Carrillo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Neurocirug&#237;a"
                        "fecha" => "1991"
                        "volumen" => "2"
                        "paginaInicial" => "107"
                        "paginaFinal" => "110"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characterization of nuclear DNA content&#44; proliferation index&#44; and nuclear size in a series of 181 meningiomas&#44; including benign primary&#44; recurrent&#44; and malignant tumars"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "l&#46; Salmon"
                            1 => "R&#46; Kiss"
                            2 => "M&#46; Leviver"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "The American Journal of Surgical Pathology&#46;"
                        "fecha" => "1993"
                        "volumen" => "17"
                        "numero" => "3"
                        "paginaInicial" => "239"
                        "paginaFinal" => "247"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8434704"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Un nouveau gene suppresseur de tumeur responsable de la neurofibromatose de type 2&#44; est altere dans les neurinomes et les meningiomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Sanson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Rev-Neurol-Paris&#46;"
                        "fecha" => "1996"
                        "volumen" => "152"
                        "numero" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "10"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8729390"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib33"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clonaty of multiple meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;P&#46; Stangl"
                            1 => "R&#46; Wellenreuther"
                            2 => "D&#46; Lenartz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/2013.5.JNS122155"
                      "Revista" => array:5 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1997"
                        "paginaInicial" => "853"
                        "paginaFinal" => "858"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23790114"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous plexiform schwannoma associated with neurofibromatosis type 2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;F&#46; Val-Bemal"
                            1 => "J&#46; Figols"
                            2 => "A&#46; V&#225;zquez-Barquero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "C&#225;ncer"
                        "fecha" => "1995"
                        "volumen" => "76"
                        "numero" => "7"
                        "paginaInicial" => "1181"
                        "paginaFinal" => "1186"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8630895"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib35"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Myxomatous meningioma&#58; A meningioma with atypical CT-Scan histological features"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Vaquero"
                            1 => "R&#46; Mart&#237;nez"
                            2 => "S&#46; Coca"
                            3 => "A&#46; Arias"
                            4 => "J&#46; Duarte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Neurocirug&#237;a&#46;"
                        "fecha" => "1992"
                        "numero" => "3"
                        "paginaInicial" => "247"
                        "paginaFinal" => "249"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib36"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiocirug&#237;a estereot&#225;xica&#46; Criterios de selecci&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "F&#46; Vila"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Neurocirug&#237;a&#46;"
                        "fecha" => "1994"
                        "numero" => "5"
                        "paginaInicial" => "340"
                        "paginaFinal" => "347"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evidence for subarachnoid spread in the development of multiple meningiomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Von-Deimling"
                            1 => "J&#46;A&#46; Kraus"
                            2 => "A&#46;P&#46; Stangl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Brain Pathology"
                        "fecha" => "1995"
                        "volumen" => "5"
                        "numero" => "1"
                        "paginaInicial" => "11"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7767486"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
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Vol. 11. Núm. 2.
Páginas 115-124 (enero 1999)
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Vol. 11. Núm. 2.
Páginas 115-124 (enero 1999)
Meningiomas múltiples intracraneales: Desarrollo, manejo y expectativas de tratamiento alternativo. A propósito de tres casos
Intracranial multiple meningiomas. Development, management and alternative treatment. Presentation of three cases
Visitas
6023
J. Dios Seoane, M. García Fantini, S. Amaro, L. López, A. Rodiño, A. Vázquez
Servicios de Neurocirugía. Complejo Hospitalario Juan Canalejo. Servicio Gallego de Salud. La Coruña
J. Díaz*, C. Prada**, V. Goyanes Villaescusa***
* Servicios de Neuroradiología. Complejo Hospitalario Juan Canalejo. Servicio Gallego de Salud. La Coruña
** Servicios de Anatomía Patológica. Complejo Hospitalario Juan Canalejo. Servicio Gallego de Salud. La Coruña
*** Servicios de Genétíca. Complejo Hospitalario Juan Canalejo. Servicio Gallego de Salud. La Coruña
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Resumen

Los meningiomas múltiples intracraneales son procesos raros, generalmente benignos y con entidad propia. Suelen provocar escasos síntomas clínicos, resultando el diagnóstico muchas veces casual y el tratamiento tardío.

Presentamos tres casos de meningiomas múltiples con diferente localización intracraneal, incluida la forma intraventricular. En uno de los pacientes los meningiomas estaban asociados a un schwannoma gigante del acústico. Revisamos la literatura para establecer un protocolo que contribuya a favorecer el diagnóstico, pronóstico tratamiento precoz de estos procesos.

Palabras clave:
Meningiomas múltiples
Diseminación clonal
Citogenética
Manejo
Tratamiento alternativo
Summary

Intracranial multiple meningiomas are infrequent, beningn tumors that are usuaIly asymptomatic so the diagnosis is casual and the treatment is delayed.

We present three patients with multiple meningiomas in different intracraneal locations including the intraventricular formo In one of the patients meningiomas were associated to a giant acoustic schwannoma.

We review the literature in order to built a protocol for improing diagnosis, prognosis and earIy treatment of this pathology.

Key words:
Multiple meningiomas
Clonal spread
Cytogenetic
Management
Alternative treatment

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