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Vol. 11. Núm. 4.
Páginas 297-301 (enero 1999)
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Vol. 11. Núm. 4.
Páginas 297-301 (enero 1999)
Plasmocitoma solitario extramedular (extraóseo) intracraneal: descripción de un nuevo caso y revisión de la literatura
Solitary extramedullary (extraosseous) intracranial plasmacytoma. Report of a new case and review of the literature
Visitas
3196
O. Molina
Departamentos de Neurología, Hospital Universitario, Maracaibo, Venezuela
P. Liscano*, S. Dorfman**, D. Cardozo***, J. Cardozo***
* Departamentos de Neurocirugía, Hospital Universitario, Maracaibo, Venezuela
** Servicio de Oncología, Hospital General del Sur, Maracaibo, Venezuela
*** Cátedra de Neuroanatomía, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela
Este artículo ha recibido
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Resumen

De acuerdo con algunos autores los plasmocitomas solitarios sólo constituyen un estadio en la evolución del mieloma múltiple. Sin embargo, otros afirman que estas lesiones representan entidades bien definidas las cuales responden favorablemente a la cirugía seguida de radioterapia y que acarrean un mejor pronóstico que las discrasias diseminadas de células plasmáticas. Presentamos el caso clínico de un varón de 44 años con historia de cefalea y convulsiones de dos meses de evolución en el que los estudios de neuroimágenes revelaron un tumor parietal derecho adherido a la duramadre, con apariencia de meningioma. La lesión fue extirpada quirúrgicamente y diagnosticada como plasmocitoma solitario después de descartar una neoplasia sistémica de células plasmáticas sobre la base de los resultados obtenidos en pruebas tales como determinación de proteína de Bence-Jones, aspiración y biopsia de médula ósea, examen radiológico simple y gammagrafía ósea. El paciente ha permanecido libre de tumor durante cuatro años y medio contados a partir de la extirpación quirúrgica. Se revisa la literatura relacionada con lesiones similares.

Palabras clave:
Intracraneal
Meningioma
Mieloma
Plasmocitoma
Solitario
Summary

According to different authors, solitary plasmacytomas merely constitute a stage in the development of multiple myeloma, whereas other investigators state that these lesions are well-defined entities that respond favorably to surgery followed by radiation therapy and carry a much better prognosis than disseminated myelomas. We present the case of a 44 year-old man with a chief complaint of headaches and tonic-clonic seizures present for two months prior to admission. Neuroimaging studies revealed a right parietal tumor attached to the duramater suggesting meningioma. The lesion was surgically removed and it was diagnosed as solitary plasmacytoma following laboratory tests that ruled out systemic plasma cell dyscrasia. The patient has remained tumor-free for 4,5 years after surgery.

The medical literatu re concerning similar lesions is reviewed.

Key words:
Intracranial
Meningioma
Myeloma
Plasmacytoma
Solitary

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