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                        "fecha" => "1975"
                        "volumen" => "44"
                        "paginaInicial" => "727"
                        "paginaFinal" => "731"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Ignelzi RJ&#44; VanderArk GD&#58; Analysis of the treatment of bacilar skull fracture with and without antibiotics&#46; J&#46; Neurosurg 43&#58; 721&#8211;726&#46;"
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors for neurosurgical cite infections after craniotomy&#58; A prospective multicentre study of 2944 patients"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "The French Study Group of Neurosurgical Infections&#44; the SEHP and the C-CLIN Paris-Nord"
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; Korinek"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1997"
                        "volumen" => "41"
                        "paginaInicial" => "1073"
                        "paginaFinal" => "1081"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9361061"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Control of hospital infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "E&#46;J&#46;L&#46; Lowbury"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:3 [
                        "titulo" => "A practical handbook"
                        "paginaInicial" => "3031"
                        "serieFecha" => "1981"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of neurosurgical infections by intraoperative antibiotics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46;I&#46; Malis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1979"
                        "volumen" => "5"
                        "paginaInicial" => "334"
                        "paginaFinal" => "343"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/503293"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ventriculostomy related infections"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "C&#46;G&#46; Mayhall"
                            1 => "N&#46;H&#46; Archer"
                            2 => "V&#46; Archer-Lamb"
                            3 => "A&#46;C&#46; Spadora"
                            4 => "J&#46;W&#46; Baggett"
                            5 => "J&#46;D&#46; Ward"
                            6 => "R&#46;K&#46; Narayan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198403013100903"
                      "Revista" => array:6 [
                        "tituloSerie" => "N&#46; Engl J Med"
                        "fecha" => "1984"
                        "volumen" => "310"
                        "paginaInicial" => "553"
                        "paginaFinal" => "559"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6694707"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Operative sepsis in Neurosurgery&#58; A method of classifying surgical cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;K&#46; Narotam"
                            1 => "J&#46;R&#46; van Dellen"
                            2 => "M&#46; du Trevou"
                            3 => "E&#46; Gouws"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1994"
                        "volumen" => "34"
                        "paginaInicial" => "409"
                        "paginaFinal" => "416"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7910668"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infected ventriculostomy&#58; bacteriology and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;K&#46; Ohrstrom"
                            1 => "J&#46;K&#46; Skou"
                            2 => "T&#46; Ejlertsen"
                            3 => "M&#46; Kosteljanetz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Neurochir &#40;Wien&#41;"
                        "fecha" => "1989"
                        "volumen" => "100"
                        "paginaInicial" => "67"
                        "paginaFinal" => "69"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relative risks of ventriculostomy infection and morbidity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;G&#46; Paramore"
                            1 => "D&#46;A&#46; Turner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Neurochir &#40;Wien&#41;"
                        "fecha" => "1994"
                        "volumen" => "127"
                        "paginaInicial" => "79"
                        "paginaFinal" => "84"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of primary wound infection in neurosurgical patients&#58; a 10 year study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;H&#46; Savitz"
                            1 => "S&#46;S&#46; Katz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1986"
                        "volumen" => "18"
                        "paginaInicial" => "685"
                        "paginaFinal" => "688"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3736793"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0001731011000172"
                          "estado" => "S300"
                          "issn" => "00017310"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylactic antibiotics in neurosurgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;H&#46; Savitz"
                            1 => "L&#46;I&#46; Malis"
                            2 => "B&#46;R&#46; Meyers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Surg Neurol"
                        "fecha" => "1974"
                        "volumen" => "2"
                        "paginaInicial" => "95"
                        "paginaFinal" => "100"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4818644"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Randomized clinical trial of intraoperative antimicrobial prophylaxis of infection after neurosurgical procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Shapiro"
                            1 => "U&#46; Wald"
                            2 => "E&#46; Simchen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Hosp Infect"
                        "fecha" => "1986"
                        "volumen" => "8"
                        "paginaInicial" => "283"
                        "paginaFinal" => "295"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2878034"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Some observations on the prophylactic use of procaine-penicilin in operations for protuded intervertebral disk with spinal fusion"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46;P&#46; Sperl"
                            1 => "D&#46;R&#46; Nichols"
                            2 => "W&#46;J&#46; Martin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1956.13.5.0444"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1956"
                        "volumen" => "13"
                        "paginaInicial" => "444"
                        "paginaFinal" => "448"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13367879"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wide variation in risk of wound infection following clean neurosurgery&#46; Implications for perioperative antibiotic prophylaxis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;H&#46; Tenney"
                            1 => "D&#46; Vlahov"
                            2 => "M&#46; Salcman"
                            3 => "T&#46;B&#46; Ducker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1985.62.2.0243"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1985"
                        "volumen" => "62"
                        "paginaInicial" => "243"
                        "paginaFinal" => "247"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3968563"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neurosurgical wound infections&#46; Methodological and clinical factors afecting calculation of infection rates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46; Vlahov"
                            1 => "E&#46; Mongomery"
                            2 => "J&#46;H&#46; Tenney"
                            3 => "S&#46; Kahn-Eisenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J&#46; Neurosurg&#46; Nursing"
                        "fecha" => "1984"
                        "volumen" => "16"
                        "paginaInicial" => "128"
                        "paginaFinal" => "133"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A randomized control trial of perioperative rifampin&#47;tirmetroprim in cerebrospinal Huid shunt surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;C&#46; Walters"
                            1 => "L&#46; Goumnerova"
                            2 => "H&#46;J&#46; Hoffman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Childs Nerv Syst"
                        "fecha" => "1992"
                        "volumen" => "8"
                        "paginaInicial" => "253"
                        "paginaFinal" => "257"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1296606"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Winfield JA&#44; Rosenthal P&#44; Kanter RK&#44; Casella G&#58; Duration of intracranial pressure monitoring does not predict daily risk of infectious complications&#46; Neurosurgery 33&#58; 424&#8211;431&#46;"
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A survey of possible etiologic agents in postoperative craniotomy infections"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;L&#46; Wright"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1966.25.2.0125"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1966"
                        "volumen" => "25"
                        "paginaInicial" => "125"
                        "paginaFinal" => "132"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5911360"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perioperative antibiotic prophylaxis for the prevention of postoperative neurosurgical infections&#58; a randomized clinical trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;F&#46; Young"
                            1 => "P&#46;M&#46; Lawner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1987.66.5.0701"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1987"
                        "volumen" => "66"
                        "paginaInicial" => "701"
                        "paginaFinal" => "706"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3553455"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
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Vol. 11. Núm. 3.
Páginas 196-202 (enero 1999)
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Vol. 11. Núm. 3.
Páginas 196-202 (enero 1999)
Profilaxis antibiótica en neurocirugía
Antibiotic prophylaxis in neurosurgery
Visitas
4841
P. González, R.D. Lobato, G.R. Boto, A. De la Lama, A. Lagares, J.F. Alén
Servicio de Neurocirugía. Hospital 12 de Octubre. Madrid
Este artículo ha recibido
Información del artículo
Resumen

Se realiza una revisión de la literatura sobre el uso de la profilaxis antibiótica en el paciente neuroquirúrgico. Se consideran la clasificación de las infecciones, los aspectos microbiológicos, los factores de riesgo y las pautas a aplicar en la práictica clínica. Se ha realizado además un metaanálisis de los ensayos controlados y no controlados aparecidos hasta la actualidad.

Palabras clave:
Infección, profilaxis
antibiótico
neurocirugía
Summary

The authors reviewed the literature related with the use of prophylactic antibiotics in neurosurgery. Classification of the type of infection, microbiology, risk factors and therapeutic approaches to be used in the clinical setting are considered and a metaanalysis of the previous controlled and uncontrolled clinical trials is made.

Key words:
Infection
prophylaxis
antibiotic
neurosurgery

Artículo

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