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Vol. 2. Issue 4.
Pages 323-328 (January 1991)
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Vol. 2. Issue 4.
Pages 323-328 (January 1991)
Astrocitomas de ventrículo lateral
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A. Isla, F. Alvarez, C. Morales, J. Muñoz, R. Frutos, M.G. Blázquez
Servicios de Neurocirugía, Neurorradiología y Patología. Hospital “La Paz”. Madrid
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Resumen

Presentamos 11 pacientes con astrocitomas de ventrículo lateral de bajo grado de malignidad. La manifestación clínica fue principalmente por síntomas de hipertensión endocraneal, seguido de crisis comiciales. Cinco de los 6 pacientes con crisis comiciales presentaban Esclerosis Tuberosa (ET). La localización de estos tumores en el ventrículo lateral fue de predominio en su porción anterior con 7 casos de los cuales 6 se originaron a nivel del foramen de Monro y 5 de estos 6 tumores en el estudio histológico fueron astrocitomas de tipo gigantocelular subependimario. Las características de la tomografía axial computarizada (TAC) fueron en general hipo o hiperdensos con captación de contraste a nivel de foramen de Monro y de densidad heterogénea en el resto de los tumores. La RM puso de manifiesto con más precisión la extensión y localización del tumor junto con tuberomas en los casos de ET que pasaban desapercibidos con la TAC. Fueron intervenidos todos los casos y reintervenidos dos pacientes. Dos casos fallecieron por sangrado masivo al intentar una extirpación total. Se comentaran las características histológicas así como la evolución de estos procesos.

Palabras clave:
Astrocitomas
Astrocitoma gigantocelular subependimario
Esclerosis tuberosa
Ventrículo lateral
Summary

We present 11 patients with low malignancy astrocytomas in the lateral ventricle. Endocranial hypertension followed by epilepsy were the main clinical manifestation. Five of the six epileptic patients had Tuberous Sclerosis (TS). Six of the seven tumors were located in the anterior portion of the lateral ventricle and originated at the level of Monro's foramen. Histologic study showed that five of the six were subependymal giant-cell astrocytomas. The CT sean showed hypo or hyperdense images with contrast enhanced in the tumors located in the Monro's foramen, and heterogeneous enhancement of the other astrocytomas in other locations of the lateral ventricle. MRI located these tumors more precisely as well as imaging tuberomas in cases were ST was not visible with CT scan.

All cases were operated and two cases required a second operation. Two patients died from bleeding during the attempt of removing all the tumor. Histologic characteristic and evolution of these processes are discussed.

Key words:
Astrocytoma
Subependymal giant-cell astrocytoma
Tuberous sclerosis
Lateral ventricle

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