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Vol. 14. Issue 1.
Pages 41-45 (January 2003)
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Vol. 14. Issue 1.
Pages 41-45 (January 2003)
Hipertermia intracraneal no invasiva mediante la técnica de Transferencia Eléctrica Capacitiva -TEC- (*). Resultados de la termometría cerebral e intratumoral
Non invasive intracranial hyperthermia with Electric Capacitive Transference -ECT- (*) Intratumoral and cerebral thermometry results
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1978
A. Ley-Valle
Servicio de Neurocirugía. HUGTP. Badalona. Barcelona
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Resumen

La finalidad de este trabajo es presentar los resultados del incremento térmico obtenido a nivel cerebral e intratumoral mediante una técnica no invasiva de hipertermia intracraneal con RF de 0.7 MHz, -Transferencia Eléctrica Capacitiva- (TEC), creada en 1985 por INDIBA (*). En la literatura no existen referencias de termometría en tiempo real con un método no invasivo de hipertermia intracraneal. Los valores térmicos obtenidos en los ocho pacientes estudiados mostraron que durante la aplicación de la TEC, existía un diferencial de temperatura a nivel cerebral en función de la profundidad. Entre el tejido tumoral y el cerebral perilesional, la diferencia fue de 0.3 a 0.7 °C. A nivel cerebral, los incrementos de temperatura oscilaron entre 0.7 y 1.5 °C en función del ángulo de incidencia del electrodo externo y de la profundidad de la sonda termométrica. La observación de que en ningún caso se obtuvo en el tejido cerebral adyacente al tumor una temperatura superior a los 39.2 °C, sugiere la inocuidad del método en cuanto a posible afectación del tejido cerebral sano y parece confirmar los datos de ausencia de lesiones sobre los tejidos y órganos de los animales de experimentación, evidenciados en los estudios anatomopatológicos, con la TEC, realizados en 1990. Al mayor incremento térmico y algo más prolongado, observado a nivel tumoral, lo hemos denominado: “efecto invernadero”.

Palabras clave:
Hipertermia intracraneal no invasiva
Termometría cerebral e intratumoral
Transferencia Eléctrica Capacitiva -TEC-
Indiba
Summary

The aim of this work is to present the results of thermic increase obtained at the brain and intratumoral levels through a non invasive technique Electric Capacitive Transference- (ECT), developed in 1985 by Indiba (*). A review of the literature does not provide any reference of cerebral and intratumoral thermometry in real time with a non invasive technique of intracranial hyperthermia. In the 8 studied patients, the increases of temperature in the brain, ranged between 0.7 and 1.5 °C in relation to the depth of the thermometric probe and the incidence angle of the external electrode. Between tumoral and perilesional brain tissues, thermic increase was 0.3 to 0.7 °C greater at tumoral level. The observation that in no case the surrounding brain tissue registered a temperature over 39.2 °C supports the harmlessness of the technique regarding the potential damage to healthy brain tissue and seems to confirm previous data obtained in anatomopathological studies in animal experimentation performed in 1990, which showed an absence of lesions in tissues and organs. The greater and somewhat more prolonged thermic increase observed at tumoral level has been called the “greenhouse effect”.

Key words:
Non invasive intracranial hyperthermia
Brain and intratumoral thermometry
Electric Capacitive Transference (ECT)
Indiba

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