Presentamos una observación de un quiste epidermoide de localización frontal parasagital, en un paciente de 69 años de edad con crisis comiciales de 40 años de evolución, ictus cerebrales. El paciente desarrolló sobre la pared del quiste una neoformación maligna identificada morfológica e inmunohistoquímicamente con la HMb45, como un melanoma maligno.
La falta de antecedentes, el estudio radiológico sistémico, conducen a considerar el diagnóstico de melanoma maligno primario sobre un quiste epidermoide, siendo discutida la histogenie de esta posible asociación.
We present a case of epidermoid cyst located in fronto-temporal area in a 69 years old patient with comitial crisis of 40 years evolution and cerebral ictus. The patient developed, over the cyst wall, a malignant tumor identified morphollogically and immunohistochemically, with aid of HMB-45 monoclonal antibody, as a malignant melanoma.
The lack of records the propper characteristics and the sistemic radiologic study of this lesion, lead to consider a diagnostic of primary malignant melanoma over a epidermoid cyst, discussing the histogenesis of this possible association.
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