Nocardia infection is not rare as generally been assumed and its mortality rate is high. It is isolated from plants and soil in most regions of the worid. The hosts usually have predisposing conditions and the infection is acquired through the respiratory tract or skin. Nocardial organisms have a tendency to dissemi-nate hematogenously from the primary site of infection to brain, kidney, joints, bones and eyes. Sulfonamides are preferred empirically for the treatment. Because of high relapse rates, the treatment must be continued for 12 months. In nocardia farcinica infection, the characte-ristic resistance pattem to cephalosporines must be kept in mind. In this article, a rare case of nocardia farcinica infection with a solitary cerebral abscess is presented and the literature is reviewed.
La infección por nocardia no es rara, como se cree y su tasa de mortalidad es alta. Se aisla en las plantas y en el suelo en muchas regiones del mundo. Los huéspedes reúnen factores predisponentes y se adquiere a través del tracto respiratorio o de la piel. Estos microorganismos tienen tendencia a diseminarse por vía hematógena desde el punto de la infección hasta el cerebro, riñon, articulaciones, huesos y ojos. Se prefieren las sulfami-das, empíricamente, para el tratamiento. A causa del gran número de recurrencias, el tratamiento debe continuar durante 12 meses. En la infección por nocardia farcinica, debe tenerse en cuenta la resistencia característica a las cefalosporinas. En este artículo, se presenta un caso raro de infección por nocardia farcinica, con un absceso cerebral solitario. Se revisa la literatura.
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