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      "titulo" => "Hidrocefalia en los tumores de fosa posterior en la infancia. ¿Necesidad de derivación permanente de líquido cefalorraquídeo?"
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          "autoresLista" => "J.M. Poch Puig, J. Bosch Blancafort, P. Nogués Bara, E. Rubio García"
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              "nombre" => "J.M."
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              "apellidos" => "Rubio García"
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          "autoresLista" => "J. Sánchez de Toledo"
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              "apellidos" => "Sánchez de Toledo"
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    "cita" => "Neurocirugia. 1992;3:217-21"
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      "titulo" => "Hematomas intracerebrales crónicos capsulados. Presentación de tres casos y revisión de la literatura"
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        0 => array:2 [
          "autoresLista" => "J. Viñuela, A. Mostaza, J.M. Abad, J. Cosamalon, J. Fernández, M. Mazabel"
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            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Viñuela"
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              "apellidos" => "Mostaza"
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    "titulo" => "Diagnóstico «in vivo», mediante Resonancia Magnética, de tumores cerebrales experimentales"
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            "nombre" => "J."
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            "apellidos" => "Arias"
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            "nombre" => "F.J."
            "apellidos" => "González"
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            "nombre" => "M."
            "apellidos" => "Zurita"
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            "apellidos" => "Oya"
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            "nombre" => "C."
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          0 => array:1 [
            "entidad" => "Laboratorio de Neuro-oncología experimental, Servicio de Neurocirugía, Clínica Puerta de Hierro, Universidad Autónoma&#59; Centro de Resonancia Magnética Madrid y Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense"
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        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se presenta la experiencia preliminar en el diagn&#243;stico &#171;in vivo&#187;&#44; mediante Resonancia Magn&#233;tica &#40;MR&#41;&#44; de los tumores cerebrales inducidos en la rata por medio de la administraci&#243;n prenatal de etil-nitrosourea&#46; Los resultados obtenidos muestran que la RM es altamente &#250;til para el diagn&#243;stico y localizaci&#243;n de dichos tumores&#44; facilitando la evaluaci&#243;n de ensayos terap&#233;uticos en neuro-oncolog&#237;a experimental&#46;</p>"
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        "titulo" => "Summary"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The study with Magnetic Resonance Imaging of experimental brain tumors&#44; induced after prenatal administration of ethyl-nitrosourea in rats&#44; is presented&#46; The results that we have obtained show that MRI is very useful in the diagnosis and localization of the ENU-induced tumors&#46; This finding facilitates the appraisement of therapeutic trials in experimental neurooncology&#46;</p>"
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        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Vaquero&#44; J&#46;&#59; Arias&#44; A&#46;&#59;Gonz&#225;lez&#44; F&#46;J&#46;&#59; Zurita&#44; M&#46;&#59; Oya&#44; S&#46;&#59; Morales&#44; C&#46;&#58; Diagn&#243;stico &#171;in vivo&#187;&#44; mediante Resonancia Magn&#233;tica&#44; de tumores cerebrales experimentales&#46; Neurocirug&#237;a 1992&#59; 3&#58; 223&#8211;227&#46;</p>"
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                          "autores" => array:3 [
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                            2 => "S&#46; Pezzotta"
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                      "titulo" => "Experimental brain tumours induced in rats by nitrosourea derivatives&#46; Part 2&#46; Morphological aspects of nitrosoethylurea tumours obtained by transplacental induction"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4321468"
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                        "tituloSerie" => "Food Cosmet&#46; Toxicol&#46;"
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                      "titulo" => "Transplacental induction of malignant tumors of the nervous system&#46; I&#46; ENU in BD IX rats"
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                      "Revista" => array:5 [
                        "tituloSerie" => "Z&#46; Krebsforch"
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                        "fecha" => "1973"
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enero 1992 Diagnóstico «in vivo», mediante Resonancia Magnética, de tumores cerebrales...
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Vol. 3. Núm. 3.
Páginas 223-227 (enero 1992)
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Vol. 3. Núm. 3.
Páginas 223-227 (enero 1992)
DOI: 10.1016/S1130-1473(92)70884-7
Diagnóstico «in vivo», mediante Resonancia Magnética, de tumores cerebrales experimentales
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J. Vaquero, A. Arias, F.J. González, M. Zurita, S. Oya, C. Morales
Laboratorio de Neuro-oncología experimental, Servicio de Neurocirugía, Clínica Puerta de Hierro, Universidad Autónoma; Centro de Resonancia Magnética Madrid y Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense
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Resumen

Se presenta la experiencia preliminar en el diagnóstico «in vivo», mediante Resonancia Magnética (MR), de los tumores cerebrales inducidos en la rata por medio de la administración prenatal de etil-nitrosourea. Los resultados obtenidos muestran que la RM es altamente útil para el diagnóstico y localización de dichos tumores, facilitando la evaluación de ensayos terapéuticos en neuro-oncología experimental.

Palabras clave:
Resonancia Magnética
ENU
Tumores cerebrales experimentales
Summary

The study with Magnetic Resonance Imaging of experimental brain tumors, induced after prenatal administration of ethyl-nitrosourea in rats, is presented. The results that we have obtained show that MRI is very useful in the diagnosis and localization of the ENU-induced tumors. This finding facilitates the appraisement of therapeutic trials in experimental neurooncology.

Key words:
Magnetic Resonance Imaging
ENU
Experimental brain tumors

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