array:23 [
  "pii" => "S1130147392708847"
  "issn" => "11301473"
  "doi" => "10.1016/S1130-1473(92)70884-7"
  "estado" => "S300"
  "fechaPublicacion" => "1992-01-01"
  "aid" => "70884"
  "copyright" => "Sociedad Española de Neurocirugía"
  "copyrightAnyo" => "1992"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Neurocirugia. 1992;3:223-7"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2048
    "formatos" => array:3 [
      "EPUB" => 15
      "HTML" => 781
      "PDF" => 1252
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1130147392708859"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(92)70885-9"
    "estado" => "S300"
    "fechaPublicacion" => "1992-01-01"
    "aid" => "70885"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Neurocirugia. 1992;3:229-32"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2068
      "formatos" => array:3 [
        "EPUB" => 19
        "HTML" => 881
        "PDF" => 1168
      ]
    ]
    "es" => array:9 [
      "idiomaDefecto" => true
      "titulo" => "Hidrocefalia en los tumores de fosa posterior en la infancia. ¿Necesidad de derivación permanente de líquido cefalorraquídeo?"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "229"
          "paginaFinal" => "232"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "J.M. Poch Puig, J. Bosch Blancafort, P. Nogués Bara, E. Rubio García"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "J.M."
              "apellidos" => "Poch Puig"
            ]
            1 => array:2 [
              "nombre" => "J."
              "apellidos" => "Bosch Blancafort"
            ]
            2 => array:2 [
              "nombre" => "P."
              "apellidos" => "Nogués Bara"
            ]
            3 => array:2 [
              "nombre" => "E."
              "apellidos" => "Rubio García"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "J. Sánchez de Toledo"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Sánchez de Toledo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147392708859?idApp=UINPBA00004B"
    "url" => "/11301473/0000000300000003/v1_201305151419/S1130147392708859/v1_201305151419/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1130147392708835"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(92)70883-5"
    "estado" => "S300"
    "fechaPublicacion" => "1992-01-01"
    "aid" => "70883"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Neurocirugia. 1992;3:217-21"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1594
      "formatos" => array:3 [
        "EPUB" => 17
        "HTML" => 718
        "PDF" => 859
      ]
    ]
    "es" => array:9 [
      "idiomaDefecto" => true
      "titulo" => "Hematomas intracerebrales crónicos capsulados. Presentación de tres casos y revisión de la literatura"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "217"
          "paginaFinal" => "221"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "J. Viñuela, A. Mostaza, J.M. Abad, J. Cosamalon, J. Fernández, M. Mazabel"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Viñuela"
            ]
            1 => array:2 [
              "nombre" => "A."
              "apellidos" => "Mostaza"
            ]
            2 => array:2 [
              "nombre" => "J.M."
              "apellidos" => "Abad"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Cosamalon"
            ]
            4 => array:2 [
              "nombre" => "J."
              "apellidos" => "Fernández"
            ]
            5 => array:2 [
              "nombre" => "M."
              "apellidos" => "Mazabel"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "M.T. Rivas"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "M.T."
              "apellidos" => "Rivas"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147392708835?idApp=UINPBA00004B"
    "url" => "/11301473/0000000300000003/v1_201305151419/S1130147392708835/v1_201305151419/es/main.assets"
  ]
  "es" => array:12 [
    "idiomaDefecto" => true
    "titulo" => "Diagnóstico «in vivo», mediante Resonancia Magnética, de tumores cerebrales experimentales"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "223"
        "paginaFinal" => "227"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "J. Vaquero, A. Arias, F.J. González, M. Zurita, S. Oya, C. Morales"
        "autores" => array:6 [
          0 => array:2 [
            "nombre" => "J."
            "apellidos" => "Vaquero"
          ]
          1 => array:2 [
            "nombre" => "A."
            "apellidos" => "Arias"
          ]
          2 => array:2 [
            "nombre" => "F.J."
            "apellidos" => "González"
          ]
          3 => array:2 [
            "nombre" => "M."
            "apellidos" => "Zurita"
          ]
          4 => array:2 [
            "nombre" => "S."
            "apellidos" => "Oya"
          ]
          5 => array:2 [
            "nombre" => "C."
            "apellidos" => "Morales"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Laboratorio de Neuro-oncología experimental, Servicio de Neurocirugía, Clínica Puerta de Hierro, Universidad Autónoma&#59; Centro de Resonancia Magnética Madrid y Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec162274"
          "palabras" => array:3 [
            0 => "Resonancia Magnética"
            1 => "ENU"
            2 => "Tumores cerebrales experimentales"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec162275"
          "palabras" => array:3 [
            0 => "Magnetic Resonance Imaging"
            1 => "ENU"
            2 => "Experimental brain tumors"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se presenta la experiencia preliminar en el diagn&#243;stico &#171;in vivo&#187;&#44; mediante Resonancia Magn&#233;tica &#40;MR&#41;&#44; de los tumores cerebrales inducidos en la rata por medio de la administraci&#243;n prenatal de etil-nitrosourea&#46; Los resultados obtenidos muestran que la RM es altamente &#250;til para el diagn&#243;stico y localizaci&#243;n de dichos tumores&#44; facilitando la evaluaci&#243;n de ensayos terap&#233;uticos en neuro-oncolog&#237;a experimental&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The study with Magnetic Resonance Imaging of experimental brain tumors&#44; induced after prenatal administration of ethyl-nitrosourea in rats&#44; is presented&#46; The results that we have obtained show that MRI is very useful in the diagnosis and localization of the ENU-induced tumors&#46; This finding facilitates the appraisement of therapeutic trials in experimental neurooncology&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Vaquero&#44; J&#46;&#59; Arias&#44; A&#46;&#59;Gonz&#225;lez&#44; F&#46;J&#46;&#59; Zurita&#44; M&#46;&#59; Oya&#44; S&#46;&#59; Morales&#44; C&#46;&#58; Diagn&#243;stico &#171;in vivo&#187;&#44; mediante Resonancia Magn&#233;tica&#44; de tumores cerebrales experimentales&#46; Neurocirug&#237;a 1992&#59; 3&#58; 223&#8211;227&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Teratogenic and carcinogenic effects in the offspring after a single injection of ethylnitrosourea to pregnant rats"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Druckrey"
                            1 => "S&#46; Ivankovic"
                            2 => "R&#46; Preussmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nature"
                        "fecha" => "1966"
                        "volumen" => "210"
                        "paginaInicial" => "1378"
                        "paginaFinal" => "1379"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6007120"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally or subcutaneously to newborn rats&#46; Morphological and biochemical characteristics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "E&#46; Grossi-Paoletti"
                            1 => "P&#46; Paoletti"
                            2 => "S&#46; Pezzotta"
                            3 => "D&#46; Schiffer"
                            4 => "A&#46; Fabiani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1972.37.5.0580"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1972"
                        "volumen" => "37"
                        "paginaInicial" => "580"
                        "paginaFinal" => "590"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5076376"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experimental brain tumours induced in rats by nitrosourea derivatives&#46; Part 2&#46; Morphological aspects of nitrosoethylurea tumours obtained by transplacental induction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Grossi-Paoletti"
                            1 => "P&#46; Paoletti"
                            2 => "D&#46; Schiffer"
                            3 => "A&#46; Fabiani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurol&#46; Sci&#46;"
                        "fecha" => "1970"
                        "volumen" => "11"
                        "paginaInicial" => "573"
                        "paginaFinal" => "581"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4321468"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experimental transplantation gliomas in the adult cat brain&#46; 2&#46; Pathophysiology and magnetic resonance imaging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;A&#46; Hossman"
                            1 => "J&#46; Szymas"
                            2 => "K&#46; Seo"
                            3 => "J&#46; Assheuer"
                            4 => "S&#46; Krajewski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Neurochir&#46; &#40;Wien&#41;&#46;"
                        "fecha" => "1989"
                        "volumen" => "98"
                        "paginaInicial" => "189"
                        "paginaFinal" => "200"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2741748"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Carcinog&#233;nesis in the progeny after exposure of pregnant animals"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Ivankovic"
                            1 => "H&#46; Druckrey"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Food Cosmet&#46; Toxicol&#46;"
                        "fecha" => "1968"
                        "volumen" => "6"
                        "paginaInicial" => "584"
                        "paginaFinal" => "585"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5732318"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transplacental induction of malignant tumors of the nervous system&#46; I&#46; ENU in BD IX rats"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Ivankovic"
                            1 => "H&#46; Druckrey"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Z&#46; Krebsforch"
                        "fecha" => "1968"
                        "volumen" => "71"
                        "paginaInicial" => "320"
                        "paginaFinal" => "360"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "W&#46; J&#228;nisch"
                            1 => "D&#46; Schreiber"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:2 [
                        "titulo" => "Experimental Tumors of the Central Nervous System"
                        "serieFecha" => "1977"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tumours of the nervous system induced in rats by the neonatal administration of N-ethyl-N-nitrosourea"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46;L&#46; Jones"
                            1 => "C&#46;E&#46; Searle"
                            2 => "W&#46;T&#46; Smith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/path.1711090206"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Pathol"
                        "fecha" => "1973"
                        "volumen" => "109"
                        "paginaInicial" => "123"
                        "paginaFinal" => "139"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4720907"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemical Carcinog&#233;nesis in the Nervous System"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Kleihues"
                            1 => "P&#46;L&#46; Lantos"
                            2 => "P&#46;N&#46; Magee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int&#46; Rev&#46; Exp&#46; Pathol&#46;"
                        "fecha" => "1976"
                        "volumen" => "15"
                        "paginaInicial" => "153"
                        "paginaFinal" => "232"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/176123"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of perchlorate on the localization of 99Tc-pertechnetate in a mouse brain sarcoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46; Konikowski"
                            1 => "T&#46;P&#46; Haynie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J&#46; Nunl&#46; Med&#46;"
                        "fecha" => "1970"
                        "volumen" => "11"
                        "paginaInicial" => "443"
                        "paginaFinal" => "448"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemical induction of tumours in the nervous system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;L&#46; Lantos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Brain Tumours&#46; Scientific basis&#44; clinical investigation and current therapy"
                        "paginaInicial" => "85"
                        "paginaFinal" => "108"
                        "serieFecha" => "1980"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patterns of tumor growth"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Schiffer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:6 [
                        "editores" => "M&#46;Salcman"
                        "paginaInicial" => "185"
                        "paginaFinal" => "210"
                        "serieVolumen" => "4"
                        "serieTitulo" => "Neurobiology of Brain Tumors&#46; Concepts in Neurosurgery"
                        "serieFecha" => "1991"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cerebral tumors induced by transplacental ENU&#58; Study of the different tumoral stages&#44; particularly of early proliferations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46; Schiffer"
                            1 => "M&#46;T&#46; Giordana"
                            2 => "S&#46; Pezzotta"
                            3 => "C&#46; Lechner"
                            4 => "P&#46; Paoletti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Neuropathol&#46; &#40;Berl&#46;&#41;"
                        "fecha" => "1978"
                        "volumen" => "41"
                        "paginaInicial" => "27"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Magnetic resonance imaging of ferrite-labeled neuro-transplants"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Smith"
                            1 => "L&#46; Clarke"
                            2 => "G&#46; Arendash"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Soco Neurosci&#46; Abst&#46;"
                        "fecha" => "1988"
                        "volumen" => "14"
                        "paginaInicial" => "1142"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The pursuit of selectivity and refinement in the radioisotopic diagnosis of intracranial tumors&#46; Part II&#46; Diagnostic and therapeutic aspects of brain tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;H&#46; Tator"
                            1 => "T&#46;P&#46; Morley"
                            2 => "W&#46; Paul"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann&#46; N&#46;Y&#46; Acad&#46; Sci&#46;"
                        "fecha" => "1969"
                        "volumen" => "159"
                        "paginaInicial" => "533"
                        "paginaFinal" => "551"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "In vivo magnetic resonance imaging of fetal cat neural tissue transplants in the adult cat spinal cord"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46;D&#46; Wirth III"
                            1 => "D&#46;P&#46; Theele"
                            2 => "T&#46;H&#46; Mareci"
                            3 => "D&#46;K&#46; Anderson"
                            4 => "S&#46;A&#46; Brown"
                            5 => "P&#46;J&#46; Reier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1992.76.2.0261"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Neurosurg&#46;"
                        "fecha" => "1992"
                        "volumen" => "76"
                        "paginaInicial" => "261"
                        "paginaFinal" => "274"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1730955"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/11301473/0000000300000003/v1_201305151419/S1130147392708847/v1_201305151419/es/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/11301473/0000000300000003/v1_201305151419/S1130147392708847/v1_201305151419/es/main.pdf?idApp=UINPBA00004B&text.app=https://revistaneurocirugia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147392708847?idApp=UINPBA00004B"
]
Compartir
Información de la revista
Vol. 3. Núm. 3.
Páginas 223-227 (enero 1992)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 3. Núm. 3.
Páginas 223-227 (enero 1992)
Diagnóstico «in vivo», mediante Resonancia Magnética, de tumores cerebrales experimentales
Visitas
2034
J. Vaquero, A. Arias, F.J. González, M. Zurita, S. Oya, C. Morales
Laboratorio de Neuro-oncología experimental, Servicio de Neurocirugía, Clínica Puerta de Hierro, Universidad Autónoma; Centro de Resonancia Magnética Madrid y Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense
Este artículo ha recibido
Información del artículo
Resumen
Bibliografía
Descargar PDF
Estadísticas
Resumen

Se presenta la experiencia preliminar en el diagnóstico «in vivo», mediante Resonancia Magnética (MR), de los tumores cerebrales inducidos en la rata por medio de la administración prenatal de etil-nitrosourea. Los resultados obtenidos muestran que la RM es altamente útil para el diagnóstico y localización de dichos tumores, facilitando la evaluación de ensayos terapéuticos en neuro-oncología experimental.

Palabras clave:
Resonancia Magnética
ENU
Tumores cerebrales experimentales
Summary

The study with Magnetic Resonance Imaging of experimental brain tumors, induced after prenatal administration of ethyl-nitrosourea in rats, is presented. The results that we have obtained show that MRI is very useful in the diagnosis and localization of the ENU-induced tumors. This finding facilitates the appraisement of therapeutic trials in experimental neurooncology.

Key words:
Magnetic Resonance Imaging
ENU
Experimental brain tumors

Artículo

Opciones para acceder a los textos completos de la publicación Neurocirugía
Socio
Socio de la Sociedad Española de Neurocirugía

Si es la primera vez que accede a la web puede obtener sus claves de acceso poniéndose en contacto con Elsevier España en suscripciones@elsevier.com o a través de su teléfono de Atención al Cliente 902 88 87 40 si llama desde territorio español o del +34 932 418 800 (de 9 a 18h., GMT + 1) si lo hace desde el extranjero.

Si ya tiene sus datos de acceso, clique aquí.

Si olvidó su clave de acceso puede recuperarla clicando aquí y seleccionando la opción "He olvidado mi contraseña".

Suscriptor
Suscriptor de la revista

Si ya tiene sus datos de acceso, clique aquí.

Si olvidó su clave de acceso puede recuperarla clicando aquí y seleccionando la opción "He olvidado mi contraseña".
Suscribirse
Suscribirse a:

Neurocirugía

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 19,34 €

Comprar ahora
Contactar
Teléfono para suscripciones e incidencias
De lunes a viernes de 9h a 18h (GMT+1) excepto los meses de julio y agosto que será de 9 a 15h
Llamadas desde España
932 415 960
Llamadas desde fuera de España
+34 932 415 960
Email
Idiomas
Neurocirugía
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?