Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptina y efedrina. Revisión fisiopatológica
Akinetic mutism related to hydrocephalus and cerebellar surgery treated with bromocriptine and ephedrine. A pathophysiological review
O. Mateo-Sierra
, F.A. Gutiérrez, C. Fernández-Carballal, D. Pinilla, B. Mosqueira, B. Iza, R. Carrillo
Servicio de Neurocirugía. Hospital General Universitario Gregorio Marañón. Madrid
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"apellidos" => "Brell" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S113014730570419X?idApp=UINPBA00004B" "url" => "/11301473/0000001600000002/v1_201305151236/S113014730570419X/v1_201305151236/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147305704176" "issn" => "11301473" "doi" => "10.1016/S1130-1473(05)70417-6" "estado" => "S300" "fechaPublicacion" => "2005-01-01" "aid" => "70417" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2005;16:124-33" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3213 "formatos" => array:3 [ "EPUB" => 18 "HTML" => 2191 "PDF" => 1004 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Síndromes de hiperdrenaje de las válvulas en hidrocefalia infantil" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "124" "paginaFinal" => "133" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Syndromes of overdrainage of ventricular shunting in childhood hydrocephalus" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.F. 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Revisión fisiopatológica" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "134" "paginaFinal" => "141" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "O. Mateo-Sierra, F.A. Gutiérrez, C. Fernández-Carballal, D. Pinilla, B. Mosqueira, B. Iza, R. Carrillo" "autores" => array:7 [ 0 => array:3 [ "nombre" => "O." "apellidos" => "Mateo-Sierra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "F.A." "apellidos" => "Gutiérrez" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Fernández-Carballal" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Pinilla" ] 4 => array:2 [ "nombre" => "B." "apellidos" => "Mosqueira" ] 5 => array:2 [ "nombre" => "B." "apellidos" => "Iza" ] 6 => array:2 [ "nombre" => "R." "apellidos" => "Carrillo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital General Universitario Gregorio Marañón. Madrid" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia postal: Servicio de Neurocirugía. Hospital General Universitario “Gregorio Mara-ñón”. C/Dr. Esquerdo 46. 28007-Madrid." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Akinetic mutism related to hydrocephalus and cerebellar surgery treated with bromocriptine and ephedrine. A pathophysiological review" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-06-03" "fechaAceptado" => "2004-08-18" "PalabrasClave" => array:2 [ "es" => array:2 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec158817" "palabras" => array:5 [ 0 => "Mutismo acinético" 1 => "Bromocriptina" 2 => "Agonista dopaminérgico" 3 => "Fosa posterior" 4 => "Hidrocefalia" ] ] 1 => array:4 [ "clase" => "abr" "titulo" => "Abreviaturas" "identificador" => "xpalclavsec158815" "palabras" => array:5 [ 0 => "AM" 1 => "MA" 2 => "BC" 3 => "DUP" 4 => "GCS" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec158816" "palabras" => array:5 [ 0 => "Akinetic mutism" 1 => "Bromocriptine" 2 => "Dopa-mine agonist" 3 => "Posterior fossa" 4 => "Hydrocephalus" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El mutismo acinético (MA) es un trastorno del comportamiento, caracterizado por la incapacidad para moverse o hablar en pacientes despiertos. Típicamente ha sido descrito como una complicación transitoria de la cirugía de tumores de fosa posterior. Sin embargo, el MA también puede aparecer tras múltiples fallos valvulares en pacientes hidrocefálicos. En estos casos, el MA no mejora espontáneamente, ni con revisiones valvulares, pero puede responder al tratamiento con bromocriptina. Presentamos una paciente con MA tras una cirugía de fosa posterior, complicada por una ventriculitis con dilataciones ventriculares repetidas, que sólo mejoró con bromocriptina. Revisamos la flsiopatología del MA. Aunque ésta no sea bien conocida, parece que la afectación del núcleo dentado y de sus eferencias (principalmente de glutamato) sería responsable del MA de origen cerebeloso, mientras que la afectación de las vías monoaminérgicas paraventri-culares explicaría el MA relacionado con dilataciones ventriculares repetidas y que responde al tratamiento con bromocriptina. Aun así, se requiere un estudio más profundo de esta patología para aclarar su etiología.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Akinetic mutism (AM) is a behavioral disorder characterized by impossibility to move or speak in awake patients. lt has been typically described as a transient disorder following posterior fossa tumour resection. Besides, AM may also appear after recurrent shunt failures in hydrocephalic patients, with no tendency towards improvement, either spontaneously or with shunt revisions. However successful treatment of this second type of AM has been achieved with bromocriptine. We present a patient who developed AM after a posterior fossa surgery complicated by ventriculitis and múltiple hydrocephalic events. AM only improved with bromocriptine. We review AM pathophysiology. Although not well known, it appears to be quite different, depending on its cerebellar or hydrocephalic origin. Damage to dentate nucleus or its efferents (mainly of glutamate) should promote AM of cerebellar origin, while damage to paraventricular monoaminergic pathways could explain AM related to repeated shunt failures which has successful response to bromocriptine treatment. However, a more complete study of this disorder is required to ascertain its aetiology.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Mateo-Sierra, O.; Gutiérrez, F.A.; Fernández-Carba-llal, C; Pinilla, D.; Mosqueira, B.; Iza, B.; Carrillo, F.: Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptma y efedrina. Revisión fisiopatológica. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2023 Marzo | 15 | 2 | 17 |
| 2020 Diciembre | 1 | 0 | 1 |
| 2020 Agosto | 1 | 0 | 1 |
| 2020 Marzo | 4 | 0 | 4 |
| 2019 Octubre | 0 | 2 | 2 |
| 2019 Agosto | 5 | 0 | 5 |
| 2019 Abril | 2 | 0 | 2 |
| 2018 Septiembre | 3 | 0 | 3 |
| 2018 Marzo | 0 | 2 | 2 |
| 2018 Febrero | 15 | 31 | 46 |
| 2018 Enero | 25 | 56 | 81 |
| 2017 Diciembre | 21 | 47 | 68 |
| 2017 Noviembre | 37 | 102 | 139 |
| 2017 Octubre | 16 | 55 | 71 |
| 2017 Septiembre | 16 | 53 | 69 |
| 2017 Agosto | 14 | 70 | 84 |
| 2017 Julio | 20 | 30 | 50 |
| 2017 Junio | 22 | 61 | 83 |
| 2017 Mayo | 33 | 60 | 93 |
| 2017 Abril | 20 | 50 | 70 |
| 2017 Marzo | 23 | 79 | 102 |
| 2017 Febrero | 7 | 70 | 77 |
| 2017 Enero | 8 | 25 | 33 |
| 2016 Diciembre | 20 | 34 | 54 |
| 2016 Noviembre | 20 | 52 | 72 |
| 2016 Octubre | 34 | 69 | 103 |
| 2016 Septiembre | 63 | 130 | 193 |
| 2016 Agosto | 95 | 92 | 187 |
| 2016 Julio | 40 | 49 | 89 |
| 2015 Diciembre | 3 | 0 | 3 |
| 2015 Julio | 6 | 6 | 12 |
| 2015 Junio | 32 | 77 | 109 |
| 2015 Mayo | 32 | 63 | 95 |
| 2015 Abril | 31 | 57 | 88 |
| 2015 Marzo | 36 | 49 | 85 |
| 2015 Febrero | 16 | 36 | 52 |
| 2015 Enero | 32 | 52 | 84 |
| 2014 Diciembre | 18 | 33 | 51 |
| 2014 Noviembre | 21 | 47 | 68 |
| 2014 Octubre | 33 | 79 | 112 |
| 2014 Septiembre | 26 | 74 | 100 |
| 2014 Agosto | 20 | 48 | 68 |
| 2014 Julio | 17 | 33 | 50 |
| 2014 Junio | 34 | 58 | 92 |
| 2014 Mayo | 21 | 66 | 87 |
| 2014 Abril | 17 | 52 | 69 |
| 2014 Marzo | 22 | 56 | 78 |
| 2014 Febrero | 15 | 54 | 69 |
| 2014 Enero | 14 | 57 | 71 |
| 2013 Diciembre | 13 | 47 | 60 |
| 2013 Noviembre | 19 | 59 | 78 |
| 2013 Octubre | 16 | 87 | 103 |
| 2013 Septiembre | 25 | 59 | 84 |
| 2013 Agosto | 22 | 75 | 97 |
| 2013 Julio | 28 | 77 | 105 |
| 2013 Junio | 23 | 66 | 89 |
| 2013 Mayo | 15 | 67 | 82 |
| 2013 Abril | 10 | 58 | 68 |
| 2013 Marzo | 13 | 46 | 59 |
| 2013 Febrero | 11 | 30 | 41 |
| 2013 Enero | 18 | 29 | 47 |
| 2012 Diciembre | 9 | 25 | 34 |
| 2012 Noviembre | 1 | 11 | 12 |
| 2012 Octubre | 0 | 1 | 1 |
| 2012 Septiembre | 0 | 3 | 3 |
| 2012 Enero | 13 | 0 | 13 |
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