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      "titulo" => "Epidemiología de los tumores intracraneales en pacientes de edad avanzada"
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se analizaron 10 pacientes con ependimomas anapl&#225;sicos&#44; hospitalizados entre enero de 1970 y diciembre de 1992&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La edad oscil&#243; entre 1 y 46 a&#241;os con un promedio de 13&#44;8 a&#241;os&#46; Siete eran hombres y 3 mujeres&#46; El tiempo de duraci&#243;n de la enfermedad fue de 2 a 24 meses&#46; En el cuadro cl&#237;nico predominaron&#58; hipertensi&#243;n endocraneal&#44; d&#233;ficit de pares craneales y s&#237;ndrome cerebeloso&#46; Siete tumores se localizaron en el IV ventr&#237;culo &#40;5 en el velo inferior y 2 en el velo superior&#41;&#44; 2 en el ventr&#237;culo lateral&#44; y 1 en el III ventr&#237;culo&#46; Todos los pacientes presentaron hidrocefalia necesitando derivaci&#243;n ventricular&#44; 5 de ellos antes de realizar la craneotom&#237;a&#46; Se realiz&#243; resecci&#243;n tumoral completa en 5 casos y parcial en otros 5&#46; Cinco pacientes recibieron radioterapia tras la cirug&#237;a y 4 de ellos radioterapia m&#225;s quimioterapia&#46; En el seguimiento de 1 a 10 a&#241;os&#44; 6 de ellos presentaban secuelas y 2 fallecieron&#44; uno por bronconeumon&#237;a y el otro por el propio tumor&#46; Tres de 5 pacientes presentaron c&#233;lulas neopl&#225;sicas en L&#46;C&#46;R&#46;&#44; y uno de estos adem&#225;s met&#225;stasis en m&#233;dula cervical de la que fue operado&#46; Un caso present&#243; meningoencefalitis por c&#225;ndida albicans&#44; resuelta con antibi&#243;ticos&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se concluye que los ependimomas anapl&#225;sicos intraventriculares se presentan preferentemente en menores de 15 a&#241;os&#44; localiz&#225;ndose fundamentalmente en el IV ventr&#237;culo&#46; Estos tumores conllevan una gran morbilidad neurol&#243;gica&#44; y el tratamiento quir&#250;rgico m&#225;s radioterapia representa la mejor actitud terap&#233;utica&#46;</p>"
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        "titulo" => "Summary"
        "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We have analyzed 10 patients with intraventricular anaplastic ependymomas studied between January 1970 and December 1992&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The age ranged from 1 to 46 years with a mean age of 13&#44;8 years&#46; Seven patients were males and 3 were females&#46; The duration of the disease ranged between 2 and 24 months&#46; Raised intracranial pressure&#44; cranial nerve deficit and cerebellar syndrome were the predominant clinical manifestations&#46; Seven of the tumors were localized in the IV ventricle &#40;5 in the inferior velum and 2 in the superior velum&#41;&#44; 2 in the lateral ventricle and 1 in the III ventricle&#46; All the patients showed hydrocephalus and it was necessary to implant a ventriculo-peritoneal CSF shunt in 5 of them before performing craneotomy&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Complete tumor resection was done in 5 cases and partial in another 5 cases&#46; It was followed by radiotherapy in 5 cases&#44; and by radiotherapy and chemotherapy in 4&#46; At follow-up&#44; ranging from 1 to 10 years&#44; 6 of the patients had neurological deficits and three of the 5 patients had neoplasic cells in the cerebral fluid&#44; and 1 developed spinal metastases&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The conclusions are that intraventricular anaplastic ependymomas predominantly occur in individuals under 15 years of age&#44; are mainly located in the IV ventricle&#44; and produce a severe neurologic morbidity&#46; Surgical treatment followed by radiotherapy improves the final prognosis of these patients&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Posadas Narro&#44; G&#46;&#59; Vaquero Crespo&#44; J&#46;&#59; Pozo Garc&#237;a&#44; J&#46;M&#46; del y Bravo Zabalgoitia&#44; G&#46;&#58; Ependimomas anapl&#225;sicos intraventriculares&#46; Neurocirug&#237;a 1994&#59; 5&#58; 32&#8211;36&#46;</p>"
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Ependimomas anaplásicos intraventriculares
G. Posadas Narro, J. Vaquero Crespo, J.M. del Pozo García, G. Bravo Zabalgoitia
Servicio de Neurocirugía. Clínica Puerta de Hierro. Universidad Autónoma de Madrid-España
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    "titulo" => "Ependimomas anapl&#225;sicos intraventriculares"
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        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se analizaron 10 pacientes con ependimomas anapl&#225;sicos&#44; hospitalizados entre enero de 1970 y diciembre de 1992&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La edad oscil&#243; entre 1 y 46 a&#241;os con un promedio de 13&#44;8 a&#241;os&#46; Siete eran hombres y 3 mujeres&#46; El tiempo de duraci&#243;n de la enfermedad fue de 2 a 24 meses&#46; En el cuadro cl&#237;nico predominaron&#58; hipertensi&#243;n endocraneal&#44; d&#233;ficit de pares craneales y s&#237;ndrome cerebeloso&#46; Siete tumores se localizaron en el IV ventr&#237;culo &#40;5 en el velo inferior y 2 en el velo superior&#41;&#44; 2 en el ventr&#237;culo lateral&#44; y 1 en el III ventr&#237;culo&#46; Todos los pacientes presentaron hidrocefalia necesitando derivaci&#243;n ventricular&#44; 5 de ellos antes de realizar la craneotom&#237;a&#46; Se realiz&#243; resecci&#243;n tumoral completa en 5 casos y parcial en otros 5&#46; Cinco pacientes recibieron radioterapia tras la cirug&#237;a y 4 de ellos radioterapia m&#225;s quimioterapia&#46; En el seguimiento de 1 a 10 a&#241;os&#44; 6 de ellos presentaban secuelas y 2 fallecieron&#44; uno por bronconeumon&#237;a y el otro por el propio tumor&#46; Tres de 5 pacientes presentaron c&#233;lulas neopl&#225;sicas en L&#46;C&#46;R&#46;&#44; y uno de estos adem&#225;s met&#225;stasis en m&#233;dula cervical de la que fue operado&#46; Un caso present&#243; meningoencefalitis por c&#225;ndida albicans&#44; resuelta con antibi&#243;ticos&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se concluye que los ependimomas anapl&#225;sicos intraventriculares se presentan preferentemente en menores de 15 a&#241;os&#44; localiz&#225;ndose fundamentalmente en el IV ventr&#237;culo&#46; Estos tumores conllevan una gran morbilidad neurol&#243;gica&#44; y el tratamiento quir&#250;rgico m&#225;s radioterapia representa la mejor actitud terap&#233;utica&#46;</p>"
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        "titulo" => "Summary"
        "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We have analyzed 10 patients with intraventricular anaplastic ependymomas studied between January 1970 and December 1992&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The age ranged from 1 to 46 years with a mean age of 13&#44;8 years&#46; Seven patients were males and 3 were females&#46; The duration of the disease ranged between 2 and 24 months&#46; Raised intracranial pressure&#44; cranial nerve deficit and cerebellar syndrome were the predominant clinical manifestations&#46; Seven of the tumors were localized in the IV ventricle &#40;5 in the inferior velum and 2 in the superior velum&#41;&#44; 2 in the lateral ventricle and 1 in the III ventricle&#46; All the patients showed hydrocephalus and it was necessary to implant a ventriculo-peritoneal CSF shunt in 5 of them before performing craneotomy&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Complete tumor resection was done in 5 cases and partial in another 5 cases&#46; It was followed by radiotherapy in 5 cases&#44; and by radiotherapy and chemotherapy in 4&#46; At follow-up&#44; ranging from 1 to 10 years&#44; 6 of the patients had neurological deficits and three of the 5 patients had neoplasic cells in the cerebral fluid&#44; and 1 developed spinal metastases&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The conclusions are that intraventricular anaplastic ependymomas predominantly occur in individuals under 15 years of age&#44; are mainly located in the IV ventricle&#44; and produce a severe neurologic morbidity&#46; Surgical treatment followed by radiotherapy improves the final prognosis of these patients&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Posadas Narro&#44; G&#46;&#59; Vaquero Crespo&#44; J&#46;&#59; Pozo Garc&#237;a&#44; J&#46;M&#46; del y Bravo Zabalgoitia&#44; G&#46;&#58; Ependimomas anapl&#225;sicos intraventriculares&#46; Neurocirug&#237;a 1994&#59; 5&#58; 32&#8211;36&#46;</p>"
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ISSN: 11301473
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