Metástasis cerebrales de melanoma
M. Clavel Escribano, P. Clavel Laria
Neurocirugía, Clínica del Pilar, Barcelona
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Clavel Laria" "autores" => array:2 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Clavel Escribano" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Clavel Laria" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Neurocirugía, Clínica del Pilar, Barcelona" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec163022" "palabras" => array:6 [ 0 => "Tumor cerebral" 1 => "Metástasis" 2 => "Melanoma" 3 => "Cirugía" 4 => "Radioterapia" 5 => "Radiocirugía" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec163023" "palabras" => array:6 [ 0 => "Brain tumor" 1 => "Metastases" 2 => "Melanoma" 3 => "Surgery" 4 => "Radiotherapy" 5 => "Stereotactic radiosurgery" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La incidencia de metástasis cerebral de melanoma maligno cutáneo se ha incrementado de forma alarmante en los últimos años, siendo la tercera metástasis más frecuente después de la de pulmón y mama.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Aunque la enfermedad tiene un mal pronóstico existen casos publicados en la bibliografía de pacientes con largas supervivencias. Esta es la situación en el primero de los pacientes presentados por nosotros en este trabajo, quien tras ser sometido a tres craneotomías, se encuentra asintomático transcurridos más de 4 años desde la primera resección quirúrgica. Presentamos otros dos pacientes, uno con evolución fulminante y otro con un curso clínico más indolente.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se realiza una revisión de la bibliografía con recomendaciones sobre la conveniencia de la cirugía en estos pacientes. Se revisa la aplicación de la radioterapia y la reciente aportación de la radiocirugía.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The incidence of metastatic malignant melanoma has experienced an important increase in the last years, becoming the third most frequent origin of cerehral metastases.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Although the disease has a poor prognosis, a few cases associated to long term survival, have been reported. We present one patient who underwent three craniotomies for resection of metastases from melanoma. More than four years after the first surgical procedure he is active and asymptomatic. Our second case suffered a fulminant course and the third a much more indolent clinical course.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A revision of the literature is made, and the criteria to be followed concerning surgical indications are considered. We also review the benefits of whole brain radiotherapy added to the surgical therapy and the recent application of the stereotactic radiosurgery.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Clavel Escribano, M.; Clavel Laria, P.: Metástasis cerebrales de melanoma. Neurocirugía 1996; 7: 275–280.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial metastatic malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.L. Bauman" 1 => "T.R. Price" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "South J. Medicine" "fecha" => "1972" "volumen" => "65" "paginaInicial" => "344" "paginaFinal" => "346" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Melanoma of the nervous system: Treatment with corticosteroids and radiation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.R. Beresford" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurology" "fecha" => "1969" "volumen" => "19" "paginaInicial" => "59" "paginaFinal" => "65" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4180158" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical treatment of brain metastases in malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K. Brega" 1 => "W.A. Robinson" 2 => "K. Winston" 3 => "W. Wittenberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1990" "volumen" => "66" "paginaInicial" => "2105" "paginaFinal" => "2110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2224765" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Brain metastasis fram melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.N. Byrne" 1 => "T.L. Cascino" 2 => "J.B. Posner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Neurol-Oncol." "fecha" => "1983" "volumen" => "1" "paginaInicial" => "313" "paginaFinal" => "317" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Value of radiation in the management of patients with cerebral metastases from malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.J. Carella" 1 => "R. Gebler" 2 => "F. Rendrickson" 3 => "H.C. Berry" 4 => "J.S. Cooper" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1980" "volumen" => "45" "paginaInicial" => "679" "paginaFinal" => "683" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6766793" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiation-induced dementia in patients cured of brain metastases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.M. De Angelis" 1 => "J.Y. Delattre" 2 => "J.B. Posner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurology" "fecha" => "1989" "volumen" => "39" "paginaInicial" => "789" "paginaFinal" => "796" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2725874" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Malignant melanoma metastatic to the central nervous system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D.R. Enzmann" 1 => "R. Kramer" 2 => "D. Norman" 3 => "J. Pollock" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/127.1.177" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1978" "volumen" => "127" "paginaInicial" => "177" "paginaFinal" => "180" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/635178" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical versus non-surgical management of metastatic melanoma of the brain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.A. Fell" 1 => "M.E. Leavens" 2 => "C.M. McBride" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery" "fecha" => "1980" "volumen" => "7" "paginaInicial" => "238" "paginaFinal" => "242" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7207741" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multiple intracranial metastases of malignant melanoma with longterm survival" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Fernández" 1 => "G. Maira" 2 => "A. Puca" 3 => "A. Vignati" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1984.60.3.0621" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg." "fecha" => "1984" "volumen" => "60" "paginaInicial" => "621" "paginaFinal" => "624" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6699709" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metastatic brain tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F.W. Gamache Jr." 1 => "J.B. Posner" 2 => "J.R. Patterson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Neurological Surgery" "paginaInicial" => "2872" "paginaFinal" => "2899" "edicion" => "2ª" "serieFecha" => "1982" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Secondary malignant melanoma of the brain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.D. Hayward" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin. Oncol." "fecha" => "1976" "volumen" => "2" "paginaInicial" => "227" "paginaFinal" => "232" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1009706" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary malignant leptomeningeal melanoma in association with giant hairy nevi. Report of two cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "H.J. Hoffman" 1 => "A. Freeman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1967.26.1part1.0062" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1967" "volumen" => "26" "paginaInicial" => "62" "paginaFinal" => "71" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6018782" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The rising incidence and mortality rate of malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.W. Kopf" 1 => "D.S. Rigel" 2 => "R.J. Friedman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J. Dermatol. Surg. Oncol." "fecha" => "1982" "volumen" => "819" "paginaInicial" => "760" "paginaFinal" => "761" "itemHostRev" => array:3 [ "pii" => "S0016508508001807" "estado" => "S300" "issn" => "00165085" ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "f Metastatic brain tumors: Results of surgical and nonsurgical treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.F. Lang" 1 => "J. Slater" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surg. Clin. North Am." "fecha" => "1964" "volumen" => "44" "paginaInicial" => "865" "paginaFinal" => "872" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14184441" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Longterm survival after removal of metastatic malignant melanoma of the brain: Report of two cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.W.P. McCann" 1 => "B.K.A. Weir" 2 => "A.R. Elridge" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1968.28.5.0483" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg." "fecha" => "1968" "volumen" => "28" "paginaInicial" => "483" "paginaFinal" => "487" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5659576" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Combination chemotherapy and hormonal therapy in the treatment of malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E.F. McClay" 1 => "M.J. Mastrangelo" 2 => "R.E. Bellet" 3 => "D. Berd" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer Treat. Rep" "fecha" => "1987" "volumen" => "71" "paginaInicial" => "465" "paginaFinal" => "469" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3567970" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term survival with recurrent metastatic intracranial melanoma: Case reporto" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.P. McNeel" 1 => "M.E. Leavens" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1968.29.1.0091" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1968" "volumen" => "29" "paginaInicial" => "91" "paginaFinal" => "93" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5674097" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Retsas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Hosp. Update" "fecha" => "1982" "volumen" => "8" "paginaInicial" => "1139" "paginaFinal" => "1146" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central nervous system involvement in malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Retsas" 1 => "A.R. Gershuny" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1988" "volumen" => "61" "paginaInicial" => "1926" "paginaFinal" => "1934" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3355984" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of metastatic malignant melanoma with recombinant interferon alfa 2 (IFN-a)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W.A. Robinson" 1 => "T.I. Mughal" 2 => "M.R. Thomas" 3 => "M. Johnson" 4 => "R.J. Spiegel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0171-2985(86)80109-7" "Revista" => array:6 [ "tituloSerie" => "Immunobiology" "fecha" => "1982" "volumen" => "172" "paginaInicial" => "275" "paginaFinal" => "282" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3804370" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastaci melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S.A. Rosenberg" 1 => "B.S. Packard" 2 => "P.M. Aebergsolds" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM198812223192527" "Revista" => array:6 [ "tituloSerie" => "N. Engl. J. Med." "fecha" => "1988" "volumen" => "319" "paginaInicial" => "1676" "paginaFinal" => "1680" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3264384" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.J. Rubinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Tumors of the central nervous system" "paginaInicial" => "328" "paginaFinal" => "332" "serieFecha" => "1972" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of metastatic brain tumors: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Sawaya" 1 => "B.L. Ligon" 2 => "A. Flowers" 3 => "R. Bindal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery Quarterly" "fecha" => "1994" "volumen" => "4" "numero" => "3" "paginaInicial" => "140" "paginaFinal" => "157" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stereotactic radiosurgery for cerebral metastatic melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Somaza" 1 => "D. Kondziolka" 2 => "L.D. Lunsford" 3 => "J.M. Kirkwood" 4 => "J.C. Flickinger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1993.79.5.0661" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg." "fecha" => "1993" "volumen" => "79" "paginaInicial" => "661" "paginaFinal" => "666" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8410244" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiation therapy for brain metastases from malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "I. Stridsklev" 1 => "O. Klepp" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Radiol. Oncol." "fecha" => "1984" "volumen" => "23" "paginaInicial" => "231" "paginaFinal" => "235" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6093438" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracerebral metastases in solid-tumor patients: Natural history and results of treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Zimm" 1 => "G.L. Wampler" 2 => "D. Stablein" 3 => "T. Hazra" 4 => "H.F. Young" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1981" "volumen" => "48" "paginaInicial" => "384" "paginaFinal" => "394" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7237407" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/11301473/0000000700000004/v1_201305151456/S1130147396710667/v1_201305151456/es/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/11301473/0000000700000004/v1_201305151456/S1130147396710667/v1_201305151456/es/main.pdf?idApp=UINPBA00004B&text.app=https://revistaneurocirugia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147396710667?idApp=UINPBA00004B" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2023 Marzo | 1 | 2 | 3 |
| 2018 Marzo | 0 | 5 | 5 |
| 2018 Febrero | 21 | 78 | 99 |
| 2018 Enero | 29 | 83 | 112 |
| 2017 Diciembre | 34 | 100 | 134 |
| 2017 Noviembre | 66 | 116 | 182 |
| 2017 Octubre | 33 | 83 | 116 |
| 2017 Septiembre | 47 | 131 | 178 |
| 2017 Agosto | 57 | 108 | 165 |
| 2017 Julio | 49 | 147 | 196 |
| 2017 Junio | 43 | 146 | 189 |
| 2017 Mayo | 21 | 159 | 180 |
| 2017 Abril | 15 | 167 | 182 |
| 2017 Marzo | 11 | 139 | 150 |
| 2017 Febrero | 4 | 195 | 199 |
| 2017 Enero | 4 | 165 | 169 |
| 2016 Diciembre | 23 | 120 | 143 |
| 2016 Noviembre | 16 | 202 | 218 |
| 2016 Octubre | 26 | 98 | 124 |
| 2016 Septiembre | 156 | 295 | 451 |
| 2016 Agosto | 284 | 338 | 622 |
| 2016 Julio | 109 | 207 | 316 |
| 2015 Diciembre | 2 | 0 | 2 |
| 2015 Agosto | 1 | 0 | 1 |
| 2015 Julio | 5 | 17 | 22 |
| 2015 Junio | 22 | 119 | 141 |
| 2015 Mayo | 15 | 144 | 159 |
| 2015 Abril | 17 | 126 | 143 |
| 2015 Marzo | 10 | 125 | 135 |
| 2015 Febrero | 19 | 163 | 182 |
| 2015 Enero | 10 | 114 | 124 |
| 2014 Diciembre | 13 | 91 | 104 |
| 2014 Noviembre | 10 | 108 | 118 |
| 2014 Octubre | 17 | 126 | 143 |
| 2014 Septiembre | 12 | 145 | 157 |
| 2014 Agosto | 16 | 154 | 170 |
| 2014 Julio | 19 | 146 | 165 |
| 2014 Junio | 15 | 143 | 158 |
| 2014 Mayo | 11 | 108 | 119 |
| 2014 Abril | 7 | 153 | 160 |
| 2014 Marzo | 13 | 141 | 154 |
| 2014 Febrero | 13 | 86 | 99 |
| 2014 Enero | 8 | 83 | 91 |
| 2013 Diciembre | 13 | 65 | 78 |
| 2013 Noviembre | 17 | 78 | 95 |
| 2013 Octubre | 13 | 74 | 87 |
| 2013 Septiembre | 23 | 90 | 113 |
| 2013 Agosto | 12 | 116 | 128 |
| 2013 Julio | 18 | 125 | 143 |
| 2013 Junio | 10 | 85 | 95 |
| 2013 Mayo | 4 | 70 | 74 |
| 2013 Abril | 10 | 55 | 65 |
| 2013 Marzo | 8 | 24 | 32 |
| 2013 Febrero | 12 | 19 | 31 |
| 2013 Enero | 11 | 26 | 37 |
| 2012 Diciembre | 12 | 21 | 33 |
| 2012 Noviembre | 2 | 12 | 14 |
| 2012 Octubre | 0 | 4 | 4 |
| 2012 Septiembre | 0 | 2 | 2 |
| 2012 Enero | 5 | 0 | 5 |
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