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array:22 [ "pii" => "S1130147397710510" "issn" => "11301473" "doi" => "10.1016/S1130-1473(97)71051-0" "estado" => "S300" "fechaPublicacion" => "1997-01-01" "aid" => "71051" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1997" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1997;8:5-15" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1764 "formatos" => array:3 [ "EPUB" => 18 "HTML" => 789 "PDF" => 957 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147397710522" "issn" => "11301473" "doi" => "10.1016/S1130-1473(97)71052-2" "estado" => "S300" "fechaPublicacion" => "1997-01-01" "aid" => "71052" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1997;8:16-24" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 12830 "formatos" => array:3 [ "EPUB" => 19 "HTML" => 2538 "PDF" => 10273 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Tratamiento no quirúrgico de los hematomas epidurales y subdurales de pequeño y mediano tamaño. Criterios para la selección y seguimiento de los pacientes" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "16" "paginaFinal" => "24" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R.D. Lobato, F. Servadei, P.A. Gómez, P. González" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R.D." "apellidos" => "Lobato" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Servadei" ] 2 => array:2 [ "nombre" => "P.A." "apellidos" => "Gómez" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "González" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397710522?idApp=UINPBA00004B" "url" => "/11301473/0000000800000001/v1_201305151458/S1130147397710522/v1_201305151458/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Valor da histopatologia e da cinética celular no prognóstico dos tumores gliais" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "5" "paginaFinal" => "15" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J. Pimentel" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Pimentel" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Laboratório de Neuropatología. Servíço de Neurología. Hospital de Santa Maria. Lisboa" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras chave" "identificador" => "xpalclavsec163061" "palabras" => array:5 [ 0 => "Gliomas" 1 => "Histopatologia" 2 => "Classificação dos gliomas" 3 => "Biópsia estereotáxica" 4 => "Cinética celular" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec163060" "palabras" => array:5 [ 0 => "Gliomas" 1 => "Histopathology" 2 => "Classification of gliomas" 3 => "Stereotactic biopsy" 4 => "Cell kinetics" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">O autor revê o valor da histopatologia e da cinética das células tumorais no prognóstico dos tumores gliais. Aspectos microscópicos como sejam a infiltração dos tecidos vizinhos ou para lá dos confins do tumor e a constatado de multifocalidade tumoral são factores importantes na recorrência dos gliomas objecto de recessóes macroscópicas totais. As classificações histopatológicas destes tumores associadas a tentativa de correlac,ao clínica sao revistas criticamente. É realçada a importância da biópsia estereotáxica no diagnóstico histológico e na opção terapêutica dos gliomas. Os métodos de avaliação prática da capacidade proliferativa das células tumorais são a determinação dos índices proliferativos do PCNA, Ki-67 e MIB1, que se correlacionam com o comportamento biológico dos gliomas.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The author reviews the value of the histology and tumor cell kinetics in the prognostic of gliomas. Microscopic features like infiltration of perilesional tissue or beyond the immediate confines of the growth, and occurrence of multifocality are important factors to tumor's recurrences after macroscopically total resections. Histopathological classifications of gliomas attempting a correlation with their prognostic are critically reviewed. The importance of stereotactic biopsy in the histological diagnosis and therapeutic approach of gliomas is stressed. The routine methods of evaluation of the proliferative capacity of tumoral cells are the PCNA, Ki-67 and MIB1 index labellings, which correlate with the clinical behaviour of gliomas.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Pimentel, J.: Valor da histopatologia e da cinética celular no prognóstico dos tumores gliais 1997; 8: 5–15.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is necrosis helpful in the grading of gliomas? Editorial opinion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E.C. Alvord Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J. Neuropathol. 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año/Mes | Html | Total | |
---|---|---|---|
2023 Marzo | 0 | 2 | 2 |
2018 Febrero | 8 | 6 | 14 |
2018 Enero | 12 | 5 | 17 |
2017 Diciembre | 19 | 4 | 23 |
2017 Noviembre | 45 | 14 | 59 |
2017 Octubre | 7 | 8 | 15 |
2017 Septiembre | 16 | 20 | 36 |
2017 Agosto | 18 | 20 | 38 |
2017 Julio | 15 | 11 | 26 |
2017 Junio | 19 | 8 | 27 |
2017 Mayo | 26 | 9 | 35 |
2017 Abril | 13 | 11 | 24 |
2017 Marzo | 13 | 0 | 13 |
2017 Febrero | 7 | 1 | 8 |
2017 Enero | 9 | 5 | 14 |
2016 Diciembre | 27 | 20 | 47 |
2016 Noviembre | 17 | 4 | 21 |
2016 Octubre | 27 | 21 | 48 |
2016 Septiembre | 38 | 9 | 47 |
2016 Agosto | 43 | 20 | 63 |
2016 Julio | 26 | 11 | 37 |
2015 Diciembre | 3 | 0 | 3 |
2015 Junio | 16 | 10 | 26 |
2015 Mayo | 19 | 17 | 36 |
2015 Abril | 11 | 18 | 29 |
2015 Marzo | 14 | 26 | 40 |
2015 Febrero | 11 | 34 | 45 |
2015 Enero | 14 | 17 | 31 |
2014 Diciembre | 10 | 25 | 35 |
2014 Noviembre | 11 | 20 | 31 |
2014 Octubre | 17 | 29 | 46 |
2014 Septiembre | 7 | 29 | 36 |
2014 Agosto | 9 | 28 | 37 |
2014 Julio | 13 | 35 | 48 |
2014 Junio | 7 | 33 | 40 |
2014 Mayo | 11 | 29 | 40 |
2014 Abril | 15 | 21 | 36 |
2014 Marzo | 8 | 25 | 33 |
2014 Febrero | 10 | 30 | 40 |
2014 Enero | 10 | 17 | 27 |
2013 Diciembre | 8 | 25 | 33 |
2013 Noviembre | 16 | 18 | 34 |
2013 Octubre | 14 | 19 | 33 |
2013 Septiembre | 12 | 22 | 34 |
2013 Agosto | 23 | 22 | 45 |
2013 Julio | 15 | 22 | 37 |
2013 Junio | 11 | 28 | 39 |
2013 Mayo | 11 | 30 | 41 |
2013 Abril | 9 | 19 | 28 |
2013 Marzo | 11 | 23 | 34 |
2013 Febrero | 7 | 23 | 30 |
2013 Enero | 15 | 9 | 24 |
2012 Diciembre | 11 | 18 | 29 |
2012 Noviembre | 0 | 15 | 15 |
2012 Octubre | 0 | 9 | 9 |
2012 Septiembre | 0 | 5 | 5 |
2012 Enero | 5 | 0 | 5 |