Avances en el tratamiento de los traumatismos craneoencefálicos graves
Advances in the management of severe head injury
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array:22 [ "pii" => "S1130147399707979" "issn" => "11301473" "doi" => "10.1016/S1130-1473(99)70797-9" "estado" => "S300" "fechaPublicacion" => "1999-01-01" "aid" => "70797" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1999" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1999;10:185-209" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4715 "formatos" => array:3 [ "EPUB" => 15 "HTML" => 1485 "PDF" => 3215 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147399707980" "issn" => "11301473" "doi" => "10.1016/S1130-1473(99)70798-0" "estado" => "S300" "fechaPublicacion" => "1999-01-01" "aid" => "70798" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1999;10:210-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3107 "formatos" => array:3 [ "EPUB" => 17 "HTML" => 1204 "PDF" => 1886 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Abordaje infratemporal preauricular a los tumores de la base del cráneo: Nuestra experiencia clínica" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "210" "paginaFinal" => "218" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Infratemporal preauricular approach to skull base tumors" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Romance, G. Sánchez Aniceto, R. Gutiérrez, R.D. Lobato, R. Alday, A. De La Lama, R. de la Mata" "autores" => array:7 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Romance" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Sánchez Aniceto" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Gutiérrez" ] 3 => array:2 [ "nombre" => "R.D." "apellidos" => "Lobato" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Alday" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "De La Lama" ] 6 => array:2 [ "nombre" => "R." "apellidos" => "de la Mata" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399707980?idApp=UINPBA00004B" "url" => "/11301473/0000001000000003/v1_201305151012/S1130147399707980/v1_201305151012/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Avances en el tratamiento de los traumatismos craneoencefálicos graves" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "185" "paginaFinal" => "209" ] ] "autores" => array:2 [ 0 => array:3 [ "autoresLista" => "J. Sahuquillo, M.A. Poca, E. Rubio" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Sahuquillo" ] 1 => array:2 [ "nombre" => "M.A." "apellidos" => "Poca" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Rubio" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía, Hospitales Universitarios Vall d’Hebron. Barcelona" ] ] ] 1 => array:3 [ "autoresLista" => "F. Munar" "autores" => array:1 [ 0 => array:3 [ "nombre" => "F." "apellidos" => "Munar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Unidad de Neurotraumatología, Hospitales Universitarios Vall d’Hebron. Barcelona" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Advances in the management of severe head injury" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156683" "palabras" => array:6 [ 0 => "Traumatismos craneoencefálicos" 1 => "Revisión" 2 => "Estrategias terapéuticas" 3 => "Corticosteroides" 4 => "Hiperventilación" 5 => "Medicina basada en la evidencia" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec156684" "palabras" => array:6 [ 0 => "Head injury" 1 => "Review" 2 => "Management strategies" 3 => "Steroids" 4 => "Hyperventilation" 5 => "Evidence-based medicine" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Los fundamentos teóricos para el tratamiento de los pacientes con un traumatismo craneoencefálico (TCE) grave se derivan del concepto de lesión secundaria. En este trabajo actualizamos las pautas de tratamiento seguidas en el traumatismo craneoencefálico y de aquel subgrupo de pacientes que presentan hipertensión intracraneaI. Introducimos el nuevo paradigma denominado medicina basada en la evidencia haciendo énfasis en sus implicaciones presentes y futuras en el tratamiento de los traumatismos craneoencefálicoso Presentamos una revisión de las recomendaciones sugeridas por las Guías de práctica clínica recientemente publicadas bajo los auspicios de la Brain Trauma Foundation. En este artículo revisamos también los grupos específicos de drogas utilizados en el tratamiento de estos pacientes y que incluyen entre otras: Sedantes y analgésicos, bloqueantes musculares, barbitúricos, corticosteroides y soluciones hiperosmolares. Planteamos las controversias existentes en el uso de algunos tratamientos tales como el aumento de la presión de perfusión cerebral mediante drogas vasoactivas, la hiperventilación o el uso de drogas tales como la dihidroergotamina y la indometacina. También presentamos una revisión histórica y las controversias existentes sobre el uso de corticosteroides y se discuten los fundamentos y la potencial utilidad de ciertas drogas dirigidas a bloquear las cascadas neuroquímicas anómalas que se han demostrado en estos pacientes. Presentamos y discutimos también las bases teóricas sobre la utilización de los 21-aminoesteroides (Lazaroides), los antagonistas del calcio, algunos fármacos potenciales protectores de membrana y los inhibidores del glutamato en el tratamiento de estos pacientes.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The theoretical basis for treatment of severe head injury derives from the concept of secondary damage to the brain. This paper provides an overview of the current therapeutic approaches used in treating severe head injury and in particular those patients who develop high intracranial pressure. Special emphasis is given to the new paradigm of so-called evidence-based medicine and its influence on the present and future management of severe head injuries. A review of the recommendations suggested by the <span class="elsevierStyleItalic">Guidelines for the Treatment of Severe Head Injury</span>, recently published by the Brain Trauma Foundation are presented. Specific types of drugs covered in this review include sedatives, analgesics, paralytic agents, barbiturates, steroids and hyperosmolar solutions. The controversies surrounding certain treatments such as the increase of cerebral perfusion pressure with vasoactive drugs, hyperventilation, indomethacine or dihydroergotamine are outlined. We also review the historical background and the controversies over the use of steroids in these patients. The recentiy developed drugs capable of blocking the damaging neurochemical cascades identified in severe head injury are discussed. Finally, the rationale for using 21-aminosteroids (Lazaroids), calcium-antagonists, potential membrane-protectors and the different types of glutamate receptors is also presented.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Sahuquillo, J.; Poca, M.A.; Munar, F.; Rubio, E.: Avances en el tratamiento de los traumatismos craneoencefálicos graves. Neurocirugía 1999; 10: 185–209.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:184 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Emergency drug therapy of closed head injury" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "CNS Drugs" "fecha" => "1995" "volumen" => "3" "paginaInicial" => "337" "paginaFinal" => "350" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular biology of the cell" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1989" "editorial" => "Garlan Publishing, lnc" "editorialLocalizacion" => "New York & London" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subtemporal decompression: radiological observations and current surgical experience" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Brit. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2023 Marzo | 2 | 4 | 6 |
| 2021 Marzo | 0 | 2 | 2 |
| 2018 Marzo | 0 | 5 | 5 |
| 2018 Febrero | 8 | 37 | 45 |
| 2018 Enero | 11 | 23 | 34 |
| 2017 Diciembre | 19 | 53 | 72 |
| 2017 Noviembre | 39 | 63 | 102 |
| 2017 Octubre | 10 | 48 | 58 |
| 2017 Septiembre | 12 | 74 | 86 |
| 2017 Agosto | 7 | 64 | 71 |
| 2017 Julio | 10 | 62 | 72 |
| 2017 Junio | 19 | 77 | 96 |
| 2017 Mayo | 22 | 66 | 88 |
| 2017 Abril | 17 | 65 | 82 |
| 2017 Marzo | 6 | 93 | 99 |
| 2017 Febrero | 8 | 125 | 133 |
| 2017 Enero | 13 | 18 | 31 |
| 2016 Diciembre | 30 | 63 | 93 |
| 2016 Noviembre | 22 | 56 | 78 |
| 2016 Octubre | 26 | 96 | 122 |
| 2016 Septiembre | 94 | 206 | 300 |
| 2016 Agosto | 156 | 161 | 317 |
| 2016 Julio | 72 | 97 | 169 |
| 2016 Febrero | 1 | 0 | 1 |
| 2015 Diciembre | 2 | 0 | 2 |
| 2015 Septiembre | 0 | 19 | 19 |
| 2015 Agosto | 2 | 0 | 2 |
| 2015 Julio | 1 | 13 | 14 |
| 2015 Junio | 16 | 68 | 84 |
| 2015 Mayo | 21 | 54 | 75 |
| 2015 Abril | 26 | 63 | 89 |
| 2015 Marzo | 23 | 35 | 58 |
| 2015 Febrero | 17 | 54 | 71 |
| 2015 Enero | 23 | 25 | 48 |
| 2014 Diciembre | 24 | 39 | 63 |
| 2014 Noviembre | 21 | 38 | 59 |
| 2014 Octubre | 31 | 62 | 93 |
| 2014 Septiembre | 29 | 67 | 96 |
| 2014 Agosto | 28 | 65 | 93 |
| 2014 Julio | 23 | 47 | 70 |
| 2014 Junio | 48 | 56 | 104 |
| 2014 Mayo | 32 | 56 | 88 |
| 2014 Abril | 23 | 65 | 88 |
| 2014 Marzo | 33 | 61 | 94 |
| 2014 Febrero | 27 | 50 | 77 |
| 2014 Enero | 29 | 53 | 82 |
| 2013 Diciembre | 18 | 57 | 75 |
| 2013 Noviembre | 33 | 53 | 86 |
| 2013 Octubre | 22 | 37 | 59 |
| 2013 Septiembre | 39 | 50 | 89 |
| 2013 Agosto | 41 | 67 | 108 |
| 2013 Julio | 39 | 63 | 102 |
| 2013 Junio | 36 | 72 | 108 |
| 2013 Mayo | 29 | 44 | 73 |
| 2013 Abril | 48 | 59 | 107 |
| 2013 Marzo | 20 | 69 | 89 |
| 2013 Febrero | 16 | 35 | 51 |
| 2013 Enero | 20 | 25 | 45 |
| 2012 Diciembre | 23 | 20 | 43 |
| 2012 Noviembre | 4 | 16 | 20 |
| 2012 Octubre | 0 | 5 | 5 |
| 2012 Septiembre | 0 | 1 | 1 |
| 2012 Enero | 16 | 0 | 16 |
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