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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La Meningioangiomatosis &#40;MA&#41; es una lesi&#243;n benigna intracraneal poco frecuente&#46; La mayor&#237;a de los casos son aislados&#44; pero tambi&#233;n se han descrito casos asociados a Neurofibromatosis &#40;NF&#41; tipo 2&#46; Los casos asociados a NF suelen ser asintom&#225;ticos&#46; Los casos no asociados a NF son sintom&#225;ticos&#44; se presentan en ni&#241;os y adultos j&#243;venes&#44; y en general afectan a leptomeninge y a corteza cerebral subyacente&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">En este trabajo se describen 2 casos no asociados a NF en ni&#241;os de 1 y 7 a&#241;os de edad&#44; que se manifestaron por crisis&#44; las cuales desaparecieron tras la extirpaci&#243;n de la lesi&#243;n&#46; Histol&#243;gicamente las lesiones eran de predominio celular en un caso y de predominio fibro-hialino en el otro&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De la revisi&#243;n de la literatura se concluye que las meningioangiomatosis no asociadas a NF suelen ser lesiones &#250;nicas&#44; cl&#237;nicamente suelen presentarse con crisis convulsivas&#44; y pueden verse asociadas a otras patolog&#237;as&#44; fundamentalmente a meningiomas&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Histol&#243;gicamente las lesiones corresponden a una proliferaci&#243;n celular de h&#225;bito meningotelial que se dispone alrededor de los vasos corticales&#46; A pesar de que todos los casos tienen caracter&#237;sticas comunes&#44; existe un amplio espectro de formas histol&#243;gicas&#44; que abarca desde casos m&#225;s celulares hasta casos m&#225;s fibrosos con calcificaciones&#46; Estas diferencias podr&#237;an corresponder a diferentes estadios evolutivos de la lesi&#243;n&#46; La extirpaci&#243;n de la lesi&#243;n conlleva la desaparici&#243;n de los s&#237;ntomas&#46;</p>"
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        "resumen" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Meningioangiomatosis &#40;MA&#41; is a rare benign intracraneal lesion&#46; The majority of cases are sporadic although the association of this lesion with familial neurofibromatosis &#40;NF&#41; type 2 is well known&#46; NF-associated MA may be multifocal and is often asymptomatic and diagnosed at autopsy&#46; Non-associated cases are usually symptomatic&#44; occurs in children and young adults and frequently arise in leptomeninges and underlying cerebral cortex&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">In the present work&#44; we describe two new non-associated cases of MA in two boys&#44; seven and one year old with seizures that disappeared after surgical excision&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Histopathologically&#44; the lesion was predominantly cellular in one case and more fibrous in the other&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">From the literature review we concluded that sporadic cases present as single lesions which manifest by seizures or persistent headaches&#46; Rarely MA has been described to coexist with meningiomas&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Histopathologically&#44; MA is characterized by a plaque-like proliferation of meningothelial and fibroblast- like cells surrounding small vessels and trapping islands of gliotic cortical tissue&#46; The lesion does not show significant atypia&#44; mitosis or necrosis&#46; Although all cases of MA share unifying features&#44; there are different degrees of histological presentation with cases predominantly cellular and others more fibrous and calcified&#46; This could correspond to different stages in the evolution of the MA&#46; Symptoms disappear with the complete excision of the lesion&#46;</p>"
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Meningioangiomatosis. Descripción de dos casos y revisión de la literatura
Meningioangiomatosis: report of two cases and literature review
A. Suárez-Gauthier, M.R. Gómez de la Bárcena, E. García-García, J.R. Ricoy
Departamentos de Anatomía Patológica/Neuropatología. Hospital Universitario 12 de Octubre. Madrid
J. Hinojosa*
*. Departamentos de Neurocirugía infantil. Hospital Universitario 12 de Octubre. Madrid

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