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Técnica no invasiva de hipertermia profunda en el tratamiento de los gliomas cerebrales. Resultados preliminares" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "118" "paginaFinal" => "123" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "A. Ley, J.Mª. Cladellas, S. Colet, P. de las Heras, R. Florensa, J. Prim, J. Roussos, A. Ariza" "autores" => array:8 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Ley" ] 1 => array:2 [ "nombre" => "J.Mª." "apellidos" => "Cladellas" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Colet" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "de las Heras" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Florensa" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Prim" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Roussos" ] 7 => array:2 [ "nombre" => "A." "apellidos" => "Ariza" ] ] ] 1 => array:2 [ "autoresLista" => "J. Calbet" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Calbet" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S113014739270894X?idApp=UINPBA00004B" "url" => "/11301473/0000000300000002/v1_201305151417/S113014739270894X/v1_201305151417/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Absceso cerebral. Revisión de 60 casos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "125" "paginaFinal" => "130" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J.M. Ortega, R. Díez Lobato, J.M. Aguado, J. Domínguez, J. Ayerbe, H. Sandoval, J.J. Rívas" "autores" => array:7 [ 0 => array:2 [ "nombre" => "J.M." "apellidos" => "Ortega" ] 1 => array:2 [ "nombre" => "R." "apellidos" => "Díez Lobato" ] 2 => array:2 [ "nombre" => "J.M." "apellidos" => "Aguado" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Domínguez" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Ayerbe" ] 5 => array:2 [ "nombre" => "H." "apellidos" => "Sandoval" ] 6 => array:2 [ "nombre" => "J.J." "apellidos" => "Rívas" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital «12 de Octubre». Madrid" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec162195" "palabras" => array:3 [ 0 => "Absceso cerebral" 1 => "tomografía computadorizada" 2 => "punción-aspiración" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec162194" "palabras" => array:3 [ 0 => "Brain abscess" 1 => "computerized tomography" 2 => "aspiration" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A pesar de los progresos en la terapia antibiótica y las técnicas radiológicas, la mortalidad del absceso cerebral es todavía importante, y su incidencia, lejos de disminuir, parece estar aumentando.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Analizamos 60 casos de absceso cerebral recogidos en nuestro Servicio entre 1974 y 1990. Las infecciones óticas y pulmonares fueron identificadas como factores predisponentes en el 30% y 12% de los casos, respectivamente. El origen de la infección no se encontró en el 35% de los pacientes.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La cefalea, la fiebre, el defecto focal y las alteraciones del nivel de conciencia fueron los síntomas de presentación más frecuentes.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El 75% de los pacientes se trataron después de la introducción de la tomografia computadorizada (TC), con un 80% de aciertos en la sospecha diagnóstica y dos días de demora entre ingreso y tratamiento. El 25% restante se manejaron antes de la era Tc, con un 50% de aciertos y ocho días de demora.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Las localizaciones más frecuentes fueron la temporal y la frontal. En el 10% de los casos los abscesos fueron múltiples. Los cultivos del pus obtenido resultaron positivos en un 75% de los casos, y los anaerobios fueron los gérmenes hallados con más frecuencia.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La mortalidad con la técnica de punción-aspiración, introducida después de la llegada de la TC, fue del 15%, mientras que con la extirpación mediante craneotomía, utilizada fundamentalmente antes de la década de los ochenta, la mortalidad fue del 50%.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Los factores pronósticos más importantes fueron la alteración del nivel de conciencia previo a la cirugía y el número de abscesos.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Despite improvements in antibiotic therapy and radiologic diagnosis, mortality caused by brain abscesses is still high, and its incidence, far from decreasing, may be rising.</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">We analyze 60 cases of brain abscess treated between 1974 and 1990. Otic and lung infections were identified as predisposing factors in 30% and 12% of the cases respectively.</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The origin of the infection was not found in the remaining 35% of the cases.</p><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Headache, fever, focal deficit and alterations in the level of consciousness were most frequent initial symptoms.</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Seventy five per cent of our patients were treated after computerized tomography (CT) introduction, when correct diagnosis was made in 80% of the cases and the average delay between admission and treatment was two days. The reamining 25% of the cases were managed during the pre-CT period, when preoperative diagnosis was made in 50% of these cases and the average delay between admission and treatment reached eight days.</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Temporal and frontal locations were the most frequent and in 10% of the cases the abscesses were multiple. Pus cultures were positive in 75% of the total sample, and anaerobes were the most commonly found germs.</p><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">The mortality rate with the aspiration surgical technique, which was introduced after CT available, was 15%, whereas it was 50% with conventional surgical excision, which was mainly used before the 1980s.</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">The most significant prognostic factars were the level of consciousness before the operation and the number of abscesses.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Ortega, J.M.; Díez Lobato, R.; Aguado, J.M.; Domínguez, J.; Ayerbe, J.; Sandoval, H.; Rivas, J.J.: Absceso cerebral. Revisión de 60 casos. Neurocirugía 1992; 3: 125–130.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:55 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fifteen-year review of the mortality of the brain abscess" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D. Alderson" 1 => "A.J. Strong" 2 => "H.R. Ingham" 3 => "J.B. Selkon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery" "fecha" => "1981" "volumen" => "8" "paginaInicial" => "1" "paginaFinal" => "6" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7010199" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." 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