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Vol. 3. Núm. 2.
Páginas 118-123 (enero 1992)
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Vol. 3. Núm. 2.
Páginas 118-123 (enero 1992)
Acceso a texto completo
Transferencia eléctrica capacitiva (TEC). Técnica no invasiva de hipertermia profunda en el tratamiento de los gliomas cerebrales. Resultados preliminares
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A. Ley, J.Mª. Cladellas, S. Colet, P. de las Heras, R. Florensa, J. Prim, J. Roussos, A. Ariza
Servicios de Neurocirugía y Anatomía Patológica del Hospital Universitario «Germans Trias i Pujol». Barcelona Badalona (Barcelona)
J. Calbet*
* Ingeniería Electrónica INDIBA, S.A. Barcelona
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Resumen

Se describe una técnica no invasiva para producir hipertermia en los tumores intracraneales mediante. Transferencia Eléctrica Capacitiva (TEC). Se presentan dos casos de glioblastoma multiorme tratados por TEC con estudio anatomopatológico y evolución clínica. Se revisa la literatura sobre los efectos de la hipertermia en las neoplasias.

Palabras clave:
Hipertermia
Transferencia Eléctrica Capacitiva (TEC)
Glioblastoma Multiforme
Summary

A new, non-invasive technique for treating intracranial tumours by producing local hyperthermia is described. The procedure is called «Transferencia eléctrica capacitiva» (T.E.C.). Two cases of glioblastoma multiforme treated by TEC are reported with a description of the pathological findings and the clinical course.

The literature on the effects of hyperthermia on intracranial neoplasms is reviewed.

Key words:
Hyperthermia
glioblastoma
intracranial tumor
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Bibliografía
[1.]
C.T. Coughlin, E.B. Douple, J.W. Strohnbehn, W.L. Eaton, B.S. Trembly, T.Z. Wong.
Interstitial hyperthermia in combination with brachytherapy.
Radiology, 148 (1983), pp. 285-288
[2.]
K.J. Henle, A.F. Bitner, L.A. Dethlefsen.
Induction of thermotolerance by multiple heat hamster ovary cells.
Cancer Res, 39 (1979), pp. 2486-2491
[3.]
J.H. Kim, E.W. Hahn.
Clinical and biological studies of localized hypertherrnia.
Cancer Res, 39 (1979), pp. 2258-2261
[4.]
H.H. Le Veen, S. Wapnick, W. Piccone, G. Falk, N. Ahmed.
Tumor eradication by radiofrecuency therapy. Response in 21 patients.
JAMA, 235 (1976), pp. 2198-2200
[5.]
M.R. Manning, T.C. Cetas, R.C. Miller, J.R. Oleson, W.G. Connor, E.W. Gerner.
Clinical hyperthennia: Results of a phase I trial employing hyperthermia alone or in combination with external beam or interstitial radiotherapy.
Cancer, 49 (1982), pp. 205-216
[6.]
J.A. Marchosky, J. Moran, N.E. Fearnot, F. Babs Ch.
Hyperthennia catheter implantation and therapy in the brain.
J. Neurosurg, 72 (1990), pp. 975-979
[7.]
J.B. Marmor, D. Pounos, T.B. Postrc, G.M. Hahn.
Treatment of superficial human neoplasms by local hyperthermia induced by ultrasound.
Cancer, 43 (1979), pp. 188-197
[8.]
E. Moriyama, N. Matsumi, T. Shiraishi, T. Tamiya, T. Satoh, K. Matsumoto, T. Furuta, A. Nishimoto.
Hyperthermia for brain tumors: Improved delivery with a new cooling system.
Neurosurgery, 2 (1988), pp. 189-195
[9.]
O.S. Nielsen, J. Overgaard.
Effect of extracellular pH on thermotolerance and recovery of hyperthermic damage in vitro.
Cancer Res, 39 (1979), pp. 2772-2778
[10.]
J. Overgaard.
Effect of hyperthermia on malignant cells in vivo. A Review and a hypothesis.
Cancer, 39 (1977), pp. 2637-2646
[11.]
J. Overgaard, H.D. Suit, A.M. Walker.
Multifractionated hyperthermia treatment of malignant and normal tissue in vivo.
Cancer Res, 4 (1980), pp. 2045-2050
[12.]
J. Overgaard.
Fractinated radiation and hyperthermia: Experimental and clinical studies.
Cancer, 48 (1981), pp. 1116-1123
[13.]
C.A. Pérez, G. Nussbaum, B. Emami, D. von Gerichten.
Clinical results of irradiation combined with local hyperthermia.
Cancer, 52 (1983), pp. 1597-1603
[14.]
R.T. Pettigrew, J.M. Galt, C.M. Ludgate, A.N. Smith.
Clinical effects of whole-body hyperthermia in advanced malignancy.
British Medical Joumal, 4 (1974), pp. 697-782
[15.]
A.V. Silberman, R.W. Rand, F.K. Storm, B. Drury, M.L. Benz, D.L. Morton.
Phase I trial for thermochemotherapy for brain malignance.
Cancer, 56 (1985), pp. 48-56
[16.]
A.V. Silberman, R.W. Rano, D.N. Krag, F.K. Storm, M. Benz, B. Drury, D.L. Morton.
Effect of localized magneticinduction hyperthermia on the brain. Temperature versus intracranial pressure.
Cancer, 57 (1986), pp. 401-404
[17.]
F.K. Storm, W.H. Harrison, R.S. Elliott, D.L. Morton.
Normal tissue and solid tumor effects of hypertherrnia in animal models and clinical trials.
Cancer Res, 39 (1979), pp. 2245-2251
[18.]
R. Tanaka, Ch.H. Kim, N. Yamada, Y. Saito.
Radiofrecuency hyperthermia for malignant brain tumors: Preliminary results of clinical trials.
Neurosurgery, 4 (1987), pp. 478-483

Ley, A.; Cladellas, J.Mª Colet, S.; de las Heras, P.; Florensa, R.; Prim, J.; Roussos, J.; Ariza, A.; Calbet, J.: Transferencia eléctrica capacitiva (TEC). Técnica no invasiva de hipertermia profunda en el tratamiento de los gliomas cerebrales. Resultados preliminares. Neurocirugía 1992; 3: 118–123.

Copyright © 1992. Sociedad Española de Neurocirugía
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