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array:23 [ "pii" => "S1130147306703438" "issn" => "11301473" "doi" => "10.1016/S1130-1473(06)70343-8" "estado" => "S300" "fechaPublicacion" => "2006-01-01" "aid" => "70343" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "2006" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2006;17:226-31" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1873 "formatos" => array:3 [ "EPUB" => 13 "HTML" => 1123 "PDF" => 737 ] ] "itemSiguiente" => array:18 [ "pii" => "S113014730670344X" "issn" => "11301473" "doi" => "10.1016/S1130-1473(06)70344-X" "estado" => "S300" "fechaPublicacion" => "2006-01-01" "aid" => "70344" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2006;17:232-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1994 "formatos" => array:3 [ "EPUB" => 15 "HTML" => 1185 "PDF" => 794 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Causas de reintervención quirúrgica en pacientes con fijación lumbar intervenidos por estenosis de canal" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "232" "paginaFinal" => "239" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Causes of reoperations in patients with lumbar spinal stenosis treated with instrumentations" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. 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"apellidos" => "Heredero" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S113014730670344X?idApp=UINPBA00004B" "url" => "/11301473/0000001700000003/v1_201305151254/S113014730670344X/v1_201305151254/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147306703426" "issn" => "11301473" "doi" => "10.1016/S1130-1473(06)70342-6" "estado" => "S300" "fechaPublicacion" => "2006-01-01" "aid" => "70342" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2006;17:215-25" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1573 "formatos" => array:3 [ "EPUB" => 16 "HTML" => 977 "PDF" => 580 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Modelos pronósticos en el traumatismo craneoencefálico grave" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "215" "paginaFinal" => "225" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prognostic models in severe head injury" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "G.R. Boto, P.A. Gómez, R.D. Lobato" "autores" => array:3 [ 0 => array:2 [ "nombre" => "G.R." "apellidos" => "Boto" ] 1 => array:2 [ "nombre" => "P.A." "apellidos" => "Gómez" ] 2 => array:2 [ "nombre" => "R.D." "apellidos" => "Lobato" ] ] ] 1 => array:2 [ "autoresLista" => "J. De la Cruz" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "De la Cruz" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147306703426?idApp=UINPBA00004B" "url" => "/11301473/0000001700000003/v1_201305151254/S1130147306703426/v1_201305151254/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Cirugia transeptoesfenoidal en adenomas hipofisarios productores de prolactina" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "226" "paginaFinal" => "231" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "O. López-Arbolay, O. Morales-Sabina, J.L. González-González, N. Valdés-Lorenzo" "autores" => array:4 [ 0 => array:3 [ "nombre" => "O." "apellidos" => "López-Arbolay" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "O." "apellidos" => "Morales-Sabina" ] 2 => array:2 [ "nombre" => "J.L." "apellidos" => "González-González" ] 3 => array:2 [ "nombre" => "N." "apellidos" => "Valdés-Lorenzo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital Clínico Quirúrgico “Hermanos Ameijeiras”. Ciudad de la Habana. Cuba" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia postal: San Lázaro 701. 10300 Centro Habana. Ciudad de la Habana. Cuba." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Transsphenoidal approach to prolactinomas" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-04-08" "fechaAceptado" => "2005-05-19" "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Para un gran número de tumores pituitarios, la cirugía es el tratamiento de primera línea y el abordaje transesfenoidal microquirúrgico el proceder más utilizado. El tratamiento actual de los prolactinomas es bastante controversial, por los buenos resultados alcanzados con los nuevos agonistas dopaminérgicos; no obstante la adenomectomía selectiva se incluye entre las modalidades de tratamiento para aquellos prolactinomas que no respondan a dicho tratamiento dopaminérgico.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Evaluar los resultados del tratamiento microquirúrgico por vía transeptoesfenoidal de los adenomas productores de prolactina en el Servicio de Neurocirugía del Hospital “Hermanos Ameijeiras”.</p> <span class="elsevierStyleSectionTitle">Material y método</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos un estudio retrospectivo y descriptivo de 63 pacientes intervenidos por vía sublabial transeptoesfenoidal microquirúrgica, portadores de este tipo de adenomas, y tratados en nuestro servicio desde 1996 hasta el 2003. Se analizan edad, sexo, cuadro clínico, tamaño de las lesiones, niveles hormonales, complicaciones y evolución postoperatoria.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se encontró un franco predominio del sexo femenino, 86% (54 pacientes). Se operaron 31 pacientes con macroadenomas y 32 con microadenomas. La complicación más común en el postoperatorio fue la diabetes insípida transitoria (11 enfermos), siendo de poca trascendencia. Se logró reducir las cifras iniciales de prolactina a valores no tumorales en el 90.6% de lo microadenomas (29 casos) y en el 67.7% de los macroadenomas (21 casos). Los síntomas más frecuentes que aquejaban a nuestros pacientes mejoraron, sobre todo la cefalea en el 82% (36 casos) y los trastornos visuales en el 69% (18 casos).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Se concluye que la adenomectomía transeptoesfenoidal es un proceder seguro y eficaz como opción de tratamiento para pacientes con adenomas secretores de prolactina que tengan indicación quirúrgica.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Transeptal transsphenoidal surgery for pituitary tumors is a well established surgical technique. In particular the use of medical treatment in patient with prolactinomas has induced the control of hiperprolactinemia and the shrinkage of the tumor in the great majority of the patients, for that reason the treatment of the prolactinomas is controversial.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">We evaluate the results of trassphenoidal microsurgical treatment of prolactin secreting adenomas at our Unit.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">We made a retrospective analysis of 63 patients operated on via transsphenoidal microsurgical technique for prolactin secreting adenomas between 1996 and 2003. Age, sex, symptoms, tumor size, hormonal levels, complications and postsurgical outcome werw considered.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">There was a female predominance of 86% of the cases and middle aged patients were more commonly seen 31 patients had tumors more than 10mm in diameter on the CT scan. The most frecuent complication was transient diabetes insipidus (11 cases). Prolactin levels were reduced to non tumoral values in 90.6% of microadenomas (29 cases) and in 67.7% of macroadenomas (21 cases). Headache was the most frecuent complain in our patients with amelioration after surgery in 82% (36 cases). Campimetric visual defects werw reduced in 69% (18 cases).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Transsphenoidal adenomectomy is a safe treatment option for patients with prolactin secreting adenomas with surgical indication.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">López-Arbolay, O.; Morales-Sabina, O.; González-González, J.L.; Valdés-Lorenzo, N.: Cirugía transeptoesfenoidal en adenomas hipofisarios productores de prolactina. Neurocirugía 2006; 17: 226–231.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:25 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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