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array:23 [ "pii" => "S1130147396710783" "issn" => "11301473" "doi" => "10.1016/S1130-1473(96)71078-3" "estado" => "S300" "fechaPublicacion" => "1996-01-01" "aid" => "71078" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1996" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1996;7:189-92" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3127 "formatos" => array:3 [ "EPUB" => 22 "HTML" => 1023 "PDF" => 2082 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147396710795" "issn" => "11301473" "doi" => "10.1016/S1130-1473(96)71079-5" "estado" => "S300" "fechaPublicacion" => "1996-01-01" "aid" => "71079" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1996;7:193-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2411 "formatos" => array:3 [ "EPUB" => 18 "HTML" => 906 "PDF" => 1487 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Síndrome de túnel carpiano experiencia en 124 pacientes" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "193" "paginaFinal" => "198" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "A. 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"apellidos" => "Jiménez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147396710795?idApp=UINPBA00004B" "url" => "/11301473/0000000700000003/v1_201305151453/S1130147396710795/v1_201305151453/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147396710771" "issn" => "11301473" "doi" => "10.1016/S1130-1473(96)71077-1" "estado" => "S300" "fechaPublicacion" => "1996-01-01" "aid" => "71077" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1996;7:181-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1635 "formatos" => array:3 [ "EPUB" => 14 "HTML" => 808 "PDF" => 813 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Traumatismos medulares experimentales: Revisión de la literatura y descripción de un modelo mediante compresión mantenida en la rata" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "181" "paginaFinal" => "188" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "M.A. Pérez-Espejo, M. Poza y Poza" "autores" => array:2 [ 0 => array:2 [ "nombre" => "M.A." "apellidos" => "Pérez-Espejo" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Poza y Poza" ] ] ] 1 => array:2 [ "autoresLista" => "S.S. Haghighi, J.J. Oró" "autores" => array:2 [ 0 => array:2 [ "nombre" => "S.S." "apellidos" => "Haghighi" ] 1 => array:2 [ "nombre" => "J.J." "apellidos" => "Oró" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147396710771?idApp=UINPBA00004B" "url" => "/11301473/0000000700000003/v1_201305151453/S1130147396710771/v1_201305151453/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Efectos de la administración de dexametasona sobre un modelo experimental de tumor neuroectodérmico primitivo" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "189" "paginaFinal" => "192" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "M. Zurita, S. Oya, S. Coca, J. Vaquero" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Zurita" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Oya" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Coca" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Vaquero" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Laboratorio de Neuro-oncología experimental, Servicio de Neurocirugía, Hospital Universitario Clínica Puerta de Hierro; Departamentos de Biología Celular y Anatomía Patológica, Facultad de Medicina, Universidad Complutense, Madrid" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec162990" "palabras" => array:3 [ 0 => "Tumor neuroectodérmico primitivo" 1 => "Dexametasona" 2 => "Tumor cerebral experimental" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec162989" "palabras" => array:3 [ 0 => "Primitive neuroectodermal tumor" 1 => "Dexamethasone" 2 => "Experimental brain tumor" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio experimental sobre el tumor IL-7, implantado subcutáneamente en ratas Wistar, al objeto de verificar si la administración sistémica o intralesional de dexametasona puede ejercer un efecto antitumoral. Los resultados obtenidos muestran que, tras cuatro semanas de tratamiento, la administración de este fármaco, ya sea por vía sistémica o mediante inyección directa intratumoral, no modifica significativamente el volumen del tumor ni el índice de proliferación celular. Teniendo en cuenta el carácter neuroectodérmico primitivo del tumor IL-7, los presentes resultados sugieren la ineficacia de la dexametasona, como agente citolítico, sobre neoplasias cerebrales humanas que muestren características histológicas de tumor neuroectodérmico primitivo.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An experimental study has been performed on the IL-7 tumor growing in the subcutaneous tissue of Wistar rats. The possibility of an antitumor effect of dexamethasone, after systemic or intralesional administration was evaluated. After four weeks of dexamethasone administration, a reduction in the tumor volume or proliferation cell index was not reached. Due to the fact that IL-7 may be considered as a primitive neuroectodermal tumor, our present results suggest that dexamethasone is inefficacious as a cytolytic agent for the control of human primitive neuroectodermal tumors.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Zurita, M.; Oya, S.; Coca, S.; Vaquero, J.: Efectos de la administración de dexametasona sobre un modelo experimental de tumor neuroectodérrnico primitivo. Neurocirugía 1996; 7: 189–192.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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