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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Los recientes avances en radiolog&#237;a&#44; t&#233;cnica microquir&#250;rgica y de reconstrucci&#243;n han permitido que la cirug&#237;a craneofacial &#40;CCF&#41; se haya convertido en el tratamiento de elecci&#243;n de la patolog&#237;a tumoral de fosa craneal anterior&#46; A pesar de esto&#44; continua asoci&#225;ndose a una incidencia de complicaciones considerable &#40;24&#8211;56&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">&#46; Revisi&#243;n&#44; an&#225;lisis y manejo de las complicaciones de la CCF en una serie de 41 pacientes&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">41 pacientes diagnosticados de patolog&#237;a tumoral infiltrativa de base craneal anterior&#44; fueron intervenidos mediante CCF&#44; entre 1990 y 2002&#46; La extensi&#243;n tumoral fue valorada en todos los casos con TC y RMN de la regi&#243;n craneo-facial&#46; Tras determinar el volumen y extensi&#243;n tumoral se dise&#241;&#243; un tratamiento quir&#250;rgico radical&#44; con el objetivo de conseguir una resecci&#243;n tumoral &#8220;en bloque&#8221;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El 63&#46;4&#37; de los pacientes eran varones con una mediana de edad de 57 a&#241;os &#40;18&#8211;73&#41;&#46; La histolog&#237;a m&#225;s frecuente de los tumores fue carcinoma escamoso y la localizaci&#243;n habitual fue en los senos paranasales en el 78&#37; &#40;32 de 41 casos&#41;&#46; En el 85&#46;4&#37; de los pacientes se realiz&#243; una craneotom&#237;a bifrontal basal y en el 14&#46;6&#37; restante craneotom&#237;a frontoorbitaria unilateral&#44; en un s&#243;lo colgajo &#243;seo&#46; El &#225;rea de resecci&#243;n facial inclu&#237;a&#58; etmoidectom&#237;a &#40;60&#46;9&#37;&#41;&#44; etmoido-esfenoidectom&#237;a &#40;24&#46;3&#37;&#41;&#44; maxilectom&#237;a unilateral &#40;39&#37;&#41; y exenteraci&#243;n orbitaria &#40;14&#46;6&#37;&#41;&#46; Para la reconstrucci&#243;n se utiliz&#243;&#58; colgajo pediculado pericraneal &#40;100&#37;&#41;&#44; colgajos locales &#40;34&#46;1&#37;&#41;&#44; colgajos libres microvascularizados &#40;21&#46;9&#37;&#41; e injerto &#243;seo aut&#243;logo &#40;19&#46;5&#37;&#41;&#46; 20 pacientes &#40;48&#46;7&#37;&#41; presentaron complicaciones postoperatorias&#44; entre las que destacan&#44; como complicaciones mayores la f&#237;stula de LCR &#40;12&#46;1&#37;&#41; y la meningitis &#40;7&#46;3&#37;&#41;&#46; La mortalidad global fue del 7&#46;3&#37;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La CCF continua asoci&#225;ndose a una elevada tasa de complicaciones&#44; en general de tipo infeccioso&#46; El perfeccionamiento de las t&#233;cnicas de reconstrucci&#243;n permitir&#225;n reducir la incidencia de las complicaciones m&#225;s frecuentes y peligrosas&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The development of new radiographic techniques and the refinement of microsurgery and reconstructive surgery have been the responsible of the establishment of craniofacial resection &#40;CFR&#41; as the standard treatment of anterior skull base tumors&#46; Overall complication rates varies from 24&#8211;56&#37;&#44; according to a review of recently published series&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">&#46; To describe the complications of CFR in a series of 41 patients and to analyze the management and final outcome&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">From 1990 to 2002&#44; 41 patients underwent CFR for tumors involving the anterior cranial base&#46; The extent of the tumor was always assessed with craniofacial CT-scan and MRI&#46; The objective of the surgical treatment was to achive &#8220;on block&#8221; removal of the tumor&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The average age was 57 years with a male preponderance &#40;63&#46;4&#37;&#41;&#46; Squamous cell carcinoma was the most frequent histopathological type of tumor&#46; The tumors were localized in paranasal sinuses in 78&#37; of the cases&#46; Bifrontal craniotomy was performed in 85&#46;4&#37; and unilateral orbitofrontal craniotomy in 14&#46;6&#37; of the cases&#46; The area of facial resection included&#58; ethmoidectomy &#40;60&#46;9&#37;&#41;&#44; ethmoido-sphenoidectomy &#40;24&#46;3&#37;&#41;&#44; maxillectomy &#40;39&#37;&#41; and orbital exenteration &#40;14&#46;6&#37;&#41;&#46; The reconstruction of the floor of the anterior cranial fossa was performed using pedicled pericranial flap &#40;100&#37;&#41;&#44; local &#40;34&#46;1&#37;&#41; or microvascular free flaps &#40;21&#46;9&#37;&#41; and split calvarian graft &#40;19&#46;5&#37;&#41;&#46; 20 patients &#40;48&#46;7&#37;&#41; developed post-operative complications&#44; CSF leaks &#40;12&#46;1&#37;&#41; and meningitis &#40;7&#46;3&#37;&#41; being the most frequent major complications&#46; The mortality rate was 7&#46;3&#37;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">CFR has become the standard approach for anterior cranial base tumors&#46; Despite its widespread application&#44; the complication&#39;s rate ranges between 24&#8211;50&#37; and the procedure carries a risk of significant morbidity and even mortality&#46; Improvement of specific aspects of surgical technique and more refined reconstructive methods will decrease the number of complications&#46;</p>"
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Complicaciones de la cirugía craneofacial en tumores de base craneal anterior
Complications of craniofacial resection in anterior skull base tumors
A. Torres
, J.J. Acebes, L. López, A. Marnov
Servicios de Neurocirugía. Hospital Universitario de Bellvitge. Barcelona
J. Viñals*, J.M. Serra*, M. Maños**, A. Monner***
* Servicios de Cirugía Plástica. Hospital Universitario de Bellvitge. Barcelona
** Servicios de ORL. Hospital Universitario de Bellvitge. Barcelona
*** Servicios de Cirugía Maxilofacial. Hospital Universitario de Bellvitge. Barcelona
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The development of new radiographic techniques and the refinement of microsurgery and reconstructive surgery have been the responsible of the establishment of craniofacial resection &#40;CFR&#41; as the standard treatment of anterior skull base tumors&#46; Overall complication rates varies from 24&#8211;56&#37;&#44; according to a review of recently published series&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">&#46; To describe the complications of CFR in a series of 41 patients and to analyze the management and final outcome&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">From 1990 to 2002&#44; 41 patients underwent CFR for tumors involving the anterior cranial base&#46; The extent of the tumor was always assessed with craniofacial CT-scan and MRI&#46; The objective of the surgical treatment was to achive &#8220;on block&#8221; removal of the tumor&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The average age was 57 years with a male preponderance &#40;63&#46;4&#37;&#41;&#46; Squamous cell carcinoma was the most frequent histopathological type of tumor&#46; The tumors were localized in paranasal sinuses in 78&#37; of the cases&#46; Bifrontal craniotomy was performed in 85&#46;4&#37; and unilateral orbitofrontal craniotomy in 14&#46;6&#37; of the cases&#46; The area of facial resection included&#58; ethmoidectomy &#40;60&#46;9&#37;&#41;&#44; ethmoido-sphenoidectomy &#40;24&#46;3&#37;&#41;&#44; maxillectomy &#40;39&#37;&#41; and orbital exenteration &#40;14&#46;6&#37;&#41;&#46; The reconstruction of the floor of the anterior cranial fossa was performed using pedicled pericranial flap &#40;100&#37;&#41;&#44; local &#40;34&#46;1&#37;&#41; or microvascular free flaps &#40;21&#46;9&#37;&#41; and split calvarian graft &#40;19&#46;5&#37;&#41;&#46; 20 patients &#40;48&#46;7&#37;&#41; developed post-operative complications&#44; CSF leaks &#40;12&#46;1&#37;&#41; and meningitis &#40;7&#46;3&#37;&#41; being the most frequent major complications&#46; The mortality rate was 7&#46;3&#37;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">CFR has become the standard approach for anterior cranial base tumors&#46; Despite its widespread application&#44; the complication&#39;s rate ranges between 24&#8211;50&#37; and the procedure carries a risk of significant morbidity and even mortality&#46; Improvement of specific aspects of surgical technique and more refined reconstructive methods will decrease the number of complications&#46;</p>"
      ]
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    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Torres&#44; A&#46;&#59; Acebes&#44; J&#46;J&#46;&#59; L&#243;pez&#44; L&#46;&#59; Marnov&#44; A&#46;&#59; Vi&#241;als&#44; J&#46;&#59; Serra&#44; J&#46;M&#46;&#59; Ma&#241;osa&#44; M&#46;&#59; Monner&#44; A&#46;&#58; Complicaciones de la cirug&#237;a craneofacial en tumores de base craneal anterior&#46; Neurocirug&#237;a 2005&#59; 16&#58;492&#8211;498&#46;</p>"
      ]
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                      "autores" => array:1 [
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                          "etal" => false
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                            0 => "R&#46; Guti&#233;rrez D&#237;az"
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                      "autores" => array:1 [
                        0 => array:2 [
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
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                        0 => array:2 [
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                            0 => "F&#46; Lesoin"
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                        0 => array:2 [
                          "etal" => false
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                            0 => "R&#46;D&#46; Lobato"
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