Mecanismos de la estimulación medular sobre el tono vasomotor. Estudio experimental en la rata
J.M. González-Darder, E. Gómez-Cárdenas, J.L. Gil-Saló
Departamento de Cirugía (Neurocirugía). Facultad de Medicina. Universidad de Cádiz
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"apellidos" => "Maillo" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147390709360?idApp=UINPBA00004B" "url" => "/11301473/0000000100000006/v1_201305151002/S1130147390709360/v1_201305151002/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Mecanismos de la estimulación medular sobre el tono vasomotor. Estudio experimental en la rata" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "391" "paginaFinal" => "395" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J.M. González-Darder, E. Gómez-Cárdenas, J.L. Gil-Saló" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J.M." "apellidos" => "González-Darder" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Gómez-Cárdenas" ] 2 => array:2 [ "nombre" => "J.L." "apellidos" => "Gil-Saló" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Cirugía (Neurocirugía). Facultad de Medicina. Universidad de Cádiz" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156579" "palabras" => array:3 [ 0 => "Estimulación eléctrica medular" 1 => "control vasomotor" 2 => "rata" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec156580" "palabras" => array:3 [ 0 => "Spinal cord stimulation" 1 => "vasomotor control" 2 => "rat" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Con la finalidad de contribuir al estudio de los mecanismos de la estimulación eléctrica medular (EEM) sobre el tono vasomotor se ha diseñado un estudio experimental en el que se mide la presión arterial media (PAM) de la rata sometida a estimulación medular. Se han construido tres grupos experimentales de control variando las características de la estimulación, obteniendo en todos ellos una reducción de la PAM. Otros grupos de animales fueron tratados farmacológicamente antes de la estimulación con drogas que activan o bloquean los más importantes mecanismos de control vasomotor. También se estudiaron anillos de aorta de rata normal, previamente contraídos con noradrenalina, en un baño de órganos frente a la acción de suero procedente de ratas «sham» y estimuladas. Nuestros resultados permiten confirmar el efecto vasodilatador de la EEM y que el mismo se consigue por la acción sobre los efectores más periféricos del tono vasomotor y por la activación de múltiples mecanismos.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An experimental study has been designed to study the mechanisms of spinal cord stimulation (SCS) on the vasomotor control. Blood pressure changes were monitoreds in rats submited to SCS. Three control groups, by using different parameters of SCS, were done. In all groups SCS reduced the mean arterial blood pressure. In other experimental groups, the main systems involved in vasomotor control were pharmacologically blocked or activated before SCS. Also rings of aortic arteries of normal rats, precontracted by addition of noradrenaline, were studied «in vitro» in an bath organ against serum from sham and stimulated rats. The results of our experimental study suggest: SCS has a vasodilatory effect; the action of SCS is done in the most peripheral effectors of the vasomotor control; and, finally, the action of SCS is mediated by multiple mechanisms.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">González-Darder, J. M.; Gómez-Cárdenas, E.; Gil-Salú, J. L.: Mecanismos de la estimulación medular sobre el tono vasomotor. Estudio experimental en la rata. Neurocirugía, 1990; 1: 391–395.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidural electrical stimulation in severe limb ischemia. Evidence of pain relief, increase blood flow and possible limb-saving effect" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.E. Auoustinsson" 1 => "C.A. Carlsson" 2 => "M. Fall" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann. Surg." 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