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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El t&#233;rmino meningioma secretor corresponde a un subtipo de meningioma cuyas caracter&#237;sticas histopatol&#243;gicas est&#225;n representadas por un patr&#243;n sincitial&#44; presencia difusa de inclusiones hialinas e hiperplasia pericitaria focal&#46; Los hallazgos ultraestructurales e inmunohistoqu&#237;micos revelan la m&#225;xima expresi&#243;n de la conocida bipotencialidad&#44; mesenquimal y epitelial&#44; del meningioma&#46; Estas peculiaridades morfol&#243;gicas se acompa&#241;an de una mayor rapidez de presentaci&#243;n cl&#237;nica y un intenso edema peritumoral&#44; que lo hace dif&#237;cilmente reconocible como meningioma&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El hallazgo de ant&#237;geno carcinoembrionario &#40;CEA&#41; a nivel del tejido tumoral apunta la posibilidad de utilizar este marcador a nivel s&#233;rico y de LCR en el seguimiento de estos enfermos&#44; as&#237; como incluir al meningioma secretor en el diagn&#243;stico diferencial de pacientes con niveles de CEA elevados&#46;</p>"
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        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Secretory meningioma is the term given to a kind of meningioma characterized histologically by a meningothelial growth pattern&#44; the presence of hyaline inclusions diffusely distributed throughout the tumour and focal pericytic hyperplasia&#46; Ultrastructural and inmunohistochemical findings show the highest occurrence of the well-know bipotential capability of differentiation &#8212;epithelial and mesenchymal&#8212; of meningiomas&#46; This tumour is often accompanied by cerebral edema and a rapid evolution of symptons&#44; making the clinical diagnosis of meningioma difficult&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The positive staining of neoplastic cells for carcinoembrionic antigen &#40;CEA&#41; suggests the possibility of using this marker not only in the serum but also in the C&#46;S&#46;F&#46; for the follow-up of patients harboring secretory meningioma&#44; and stresses the necessity of including this tumour in the differential diagnosis of patients with a high level of CEA in their sera&#46;</p>"
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Meningioma secretor. Correlación clínicopatológica y revisión de la literatura
T. Alvaro, D. Aguilar, J. Aneiros, M.A. Arraez, J.M. Martín, M. Gómez-Morales, R. García del Moral
Departamento de Anatomía Patológica. Hospital Clínico Universitario. Granada
Servicio de Neurocirugía. Hospital Virgen de las Nieves. Granada
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El t&#233;rmino meningioma secretor corresponde a un subtipo de meningioma cuyas caracter&#237;sticas histopatol&#243;gicas est&#225;n representadas por un patr&#243;n sincitial&#44; presencia difusa de inclusiones hialinas e hiperplasia pericitaria focal&#46; Los hallazgos ultraestructurales e inmunohistoqu&#237;micos revelan la m&#225;xima expresi&#243;n de la conocida bipotencialidad&#44; mesenquimal y epitelial&#44; del meningioma&#46; Estas peculiaridades morfol&#243;gicas se acompa&#241;an de una mayor rapidez de presentaci&#243;n cl&#237;nica y un intenso edema peritumoral&#44; que lo hace dif&#237;cilmente reconocible como meningioma&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El hallazgo de ant&#237;geno carcinoembrionario &#40;CEA&#41; a nivel del tejido tumoral apunta la posibilidad de utilizar este marcador a nivel s&#233;rico y de LCR en el seguimiento de estos enfermos&#44; as&#237; como incluir al meningioma secretor en el diagn&#243;stico diferencial de pacientes con niveles de CEA elevados&#46;</p>"
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ISSN: 11301473
Idioma original: Español
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