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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Pese a los avances de la neurorradiolog&#237;a&#44; el manejo preciso de ciertos enfermos con procesos expansivos intracraneales depende con frecuencia del conocimiento de su diagn&#243;stico histol&#243;gico&#46; En el presente trabajo&#44; se analiza el empleo de las t&#233;cnicas estereot&#225;xicas en el diagn&#243;stico y tratamiento de 174 pacientes con este tipo de patolog&#237;a&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El criterio de selecci&#243;n fue valorado mediante los datos de la historia cl&#237;nica&#44; exploraci&#243;n neurol&#243;gica&#44; estudios neurorradiol&#243;gicos y&#44; en el caso de los candidatos a cirug&#237;a&#44; se consider&#243; su riesgo vital y funcional&#46; En todos los pacientes fue realizada una biopsia estereot&#225;xica&#46; En el 85&#44;06&#37; de los enfermos fue suficiente un blanco&#44; obteni&#233;ndose un diagn&#243;stico histol&#243;gico positivo en el 92&#44;53&#37; de los casos&#46; En 44&#44; la t&#233;cnica estereot&#225;xica sirvi&#243; no s&#243;lo para obtener un diagn&#243;stico citol&#243;gico&#44; sino tambi&#233;n para vaciar una cavidad qu&#237;stica &#40;tumoral o abscesificada&#41; o realizar tratamientos braquiter&#225;picos&#46; La evoluci&#243;n postbi&#243;psica de los pacientes fue excelente en 32 &#40;18&#44;39&#37;&#41; y sin cambios en 136 &#40;78&#44;16&#37;&#41; de los casos&#46; Uno de los pacientes muri&#243;&#44; lo que corresponde a una mortalidad del 0&#44;57&#37;&#46; La morbilidad transitoria fue del 2&#44;87&#37; &#40;5 casos&#41;&#46; No hemos tenido morbilidad permanente&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Para determinar la eficacia de la metodolog&#237;a estereot&#225;xica&#44; se evalu&#243; la relaci&#243;n entre nuestros diagn&#243;sticos de presunci&#243;n y los resultados histol&#243;gicos comprobados en 149 casos&#46; S&#243;lo el 58&#44;39&#37; fue diagnosticado correctamente antes de la biopsia&#46; En otro 12&#44;75&#37; hubo diferencias en cuanto al grado de anaplasia tumoral y en el 28&#44;86&#37; restante los diagn&#243;sticos fueron incorrectos&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La angiograf&#237;a nos ha sido muy &#250;til para localizar el blanco y para evitar la hemorragia intraoperatoria&#46; La monitorizaci&#243;n de la impedancia tisular ha facilitado una informaci&#243;n importante sobre el trayecto y situaci&#243;n de la aguja&#44; de acuerdo con la residencia tisular encontrada y los cortes del TAC&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">En nuestra experiencia&#44; las t&#233;cnicas estereot&#225;xicas representan un camino racional para obtener diagn&#243;sticos m&#225;s precisos y una alternativa para evitar el manejo a ciegas de una parte importante de la patolog&#237;a intracraneal&#46;</p>"
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        "resumen" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The management of certain intracranial processes still depends upon a histological diagnosis despite advances in neuroradiology&#46; We analyzed the usefulness of the stereotactic technique in the diagnosis and treatment of 174 patients harbouring intracranial processes&#46; The selection criteria was evaluated by history&#44; neurological examination&#44; neuroradiological studies&#44; and in the case of surgical candidates&#44; by their vital and functional risks&#46; In all our patients a stereotactic biopsy was performed&#46; One target was enough in 85&#44;06&#37;&#44; and a positive histological diagnosis was obtained in 92&#44;53&#37;&#46; In 44 out of our 174 cases the stereotactic system was used not only to obtain a cytological diagnosis but also to deflate a cyst cavity &#40;tumoral or abscess&#41; or to insert or remove a radioactive isotope&#46; The patient&#39;s postbiopsy course was excellent in 32 &#40;18&#44;39&#37;&#41; and unchanged in 136 &#40;78&#44;16&#37;&#41;&#46; One patient died&#44; which corresponds to a mortality rate of 0&#44;57&#37;&#46; The transitory morbidity was 2&#44;87&#37; &#40;5 cases&#41;&#46; No permanent morbidity was noted&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To determine the efficiency of our stereotactic methodology we evaluated the relationship between our presumptive diagnosis from the cl&#237;nical and neuroradiological studies and the final histological results&#46; The presumptive diagnosis was confirmed in 58&#44;39&#37;&#44; in 12&#44;75&#37; the differences were in the degree of tumor anaplasia and in 28&#44;86&#37; our diagnosis was incorrect&#46; Angiography was considered very useful in localizing the target and in avoiding intraoperative haemorrhage&#46; Impedance monitoring gave us important information regarding the trajectory and depth of the target according to the tissue resistance encountered&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">From our experience&#44; we think that stereotactic techniques represent an alternative to blind management of an important part of intracranial pathology&#44; and a rational way to obtain a more accurate diagnosis&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Hern&#225;ndez Vicente J&#46;&#59; Morales Ramos F&#46;&#59; Santos Briz A&#46;&#59; Maillo S&#225;nchez A&#46;&#59; G&#243;mez-Moreta J&#46; A&#46;&#59; D&#237;az Cascajo P&#46;&#58; Empleo de la biopsia estereot&#225;xica en pacientes con procesos expansivos intracraneales&#46; Neurocirug&#237;a&#44; 1991&#59; 2&#58; 87&#8211;94&#46;</p>"
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Empleo de la biopsia estereotáxica en pacientes con procesos expansivos intracraneales
J. Hernández Vicente, F. Morales Ramos, A. Maillo Sánchez, J.A. Gómez-Moreta, P. Díaz Cascajo
Servicios de Neurocirugía. Hospital Virgen de la Vega
A. Santos Briz*
* Servicios de Anatomía Patológica. Hospital Virgen de la Vega
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Pese a los avances de la neurorradiolog&#237;a&#44; el manejo preciso de ciertos enfermos con procesos expansivos intracraneales depende con frecuencia del conocimiento de su diagn&#243;stico histol&#243;gico&#46; En el presente trabajo&#44; se analiza el empleo de las t&#233;cnicas estereot&#225;xicas en el diagn&#243;stico y tratamiento de 174 pacientes con este tipo de patolog&#237;a&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El criterio de selecci&#243;n fue valorado mediante los datos de la historia cl&#237;nica&#44; exploraci&#243;n neurol&#243;gica&#44; estudios neurorradiol&#243;gicos y&#44; en el caso de los candidatos a cirug&#237;a&#44; se consider&#243; su riesgo vital y funcional&#46; En todos los pacientes fue realizada una biopsia estereot&#225;xica&#46; En el 85&#44;06&#37; de los enfermos fue suficiente un blanco&#44; obteni&#233;ndose un diagn&#243;stico histol&#243;gico positivo en el 92&#44;53&#37; de los casos&#46; En 44&#44; la t&#233;cnica estereot&#225;xica sirvi&#243; no s&#243;lo para obtener un diagn&#243;stico citol&#243;gico&#44; sino tambi&#233;n para vaciar una cavidad qu&#237;stica &#40;tumoral o abscesificada&#41; o realizar tratamientos braquiter&#225;picos&#46; La evoluci&#243;n postbi&#243;psica de los pacientes fue excelente en 32 &#40;18&#44;39&#37;&#41; y sin cambios en 136 &#40;78&#44;16&#37;&#41; de los casos&#46; Uno de los pacientes muri&#243;&#44; lo que corresponde a una mortalidad del 0&#44;57&#37;&#46; La morbilidad transitoria fue del 2&#44;87&#37; &#40;5 casos&#41;&#46; No hemos tenido morbilidad permanente&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Para determinar la eficacia de la metodolog&#237;a estereot&#225;xica&#44; se evalu&#243; la relaci&#243;n entre nuestros diagn&#243;sticos de presunci&#243;n y los resultados histol&#243;gicos comprobados en 149 casos&#46; S&#243;lo el 58&#44;39&#37; fue diagnosticado correctamente antes de la biopsia&#46; En otro 12&#44;75&#37; hubo diferencias en cuanto al grado de anaplasia tumoral y en el 28&#44;86&#37; restante los diagn&#243;sticos fueron incorrectos&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La angiograf&#237;a nos ha sido muy &#250;til para localizar el blanco y para evitar la hemorragia intraoperatoria&#46; La monitorizaci&#243;n de la impedancia tisular ha facilitado una informaci&#243;n importante sobre el trayecto y situaci&#243;n de la aguja&#44; de acuerdo con la residencia tisular encontrada y los cortes del TAC&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">En nuestra experiencia&#44; las t&#233;cnicas estereot&#225;xicas representan un camino racional para obtener diagn&#243;sticos m&#225;s precisos y una alternativa para evitar el manejo a ciegas de una parte importante de la patolog&#237;a intracraneal&#46;</p>"
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        "resumen" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The management of certain intracranial processes still depends upon a histological diagnosis despite advances in neuroradiology&#46; We analyzed the usefulness of the stereotactic technique in the diagnosis and treatment of 174 patients harbouring intracranial processes&#46; The selection criteria was evaluated by history&#44; neurological examination&#44; neuroradiological studies&#44; and in the case of surgical candidates&#44; by their vital and functional risks&#46; In all our patients a stereotactic biopsy was performed&#46; One target was enough in 85&#44;06&#37;&#44; and a positive histological diagnosis was obtained in 92&#44;53&#37;&#46; In 44 out of our 174 cases the stereotactic system was used not only to obtain a cytological diagnosis but also to deflate a cyst cavity &#40;tumoral or abscess&#41; or to insert or remove a radioactive isotope&#46; The patient&#39;s postbiopsy course was excellent in 32 &#40;18&#44;39&#37;&#41; and unchanged in 136 &#40;78&#44;16&#37;&#41;&#46; One patient died&#44; which corresponds to a mortality rate of 0&#44;57&#37;&#46; The transitory morbidity was 2&#44;87&#37; &#40;5 cases&#41;&#46; No permanent morbidity was noted&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To determine the efficiency of our stereotactic methodology we evaluated the relationship between our presumptive diagnosis from the cl&#237;nical and neuroradiological studies and the final histological results&#46; The presumptive diagnosis was confirmed in 58&#44;39&#37;&#44; in 12&#44;75&#37; the differences were in the degree of tumor anaplasia and in 28&#44;86&#37; our diagnosis was incorrect&#46; Angiography was considered very useful in localizing the target and in avoiding intraoperative haemorrhage&#46; Impedance monitoring gave us important information regarding the trajectory and depth of the target according to the tissue resistance encountered&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">From our experience&#44; we think that stereotactic techniques represent an alternative to blind management of an important part of intracranial pathology&#44; and a rational way to obtain a more accurate diagnosis&#46;</p>"
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