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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Exponemos nuestra experiencia en el tratamiento de los neurinomas del ac&#250;stico con radiocirug&#237;a&#44; mediante un aparato de telecobaltoterapia &#40;Theraton 80&#41;&#44; acoplado a un sistema de esterot&#225;xia&#44; en cinco pacientes ancianos&#44; cuya edad promedio fue de 70 a&#241;os&#46; Todos ellos presentaban patolog&#237;as graves asociadas que imped&#237;an el tratamiento quir&#250;rgico&#46; El di&#225;metro promedio del tumor era de 21<span class="elsevierStyleHsp" style=""></span>mm&#46; Se administr&#243; radioterapia &#40;Radiocirug&#237;a&#41;&#44; con una dosis promedio de 2&#46;770 cGy &#40;rango 2500 a 3750 cGy&#41; en una sola sesi&#243;n&#44; mediante un promedio de 17&#44;8 campos isoc&#233;ntricos con un colimador de 20<span class="elsevierStyleHsp" style=""></span>mm&#46; de di&#225;metro&#46; La repartici&#243;n de la isodosis se hizo de la siguiente manera&#58; en los casos 2 y 4 el 90&#37; de la isodosis alcanz&#243; la periferia del tumor&#44; en el caso 5 el 80&#37;&#44; en el caso 3 el 40&#37;&#44; mientras que en el caso 1&#44; s&#243;lo el 20&#37; de la isodosis alcanz&#243; la periferia del tumor&#46; La radiaci&#243;n fue bien tolerada por todos los pacientes&#46; La TAC de control puso de manifiesto la disminuci&#243;n del tama&#241;o de la lesi&#243;n en 3 pacientes y la aparici&#243;n de una zona hipodensa central en 2&#46; Un paciente desarrollo hidrocefalia y radionecrosis de cerebelo que precis&#243; derivaci&#243;n del LCR y tratamiento con corticoides&#46; Dos pacientes tuvieron una buena recuperaci&#243;n&#44; otro ten&#237;a una moderada incapacidad y 2 se han estabilizado&#44; pero son incapaces de valerse por si mismos&#44; dependencia que ya la ten&#237;an&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Consideramos que la radiocirug&#237;a estereot&#225;xica empleando cobalto 60 &#40;Co 60&#41;&#44; es una alternativa a la extirpaci&#243;n quir&#250;rgica o a la simple observaci&#243;n cl&#237;nica y tomodensitom&#233;trica&#44; en pacientes ancianos o con patolog&#237;as graves asociadas&#46;</p>"
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        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We present our initial experience with 5 patients treated for acoustic neurinoma by stereotactic radiosurgery using a Theratron 80 fitted to a stereotactic system&#44; during the last four years&#46; The average age of the patients was 70 years and alI of them suffered from associated serious pathology which prevented conventional surgery&#46; The tumours averaged 21<span class="elsevierStyleHsp" style=""></span>mm in diameter and the radiation doses delivered ranged from 2&#46;500 to 3&#46;750 cGy &#40;mean 2&#46;770 cGy&#41; and were administered in a single session&#46; The fields was 17&#44;8 and the diameter of the collimators averaged 20<span class="elsevierStyleHsp" style=""></span>m&#46; In cases 2 and 4 the 90&#37; isodose overtook the periphery of the tumour&#44; the 80&#37; isodose in case 5&#44; the 40&#37; isodose in case 3&#44; and in case 1 onIy the 20&#37; isodose overtook the perifery of the tumour&#46; Radiosurgery was well tolerated by all the patients&#46; The control CT scan showed centralloss of contrast enhancement in 2 patients&#44; and shrinkage of the tumor in 3&#46; One patient developed hydrocephalus and radionecrosis who required CSF shunting and corticoteroids&#46; The final outcome was as follows&#58; two patients presented a good evolution&#44; one patient developed a moderate disability and two more patients are unchanged but dependent&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Stereotactic radiosurgery is a good alternative to conventional surgery on nonsurgical management for patient with acoustic neurinoma who are elderly or medically ill&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Rubio Garc&#237;a&#44; E&#46;&#59; Casta&#241;o Duque&#44; C&#46;H&#46;&#59; Vilalta Cast&#225;n&#44; J&#46;&#59; Quesada Marin&#44; P&#46;&#59; Garc&#237;a Arumi&#44; A&#46;&#59; Guix Melcior&#44; B&#46;&#59; Bosch Blancafort&#44; J&#46;&#58; Neurinomas del ac&#250;stico tratados con radiocirug&#237;a estereot&#225;xica&#46; A prop&#243;sito de cinco casos&#46; Neurocirug&#237;a 1992&#59; 3&#58; 141&#8211;148&#46;</p>"
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Neurinomas del acústico tratados con radiocirugía estereotáxica. A propósito de cinco casos
E. Rubio García, C.H. Castaño Duque, J. Vilalta Castán, J. Bosch Blancafort
Servicio de Neurocirugía, Hospital Vall d’Hebrón. Barcelona
P. Quesada Marin*, A. García Arumi*, B. Guix Melcior**
* Servicio de ORL, Hospital Vall d’Hebrón. Barcelona
** Servicio de Radioterapia, Clínica Dexeus. Barcelona
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            1 => "Radiotherapy"
            2 => "Stereotactic Radiosurgery"
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        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Exponemos nuestra experiencia en el tratamiento de los neurinomas del ac&#250;stico con radiocirug&#237;a&#44; mediante un aparato de telecobaltoterapia &#40;Theraton 80&#41;&#44; acoplado a un sistema de esterot&#225;xia&#44; en cinco pacientes ancianos&#44; cuya edad promedio fue de 70 a&#241;os&#46; Todos ellos presentaban patolog&#237;as graves asociadas que imped&#237;an el tratamiento quir&#250;rgico&#46; El di&#225;metro promedio del tumor era de 21<span class="elsevierStyleHsp" style=""></span>mm&#46; Se administr&#243; radioterapia &#40;Radiocirug&#237;a&#41;&#44; con una dosis promedio de 2&#46;770 cGy &#40;rango 2500 a 3750 cGy&#41; en una sola sesi&#243;n&#44; mediante un promedio de 17&#44;8 campos isoc&#233;ntricos con un colimador de 20<span class="elsevierStyleHsp" style=""></span>mm&#46; de di&#225;metro&#46; La repartici&#243;n de la isodosis se hizo de la siguiente manera&#58; en los casos 2 y 4 el 90&#37; de la isodosis alcanz&#243; la periferia del tumor&#44; en el caso 5 el 80&#37;&#44; en el caso 3 el 40&#37;&#44; mientras que en el caso 1&#44; s&#243;lo el 20&#37; de la isodosis alcanz&#243; la periferia del tumor&#46; La radiaci&#243;n fue bien tolerada por todos los pacientes&#46; La TAC de control puso de manifiesto la disminuci&#243;n del tama&#241;o de la lesi&#243;n en 3 pacientes y la aparici&#243;n de una zona hipodensa central en 2&#46; Un paciente desarrollo hidrocefalia y radionecrosis de cerebelo que precis&#243; derivaci&#243;n del LCR y tratamiento con corticoides&#46; Dos pacientes tuvieron una buena recuperaci&#243;n&#44; otro ten&#237;a una moderada incapacidad y 2 se han estabilizado&#44; pero son incapaces de valerse por si mismos&#44; dependencia que ya la ten&#237;an&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Consideramos que la radiocirug&#237;a estereot&#225;xica empleando cobalto 60 &#40;Co 60&#41;&#44; es una alternativa a la extirpaci&#243;n quir&#250;rgica o a la simple observaci&#243;n cl&#237;nica y tomodensitom&#233;trica&#44; en pacientes ancianos o con patolog&#237;as graves asociadas&#46;</p>"
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      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We present our initial experience with 5 patients treated for acoustic neurinoma by stereotactic radiosurgery using a Theratron 80 fitted to a stereotactic system&#44; during the last four years&#46; The average age of the patients was 70 years and alI of them suffered from associated serious pathology which prevented conventional surgery&#46; The tumours averaged 21<span class="elsevierStyleHsp" style=""></span>mm in diameter and the radiation doses delivered ranged from 2&#46;500 to 3&#46;750 cGy &#40;mean 2&#46;770 cGy&#41; and were administered in a single session&#46; The fields was 17&#44;8 and the diameter of the collimators averaged 20<span class="elsevierStyleHsp" style=""></span>m&#46; In cases 2 and 4 the 90&#37; isodose overtook the periphery of the tumour&#44; the 80&#37; isodose in case 5&#44; the 40&#37; isodose in case 3&#44; and in case 1 onIy the 20&#37; isodose overtook the perifery of the tumour&#46; Radiosurgery was well tolerated by all the patients&#46; The control CT scan showed centralloss of contrast enhancement in 2 patients&#44; and shrinkage of the tumor in 3&#46; One patient developed hydrocephalus and radionecrosis who required CSF shunting and corticoteroids&#46; The final outcome was as follows&#58; two patients presented a good evolution&#44; one patient developed a moderate disability and two more patients are unchanged but dependent&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Stereotactic radiosurgery is a good alternative to conventional surgery on nonsurgical management for patient with acoustic neurinoma who are elderly or medically ill&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Rubio Garc&#237;a&#44; E&#46;&#59; Casta&#241;o Duque&#44; C&#46;H&#46;&#59; Vilalta Cast&#225;n&#44; J&#46;&#59; Quesada Marin&#44; P&#46;&#59; Garc&#237;a Arumi&#44; A&#46;&#59; Guix Melcior&#44; B&#46;&#59; Bosch Blancafort&#44; J&#46;&#58; Neurinomas del ac&#250;stico tratados con radiocirug&#237;a estereot&#225;xica&#46; A prop&#243;sito de cinco casos&#46; Neurocirug&#237;a 1992&#59; 3&#58; 141&#8211;148&#46;</p>"
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                          "etal" => false
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                            0 => "P&#46; Bentivoglio"
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                          "etal" => false
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                            2 => "J&#46;D&#46; Acker"
                            3 => "L&#46;G&#46; Gardner"
                            4 => "F&#46; Eggers"
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                            0 => "N&#46;L&#46; Cohen"
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                          "etal" => false
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ISSN: 11301473
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