Tumor neuroepitelial disembrioplásico: una causa de epilepsia curable quirúrgicamente
J. Vaquero, M. Zurita, S. Coca, S. Oya, F. de Prado
Servicio de Neurocirugía, Hospital Universitario Clínica Puerta de Hierro, Universidad Autónoma
Departamento de Biología Celular, Facultad de Medicina de la Universidad Complutense y Servicio de Anatomía Patológica, Hospital Universitario del Ejército del Aire. Madrid
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"apellidos" => "Castillo Escandón" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147396707522?idApp=UINPBA00004B" "url" => "/11301473/0000000700000001/v1_201305151450/S1130147396707522/v1_201305151450/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Tumor neuroepitelial disembrioplásico: una causa de epilepsia curable quirúrgicamente" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "19" "paginaFinal" => "26" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J. Vaquero, M. Zurita, S. Coca, S. Oya, F. de Prado" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Vaquero" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Zurita" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Coca" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "Oya" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "de Prado" ] ] "afiliaciones" => array:2 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía, Hospital Universitario Clínica Puerta de Hierro, Universidad Autónoma" ] 1 => array:1 [ "entidad" => "Departamento de Biología Celular, Facultad de Medicina de la Universidad Complutense y Servicio de Anatomía Patológica, Hospital Universitario del Ejército del Aire. Madrid" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec162928" "palabras" => array:4 [ 0 => "Tumor neuroepitelial disembrioplásico" 1 => "Neurocitoma" 2 => "Epilepsia" 3 => "Tumor cerebral" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec162927" "palabras" => array:4 [ 0 => "Dysembryoplastic neuroepithelial tumor" 1 => "Neurocytoma" 2 => "Epilepsy" 3 => "Brain tumor" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Los llamados «Tumores neuroepiteliales disembrioplásicos » (TND) fueron individualizados en 1988 por Daumas-Duport y cols. Clínicamente se manifiestan por una historia de larga evolución consistente en crisis epilépticas rebeldes al tratamiento médico. Anatomopatológicamente sus células predominantes son de pequeño tamaño, con aspecto similar, desde el punto de vista de la microscopía óptica, al de las células de oligodendroglía, y se asocian a alteraciones neuronales, con desorganización de la corteza cerebral. En la presente publicación se aportan 2 nuevos casos de TND y se revisan los aspectos anatomoclínicos de esta entidad. Nuestros hallazgos confirman observaciones previas en el sentido de que estas neoplasias son biológicamente benignas y constituyen básicamente lesiones epileptogénicas susceptibles de ser tratadas quirúrgicamente con magníficos resultados. Por otra parte, el estudio anatomopatológico realizado en nuestros casos demuestra la naturaleza neuronal de estos tumores, lo que unido a observaciones recogidas en la literatura, nos lleva a sugerir que los llamados «tumores neuroepiteliales disembrioplásicos» deberían ser reclasificados como «neurocitomas disembrioplásicos».</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The so-called dysembryoplastic neuroepithelial tumors (DNT) were described by Daumas-Duport el al. in 1988, as a clinico-pathological entity. These tumors cause chronic medically intractable seizures, and the main constituent cells show features of oligodendrocytes when they were studied by optical microscopy. The association with neuronal atypias and cortical dysplasia is a frequent finding. In the present report we describe two cases of DNT and the clinical and pathological features of this entity are revised. Our present results agree with previous reports showing the benignity of DNT and their character of epileptogenic lesioils surgically curable. On the other hand, our pathological study suggests the neuronal nature of DNT and their reclassification as «dysembryoplastic neurocytomas » is proposed.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Vaquero, J.; Zurita, M.; Coca, S.; Oya, S.; De Prado, F.: Tumor neuroepitelial disembrioplásico: Una causa de epilepsía curable quirúrgicamente. Neurocirugía 1996; 7: 19–26.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2023 Marzo | 5 | 2 | 7 |
| 2023 Enero | 0 | 2 | 2 |
| 2018 Marzo | 2 | 1 | 3 |
| 2018 Febrero | 62 | 16 | 78 |
| 2018 Enero | 45 | 15 | 60 |
| 2017 Diciembre | 53 | 17 | 70 |
| 2017 Noviembre | 132 | 80 | 212 |
| 2017 Octubre | 141 | 47 | 188 |
| 2017 Septiembre | 65 | 40 | 105 |
| 2017 Agosto | 93 | 61 | 154 |
| 2017 Julio | 88 | 62 | 150 |
| 2017 Junio | 95 | 62 | 157 |
| 2017 Mayo | 120 | 95 | 215 |
| 2017 Abril | 69 | 50 | 119 |
| 2017 Marzo | 42 | 75 | 117 |
| 2017 Febrero | 59 | 91 | 150 |
| 2017 Enero | 28 | 46 | 74 |
| 2016 Diciembre | 43 | 39 | 82 |
| 2016 Noviembre | 30 | 67 | 97 |
| 2016 Octubre | 52 | 73 | 125 |
| 2016 Septiembre | 98 | 167 | 265 |
| 2016 Agosto | 121 | 156 | 277 |
| 2016 Julio | 61 | 89 | 150 |
| 2015 Diciembre | 2 | 0 | 2 |
| 2015 Octubre | 1 | 0 | 1 |
| 2015 Agosto | 2 | 0 | 2 |
| 2015 Julio | 0 | 5 | 5 |
| 2015 Junio | 11 | 21 | 32 |
| 2015 Mayo | 21 | 51 | 72 |
| 2015 Abril | 19 | 31 | 50 |
| 2015 Marzo | 18 | 47 | 65 |
| 2015 Febrero | 12 | 62 | 74 |
| 2015 Enero | 13 | 49 | 62 |
| 2014 Diciembre | 17 | 36 | 53 |
| 2014 Noviembre | 12 | 60 | 72 |
| 2014 Octubre | 17 | 62 | 79 |
| 2014 Septiembre | 22 | 32 | 54 |
| 2014 Agosto | 21 | 57 | 78 |
| 2014 Julio | 23 | 44 | 67 |
| 2014 Junio | 12 | 44 | 56 |
| 2014 Mayo | 19 | 49 | 68 |
| 2014 Abril | 19 | 46 | 65 |
| 2014 Marzo | 17 | 35 | 52 |
| 2014 Febrero | 19 | 50 | 69 |
| 2014 Enero | 16 | 34 | 50 |
| 2013 Diciembre | 15 | 19 | 34 |
| 2013 Noviembre | 24 | 34 | 58 |
| 2013 Octubre | 17 | 47 | 64 |
| 2013 Septiembre | 33 | 45 | 78 |
| 2013 Agosto | 16 | 59 | 75 |
| 2013 Julio | 12 | 53 | 65 |
| 2013 Junio | 17 | 67 | 84 |
| 2013 Mayo | 16 | 39 | 55 |
| 2013 Abril | 17 | 56 | 73 |
| 2013 Marzo | 14 | 47 | 61 |
| 2013 Febrero | 20 | 26 | 46 |
| 2013 Enero | 13 | 19 | 32 |
| 2012 Diciembre | 8 | 21 | 29 |
| 2012 Noviembre | 1 | 19 | 20 |
| 2012 Octubre | 0 | 5 | 5 |
| 2012 Septiembre | 0 | 2 | 2 |
| 2012 Enero | 8 | 0 | 8 |
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