Compartir
array:23 [ "pii" => "S1130147393708623" "issn" => "11301473" "doi" => "10.1016/S1130-1473(93)70862-3" "estado" => "S300" "fechaPublicacion" => "1993-01-01" "aid" => "70862" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1993" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1993;4:125-31" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4452 "formatos" => array:3 [ "EPUB" => 32 "HTML" => 1340 "PDF" => 3080 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147393708635" "issn" => "11301473" "doi" => "10.1016/S1130-1473(93)70863-5" "estado" => "S300" "fechaPublicacion" => "1993-01-01" "aid" => "70863" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1993;4:132-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3137 "formatos" => array:3 [ "EPUB" => 30 "HTML" => 875 "PDF" => 2232 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Metástasis cerebrales de larga evolución. Factores pronósticos favorables. A propósito de dos casos" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "132" "paginaFinal" => "134" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L.J.M. Soto, E. Areitio, J. Salazar, J.B. Uribarri, M.G. Fantini, J. de la Herran" "autores" => array:6 [ 0 => array:2 [ "nombre" => "L.J.M." "apellidos" => "Soto" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Areitio" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Salazar" ] 3 => array:2 [ "nombre" => "J.B." "apellidos" => "Uribarri" ] 4 => array:2 [ "nombre" => "M.G." "apellidos" => "Fantini" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "de la Herran" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147393708635?idApp=UINPBA00004B" "url" => "/11301473/0000000400000002/v1_201305151425/S1130147393708635/v1_201305151425/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147393708611" "issn" => "11301473" "doi" => "10.1016/S1130-1473(93)70861-1" "estado" => "S300" "fechaPublicacion" => "1993-01-01" "aid" => "70861" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1993;4:120-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3847 "formatos" => array:3 [ "EPUB" => 33 "HTML" => 1425 "PDF" => 2389 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Hematomas epidurales de fosa posterior" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "120" "paginaFinal" => "124" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Gelabert González, A. Prieto González, R. Martínez Rumbo, A. Bollar Zabala, A. García Allut" "autores" => array:5 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Gelabert González" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Prieto González" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Martínez Rumbo" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Bollar Zabala" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "García Allut" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147393708611?idApp=UINPBA00004B" "url" => "/11301473/0000000400000002/v1_201305151425/S1130147393708611/v1_201305151425/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Factores pronósticos en la evolución de los ependimomas intracraneales" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "125" "paginaFinal" => "131" ] ] "autores" => array:2 [ 0 => array:3 [ "autoresLista" => "J. Piquer, J. Cabanes, P. Riesgo, C. Botella, J. Navarro, M. Orozco, J. Alvarez Garijo" "autores" => array:7 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Piquer" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Cabanes" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Riesgo" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Botella" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Navarro" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Orozco" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Alvarez Garijo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Hospital Universitario La Fe. Valencia" ] ] ] 1 => array:3 [ "autoresLista" => "M. Hemández, J.A. Ramos" "autores" => array:2 [ 0 => array:3 [ "nombre" => "M." "apellidos" => "Hemández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "J.A." "apellidos" => "Ramos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Neurocirugía; Servicio de Anatomía Patológica" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec162450" "palabras" => array:4 [ 0 => "Ependimoma" 1 => "pronóstico" 2 => "supervivencia postoperatoria" 3 => "neoplasia cerebral" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec162451" "palabras" => array:4 [ 0 => "Ependymoma" 1 => "prognosis" 2 => "postoperative survival" 3 => "brain neoplasm" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se analizan los factores pronósticos y supervivencia de 38 pacientes afectados de ependimomas intracraneales, que fueron intervenidos quirúrgicamente en el Hospital La Fe de Valencia durante el período 1969–1990. La edad media fue de 12 años (rango, 1–59 años). Se practicó resección total de la lesión en 17 pacientes, subtotal en 20 y parcial en uno. La histología tumoral fue revisada en cada caso y se agrupó en ependimomas de bajo (58%) y alto grado de malignidad (42%). En 16 pacientes se administró radioterapia complementaria (dosis media 4900 cGy). El tiempo medio de seguimiento se aproximó a los 49 meses, siendo la probabilidad de supervivencia a los 5 años del 58% tras excluir la mortalidad operatoria. Los factores que se asociaron con una supervivencia más favorable fueron: extirpación radical, histología de bajo grado, radioterapia complementaria y ausencia de signos de invasión de tronco o pares craneales. Por el contrario, la supervivencia fue menor en aquellos casos con signos de invasión de tronco o pares craneales, extirpación subtotal o parcial, histología de alto grado y desestimación de radioterapia complementaria. El grado histológico de la neoplasia fue la única variable con valor pronóstico estadísticamente significativo (p<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>0,05).</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The prognostic factors and survival data were analyzed for 38 patients with intracranial ependymoma treated surgically at the Hospital La Fe in Valencia during the years 1969 to 1990. The median age was 12 years (range, 1–59 yr). Gross total resection was performed in 17 patients, subtotal in 20 and partial in only 1 case. Tumor histology was reviewed individually and grouped into low grade (58%) and high grade (42%). Sixteen patients underwent radiotherapy (median dose 4900 cGy). With a median follow-up of 49 monts, the actuarial survival rates at 5 years were 58% after the exclusion of perioperative mortality. Factors associated with an improved 5-year survival rate were: total tumor removal, low grade histology, radiation therapy and absent brain-stem o cranial nerve signs in infratentorial cases. The 5-year survival rate was lower when associated with presence of physical signs of parenchymal invasion or lower cranial nerve involvement in infratentorial tumors, subtotal tumor removal, high grade histology and no radiotherapy treatment. The tumor's histological grade was the onIy prognostic variable with significant difference (p<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>0,05).</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Piquer, J.; Cabanes, J.; Hemández, M.; Riesgo, P.; Ramos, J.A.; Botella, C.; Navarro, J.; Orozco, M.; Alvarez Garijo, J.: Factores pronósticos en la evolución de los ependimomas intracraneales. Neurocirugía 1993; 4: 125–131.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:43 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial tumors: Response and resistance to therapeutic endeavors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.J.G. Bloom" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int J Radiot Oncol Biol Phys" "fecha" => "1992" "volumen" => "8" "paginaInicial" => "1083" "paginaFinal" => "1113" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Observations on growth rates of human tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "V.P. Collins" 1 => "R.K. Loeffler" 2 => "H. Tivey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Roentgenol" "fecha" => "1956" "volumen" => "76" "paginaInicial" => "988" "paginaFinal" => "1000" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymoma. Results of radiotherapy at the University of Kentucky" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H.W. Chin" 1 => "Y. Maruyama" 2 => "W. Markesbery" 3 => "B.A. Young" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1982" "volumen" => "42" "paginaInicial" => "2276" "paginaFinal" => "2280" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postoperative irradiation of brain ependymomas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Di Marco" 1 => "F. Campostrini" 2 => "R. Pradella" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Analysis of 33 cases. Acta Oncol" "fecha" => "1988" "volumen" => "27" "paginaInicial" => "261" "paginaFinal" => "267" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.L. Dohrmann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Neurosurgery" "paginaInicial" => "767" "paginaFinal" => "771" "serieFecha" => "1985" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas and ependymoblastomas in children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.L. Dohrmann" 1 => "J.R. Farwell" 2 => "J.T. Flannery" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1976.45.3.0273" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1976" "volumen" => "45" "paginaInicial" => "273" "paginaFinal" => "283" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/948014" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of brain tumors in babies and very young children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.K. Duffner" 1 => "M.E. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Neurosci" "fecha" => "1985" "volumen" => "12" "paginaInicial" => "304" "paginaFinal" => "310" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3916645" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Prognostic significance of postoperative residual tumor in ependymoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:4 [ 0 => "F.J. Epstein" 1 => "E.A. Healey" 2 => "P.D. Barnes" 3 => "W.J. Kupsky" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery" "fecha" => "1991" "volumen" => "28" "paginaInicial" => "666" "paginaFinal" => "672" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1876244" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymomas: Prognostic aspects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.I. Ernestus" 1 => "O. Wilcke" 2 => "R. Schroder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurg Rev" "fecha" => "1989" "volumen" => "12" "paginaInicial" => "157" "paginaFinal" => "163" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2779795" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Supratentorial ependymomas in Chilhood. Clinicopathological Findings and Prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.I. Ernestus" 1 => "O. Wilcke" 2 => "R. Schroder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Neurochir" "fecha" => "1991" "volumen" => "111" "paginaInicial" => "96" "paginaFinal" => "102" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1950695" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas. Clinical and pathological aspects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Fokes" 1 => "K.M. Earle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1969.30.5.0585" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1969" "volumen" => "30" "paginaInicial" => "585" "paginaFinal" => "594" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5305351" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas: Results of radiation treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.G. Garrett" 1 => "W.J.K. Simpson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int Radiot Oncol Biol Phys" "fecha" => "1983" "volumen" => "9" "paginaInicial" => "1121" "paginaFinal" => "1124" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Prognostic significance of postoperative residual tumor in ependymoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "E.A. Healey" 1 => "P.D. Barnes" 2 => "W.J. Kupsky" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery" "fecha" => "1991" "volumen" => "28" "paginaInicial" => "666" "paginaFinal" => "672" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1876244" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas: a clinical and pathological study. Part II - survival features" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "E.B. Ilgren" 1 => "C.A. Stiller" 2 => "J.T. Hughes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Neuropathol" "fecha" => "1984" "volumen" => "3" "paginaInicial" => "113" "paginaFinal" => "121" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6205805" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Non paramétric estimation for incomplete observations" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.L. Kaplan" 1 => "P. Meier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Am. Stat Assoc" "fecha" => "1958" "volumen" => "53" "paginaInicial" => "457" "paginaFinal" => "481" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Y.H. Kim" 1 => "J.V. Fayons" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/124.3.805" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1977" "volumen" => "124" "paginaInicial" => "805" "paginaFinal" => "808" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/887779" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymomas: A study of survival in 65 cases treated by surgery and irradiation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "I.I. Kricheff" 1 => "M. Becker" 2 => "S.A. Schmneck" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Roentgenol" "fecha" => "1964" "volumen" => "91" "paginaInicial" => "167" "paginaFinal" => "175" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymomas: factors influencing prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I.L. Kricheff" 1 => "M. Becker" 2 => "S.A. Schneck" 3 => "J.M. Taveras" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1964.21.1.0007" "Revista" => array:6 [ "tituloSerie" => "J Neurosurg" "fecha" => "1964" "volumen" => "21" "paginaInicial" => "7" "paginaFinal" => "14" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14110365" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiation therapy for neoplasms of the brain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.A. Leibel" 1 => "G.E. Heline" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1987.66.1.0001" "Revista" => array:6 [ "tituloSerie" => "J Neurosurg" "fecha" => "1987" "volumen" => "66" "paginaInicial" => "1" "paginaFinal" => "22" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3023563" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Les épendymomes intracraniens: Experience de 86 cas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.P. Lejeune" 1 => "P. Dhellemmes" 2 => "T. Dupard" 3 => "G. Combelles" 4 => "J.M. Delandsheer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurochirurgie" "fecha" => "1987" "volumen" => "33" "paginaInicial" => "118" "paginaFinal" => "123" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3600940" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas of childhood I. Historical survey and clinicopathological correlation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.M. Liu" 1 => "J. BOOGS" 2 => "J. Kidd" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Childs Brain" "fecha" => "1976" "volumen" => "2" "paginaInicial" => "92" "paginaFinal" => "110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/971635" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Posterior fossa ependymomas. Report of 30 cases and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.K. Lyons" 1 => "P.J. Kelly" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1991" "volumen" => "28" "paginaInicial" => "659" "paginaFinal" => "665" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comparative study of ependymomas by site of origino" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.E. Marks" 1 => "S.J. Adler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Radiat Oncol Biol Phys" "fecha" => "1982" "volumen" => "8" "paginaInicial" => "37" "paginaFinal" => "43" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7061255" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas: A follow-up sutdy of 101 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.J. Mork" 1 => "A.C. Loken" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1977" "volumen" => "40" "paginaInicial" => "907" "paginaFinal" => "915" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/890671" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymoblastoma. A praisal of arare embryonal tumor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.J. Mork" 1 => "L.J. Rubinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1985" "volumen" => "55" "paginaInicial" => "1536" "paginaFinal" => "1542" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3978547" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Les ependymomes intracraniens: Etude de 81 cas et comparaison avec la litérature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I.J. Namer" 1 => "M.N. Pamir" 2 => "K. Benli" 3 => "A. Erbengi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurochirurgie" "fecha" => "1984" "volumen" => "30" "paginaInicial" => "153" "paginaFinal" => "158" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6462320" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Infratentorial ependymoma in Chilhood Prognosis factors and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.B. Nazar" 1 => "H.J. Hoffman" 2 => "R. Schroder" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1990.72.3.0408" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1990" "volumen" => "72" "paginaInicial" => "408" "paginaFinal" => "417" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2303876" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial ependymomas in childhood: Survival and functional results of 47 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Pierre-Kahn" 1 => "J.F. Hirsch" 2 => "F.X. Roux" 3 => "D. Reiner" 4 => "C. Sainte-Rose" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Childs Brain" "fecha" => "1983" "volumen" => "10" "paginaInicial" => "145" "paginaFinal" => "156" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6872622" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas: a clinicopathologic study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.E. Rawlings" 1 => "F. Giangaspero" 2 => "P.C. Burger" 3 => "D.E. Bullar" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surg Neurol" "fecha" => "1988" "volumen" => "29" "paginaInicial" => "271" "paginaFinal" => "281" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3353839" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The treatment of ependymomas of the brain or spinal canal by radiotherapy: A report of 79 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Read" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Radiol" "fecha" => "1984" "volumen" => "35" "paginaInicial" => "163" "paginaFinal" => "166" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6697658" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relationship of morphology of ependymoma in children to prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.B. Rorke" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Prog Exp Tumor Res" "fecha" => "1978" "volumen" => "30" "paginaInicial" => "170" "paginaFinal" => "174" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3628803" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lack of histopathological correlation of malignant ependymomas with postoperative survival" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.W. Ross" 1 => "L.J. Rubinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1989.70.1.0031" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1989" "volumen" => "70" "paginaInicial" => "31" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2909684" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical correlations of malignant ependymomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.J. Rubinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Primary Brain Tumors: A Review of Histologic Classification" "paginaInicial" => "191" "paginaFinal" => "194" "serieFecha" => "1989" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The definition of the ependymoblastoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.J. Rubinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Pathol" "fecha" => "1970" "volumen" => "90" "paginaInicial" => "35" "paginaFinal" => "45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5426275" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improved survival in cases of intracranial ependymoma after radiation therapy. Late report and recommendations" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.M. Salazar" 1 => "H. Castro-Vita" 2 => "P. Vanhoutte" 3 => "P. Rubin" 4 => "C. Aygun" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/jns.1983.59.4.0652" "Revista" => array:6 [ "tituloSerie" => "J. Neurosurg" "fecha" => "1983" "volumen" => "59" "paginaInicial" => "652" "paginaFinal" => "659" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6886786" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymoma: Internal correlations among pathologica signs" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "D. Schiffer" 1 => "A. Chio" 2 => "H. Cranioto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Neurosurgery" "fecha" => "1991" "volumen" => "29" "paginaInicial" => "206" "paginaFinal" => "210" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1886658" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vascular response to irradiation in malignant gliomas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "D. Schiffer" 1 => "A. Chio" 2 => "M.T. Giordana" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Neuro-oncol" "fecha" => "1990" "volumen" => "8" "paginaInicial" => "73" "paginaFinal" => "84" ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postoperative radiotherapy of intracranial ependymoma in pediatric and adult patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.G. Shaw" 1 => "R.G. Evans" 2 => "B.W. Scheithauer" 3 => "D.M. Ilstrup" 4 => "J.D. Earle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int J Radiat Dncol Biol Phys" "fecha" => "1987" "volumen" => "13" "paginaInicial" => "1457" "paginaFinal" => "1462" ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.L. Silverman" 1 => "P.R.M. Thomas" 2 => "W. Cox" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Management of Childhood Brain Tumors" "paginaInicial" => "369" "paginaFinal" => "382" "serieFecha" => "1990" ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Benign ependymomas of the posterior fossa in childhood" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Tomita" 1 => "D.G. Mclone" 2 => "L. Das" 3 => "W.N. Brand" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Neurosci" "fecha" => "1988" "volumen" => "14" "paginaInicial" => "277" "paginaFinal" => "285" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3270047" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiation therapy for brain tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.M. Wara" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1985" "volumen" => "55" "paginaInicial" => "2291" "paginaFinal" => "2295" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2983878" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ependymomas: Factors and clinical and diagnostic stagin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.R. West" 1 => "D.A. Bruce" 2 => "P.K. Duffner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Cancer" "fecha" => "1985" "volumen" => "56" "numero" => "Suppl" "paginaInicial" => "1812" "paginaFinal" => "1816" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4027918" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Brain Tumors: Their Biology and Pathology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K.J. Zulch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1986" "editorial" => "Springer-Verlag" "editorialLocalizacion" => "New York" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/11301473/0000000400000002/v1_201305151425/S1130147393708623/v1_201305151425/es/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/11301473/0000000400000002/v1_201305151425/S1130147393708623/v1_201305151425/es/main.pdf?idApp=UINPBA00004B&text.app=https://revistaneurocirugia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147393708623?idApp=UINPBA00004B" ]
