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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Existen estudios experimentales sobre el mejoramiento del vasoespasmo que sigue a la hemorragia subaracnoidea por la Actinomicina D&#44; pero no existe ning&#250;n estudio acerca de su efecto en la isquemia cerebral&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hemos realizado el presente estudio experimental en 18 ratas&#59; produci&#233;ndoles isquemia cerebral parcial &#40;mediante ligadura permanente de la arteria car&#243;tida com&#250;n derecha&#44; y clipaje transitorio de la car&#243;tida com&#250;n izquierda&#41;&#44; que fueron tratadas con Actinomicina D &#40;v&#237;a intraperitoneal&#41; por 5 d&#237;as&#46; Se administr&#243; dicha sustancia a las 6 y 12 horas postisquemia&#44; en los grupos A &#40;6 ratas&#41; y B &#40;6 ratas&#41; respectivamente&#46; El grupo C &#40;control&#41; constitu&#237;do tambi&#233;n por 6 ratas&#44; no recibi&#243; tratamiento alguno&#46; El an&#225;lisis estad&#237;stico antes y despu&#233;s del tratamiento se realiz&#243; observando las modificaciones del flujo sangu&#237;neo cerebral utilizando HMPAO marcado con Tc-99m &#40;marcador radioactivo&#41;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se encontr&#243; ausencia de modificaci&#243;n del flujo sangu&#237;neo cerebral&#44; y por lo tanto ausencia de mejor&#237;a de la isquemia cerebral&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se concluye que la Actinomicina D no modifica el flujo sangu&#237;neo ni mejora la isquemia cerebral experimental en ratas&#46;</p>"
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        "resumen" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Though there are some studies reporting a favourable effect of Actinomycin D posthemorrhagic cerebral vasospasm&#44; the effect of this drug on brain ischemia has not been analyzed&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We have performed an experimental study in 18 rats&#46; Ischemia was produced by permanent and transitory ligature of the right and left common carotid artery respectively&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The animals were divided into three groups&#46; Actinomycin was injected intraperitoneally 6 and 12 hours after ischemia in groups A and B&#46; Animals in group C did not receive any treatment&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Cerebral blood flow &#40;CBF&#41; was measured using HMPAO labeled with Tc 99m&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">There was no modification of CBF&#46; The conclusion is that Actinomycin D does not improve cerebral ischemia in this experimental model&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Posadas Narro&#44; G&#46;&#59; Haro del Moral&#44; J&#46; de&#59; Vaquero Crespo&#44; J&#46;&#59; San Juan Robles&#44; C&#46;&#59; Bravo Zabalgoitia&#44; G&#46; y Ortiz Berrocal&#44; J&#46;&#58; Influencia de la actinomicina D sobre el flujo sangu&#237;neo cerebral en un modelo de isquemia experimental&#46; Neurocirug&#237;a 1994&#59; 5&#58; 10&#8211;15&#46;</p>"
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Horario de 9 a 18h. excepto los meses de julio y agosto que será de 9 a 15h.
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¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?