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array:22 [ "pii" => "S1130147390709463" "issn" => "11301473" "doi" => "10.1016/S1130-1473(90)70946-3" "estado" => "S300" "fechaPublicacion" => "1990-01-01" "aid" => "70946" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1990" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1990;1:28-34" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2048 "formatos" => array:3 [ "EPUB" => 10 "HTML" => 876 "PDF" => 1162 ] ] "itemAnterior" => array:18 [ "pii" => "S1130147390709451" "issn" => "11301473" "doi" => "10.1016/S1130-1473(90)70945-1" "estado" => "S300" "fechaPublicacion" => "1990-01-01" "aid" => "70945" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1990;1:25-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2245 "formatos" => array:3 [ "EPUB" => 11 "HTML" => 876 "PDF" => 1358 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Hematomas intracerebelosos traumáticos" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "25" "paginaFinal" => "27" ] ] "contieneResumen" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Gelabert González, A. Bollar Zabala, M.J. Paseiro García, A. García Allut, R. Martínez Rumbo, F. Reyes Oliveros" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Gelabert González" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Bollar Zabala" ] 2 => array:2 [ "nombre" => "M.J." "apellidos" => "Paseiro García" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "García Allut" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Martínez Rumbo" ] 5 => array:2 [ "nombre" => "F." "apellidos" => "Reyes Oliveros" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147390709451?idApp=UINPBA00004B" "url" => "/11301473/0000000100000001/v1_201305150952/S1130147390709451/v1_201305150952/es/main.assets" ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Meningioma secretor. Correlación clínicopatológica y revisión de la literatura" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "28" "paginaFinal" => "34" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "T. Alvaro, D. Aguilar, J. Aneiros, M.A. Arraez, J.M. Martín, M. Gómez-Morales, R. García del Moral" "autores" => array:7 [ 0 => array:2 [ "nombre" => "T." "apellidos" => "Alvaro" ] 1 => array:2 [ "nombre" => "D." "apellidos" => "Aguilar" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Aneiros" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "Arraez" ] 4 => array:2 [ "nombre" => "J.M." "apellidos" => "Martín" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Gómez-Morales" ] 6 => array:2 [ "nombre" => "R." "apellidos" => "García del Moral" ] ] "afiliaciones" => array:2 [ 0 => array:1 [ "entidad" => "Departamento de Anatomía Patológica. Hospital Clínico Universitario. Granada" ] 1 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital Virgen de las Nieves. Granada" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156520" "palabras" => array:4 [ 0 => "Meningioma" 1 => "Meningioma secretor" 2 => "Microscopia electrónica" 3 => "Inmunohistoquímica" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec156519" "palabras" => array:4 [ 0 => "Meningioma" 1 => "Secretory meningioma" 2 => "Ultrastructure" 3 => "Inmunohistochemistry" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El término meningioma secretor corresponde a un subtipo de meningioma cuyas características histopatológicas están representadas por un patrón sincitial, presencia difusa de inclusiones hialinas e hiperplasia pericitaria focal. Los hallazgos ultraestructurales e inmunohistoquímicos revelan la máxima expresión de la conocida bipotencialidad, mesenquimal y epitelial, del meningioma. Estas peculiaridades morfológicas se acompañan de una mayor rapidez de presentación clínica y un intenso edema peritumoral, que lo hace difícilmente reconocible como meningioma.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El hallazgo de antígeno carcinoembrionario (CEA) a nivel del tejido tumoral apunta la posibilidad de utilizar este marcador a nivel sérico y de LCR en el seguimiento de estos enfermos, así como incluir al meningioma secretor en el diagnóstico diferencial de pacientes con niveles de CEA elevados.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Secretory meningioma is the term given to a kind of meningioma characterized histologically by a meningothelial growth pattern, the presence of hyaline inclusions diffusely distributed throughout the tumour and focal pericytic hyperplasia. Ultrastructural and inmunohistochemical findings show the highest occurrence of the well-know bipotential capability of differentiation —epithelial and mesenchymal— of meningiomas. This tumour is often accompanied by cerebral edema and a rapid evolution of symptons, making the clinical diagnosis of meningioma difficult.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The positive staining of neoplastic cells for carcinoembrionic antigen (CEA) suggests the possibility of using this marker not only in the serum but also in the C.S.F. for the follow-up of patients harboring secretory meningioma, and stresses the necessity of including this tumour in the differential diagnosis of patients with a high level of CEA in their sera.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:36 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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