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array:23 [ "pii" => "S1130147305704188" "issn" => "11301473" "doi" => "10.1016/S1130-1473(05)70418-8" "estado" => "S300" "fechaPublicacion" => "2005-01-01" "aid" => "70418" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "2005" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2005;16:134-41" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4216 "formatos" => array:3 [ "EPUB" => 19 "HTML" => 1241 "PDF" => 2956 ] ] "itemSiguiente" => array:18 [ "pii" => "S113014730570419X" "issn" => "11301473" "doi" => "10.1016/S1130-1473(05)70419-X" "estado" => "S300" "fechaPublicacion" => "2005-01-01" "aid" => "70419" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Neurocirugia. 2005;16:141" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1690 "formatos" => array:3 [ "EPUB" => 17 "HTML" => 937 "PDF" => 736 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Comentario al trabajo: <span class="elsevierStyleItalic">Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptina y efedrina. Revisión fisiopatológica</span> de Mateo-Sierra y cols" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "141" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Brell" "autores" => array:1 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Brell" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S113014730570419X?idApp=UINPBA00004B" "url" => "/11301473/0000001600000002/v1_201305151236/S113014730570419X/v1_201305151236/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147305704176" "issn" => "11301473" "doi" => "10.1016/S1130-1473(05)70417-6" "estado" => "S300" "fechaPublicacion" => "2005-01-01" "aid" => "70417" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 2005;16:124-33" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3213 "formatos" => array:3 [ "EPUB" => 18 "HTML" => 2191 "PDF" => 1004 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Síndromes de hiperdrenaje de las válvulas en hidrocefalia infantil" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "124" "paginaFinal" => "133" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Syndromes of overdrainage of ventricular shunting in childhood hydrocephalus" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.F. Martínez-Lage, M.A. Pérez-Espejo, M.J. Almagro, J. Ros de San Pedro, F. López, C. Piqueras, J. Tortosa" "autores" => array:7 [ 0 => array:2 [ "nombre" => "J.F." "apellidos" => "Martínez-Lage" ] 1 => array:2 [ "nombre" => "M.A." "apellidos" => "Pérez-Espejo" ] 2 => array:2 [ "nombre" => "M.J." "apellidos" => "Almagro" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Ros de San Pedro" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "López" ] 5 => array:2 [ "nombre" => "C." "apellidos" => "Piqueras" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Tortosa" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147305704176?idApp=UINPBA00004B" "url" => "/11301473/0000001600000002/v1_201305151236/S1130147305704176/v1_201305151236/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "titulo" => "Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptina y efedrina. Revisión fisiopatológica" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "134" "paginaFinal" => "141" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "O. Mateo-Sierra, F.A. Gutiérrez, C. Fernández-Carballal, D. Pinilla, B. Mosqueira, B. Iza, R. Carrillo" "autores" => array:7 [ 0 => array:3 [ "nombre" => "O." "apellidos" => "Mateo-Sierra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "F.A." "apellidos" => "Gutiérrez" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Fernández-Carballal" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Pinilla" ] 4 => array:2 [ "nombre" => "B." "apellidos" => "Mosqueira" ] 5 => array:2 [ "nombre" => "B." "apellidos" => "Iza" ] 6 => array:2 [ "nombre" => "R." "apellidos" => "Carrillo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital General Universitario Gregorio Marañón. Madrid" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia postal: Servicio de Neurocirugía. Hospital General Universitario “Gregorio Mara-ñón”. C/Dr. Esquerdo 46. 28007-Madrid." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Akinetic mutism related to hydrocephalus and cerebellar surgery treated with bromocriptine and ephedrine. A pathophysiological review" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-06-03" "fechaAceptado" => "2004-08-18" "PalabrasClave" => array:2 [ "es" => array:2 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec158817" "palabras" => array:5 [ 0 => "Mutismo acinético" 1 => "Bromocriptina" 2 => "Agonista dopaminérgico" 3 => "Fosa posterior" 4 => "Hidrocefalia" ] ] 1 => array:4 [ "clase" => "abr" "titulo" => "Abreviaturas" "identificador" => "xpalclavsec158815" "palabras" => array:5 [ 0 => "AM" 1 => "MA" 2 => "BC" 3 => "DUP" 4 => "GCS" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec158816" "palabras" => array:5 [ 0 => "Akinetic mutism" 1 => "Bromocriptine" 2 => "Dopa-mine agonist" 3 => "Posterior fossa" 4 => "Hydrocephalus" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El mutismo acinético (MA) es un trastorno del comportamiento, caracterizado por la incapacidad para moverse o hablar en pacientes despiertos. Típicamente ha sido descrito como una complicación transitoria de la cirugía de tumores de fosa posterior. Sin embargo, el MA también puede aparecer tras múltiples fallos valvulares en pacientes hidrocefálicos. En estos casos, el MA no mejora espontáneamente, ni con revisiones valvulares, pero puede responder al tratamiento con bromocriptina. Presentamos una paciente con MA tras una cirugía de fosa posterior, complicada por una ventriculitis con dilataciones ventriculares repetidas, que sólo mejoró con bromocriptina. Revisamos la flsiopatología del MA. Aunque ésta no sea bien conocida, parece que la afectación del núcleo dentado y de sus eferencias (principalmente de glutamato) sería responsable del MA de origen cerebeloso, mientras que la afectación de las vías monoaminérgicas paraventri-culares explicaría el MA relacionado con dilataciones ventriculares repetidas y que responde al tratamiento con bromocriptina. Aun así, se requiere un estudio más profundo de esta patología para aclarar su etiología.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Akinetic mutism (AM) is a behavioral disorder characterized by impossibility to move or speak in awake patients. lt has been typically described as a transient disorder following posterior fossa tumour resection. Besides, AM may also appear after recurrent shunt failures in hydrocephalic patients, with no tendency towards improvement, either spontaneously or with shunt revisions. However successful treatment of this second type of AM has been achieved with bromocriptine. We present a patient who developed AM after a posterior fossa surgery complicated by ventriculitis and múltiple hydrocephalic events. AM only improved with bromocriptine. We review AM pathophysiology. Although not well known, it appears to be quite different, depending on its cerebellar or hydrocephalic origin. Damage to dentate nucleus or its efferents (mainly of glutamate) should promote AM of cerebellar origin, while damage to paraventricular monoaminergic pathways could explain AM related to repeated shunt failures which has successful response to bromocriptine treatment. However, a more complete study of this disorder is required to ascertain its aetiology.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Mateo-Sierra, O.; Gutiérrez, F.A.; Fernández-Carba-llal, C; Pinilla, D.; Mosqueira, B.; Iza, B.; Carrillo, F.: Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptma y efedrina. Revisión fisiopatológica. Neurocirugía 2005; 16: 134–141.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:28 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Akinetic mutism and progressive supranuclear palsy-like syndrome after the shunt of an obstructive hydrocephalus. Successful treatment with bromocriptine: 2 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Aidi" 1 => "B. Elalaoui-Faris" 2 => "A. Benomar" 3 => "M. Chaoui" 4 => "T. Chkili" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev. Neurol. (Paris)" "fecha" => "2000" "volumen" => "156" "paginaInicial" => "380" "paginaFinal" => "383" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." 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