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array:23 [ "pii" => "S1130147399707694" "issn" => "11301473" "doi" => "10.1016/S1130-1473(99)70769-4" "estado" => "S300" "fechaPublicacion" => "1999-01-01" "aid" => "70769" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1999" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1999;10:461-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2327 "formatos" => array:3 [ "EPUB" => 17 "HTML" => 981 "PDF" => 1329 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147399707700" "issn" => "11301473" "doi" => "10.1016/S1130-1473(99)70770-0" "estado" => "S300" "fechaPublicacion" => "1999-01-01" "aid" => "70770" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1999;10:466-70" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1989 "formatos" => array:3 [ "EPUB" => 16 "HTML" => 1026 "PDF" => 947 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Absceso bulbar: Presentación de un caso y revisión de la literatura" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "466" "paginaFinal" => "470" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Brain stem abcess. 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"apellidos" => "Moreno López" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399707700?idApp=UINPBA00004B" "url" => "/11301473/0000001000000006/v1_201305151018/S1130147399707700/v1_201305151018/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1130147399707682" "issn" => "11301473" "doi" => "10.1016/S1130-1473(99)70768-2" "estado" => "S300" "fechaPublicacion" => "1999-01-01" "aid" => "70768" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1999;10:453-60" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2716 "formatos" => array:3 [ "EPUB" => 16 "HTML" => 1050 "PDF" => 1650 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Cirurgía estereotáxica no tratamento do abcesso cerebral" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "453" "paginaFinal" => "460" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Stereotactic surgery for the treatment of cerebral abcess" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "O.L. Alves, O. Gomes, S. Paranhos" "autores" => array:3 [ 0 => array:2 [ "nombre" => "O.L." "apellidos" => "Alves" ] 1 => array:2 [ "nombre" => "O." "apellidos" => "Gomes" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Paranhos" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147399707682?idApp=UINPBA00004B" "url" => "/11301473/0000001000000006/v1_201305151018/S1130147399707682/v1_201305151018/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Probable enfermedad de Whipple limitada al SNC. Caso clínico" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "461" "paginaFinal" => "465" ] ] "autores" => array:2 [ 0 => array:3 [ "autoresLista" => "A. Aparicio, J.L. Maestro, M. García-Bach, J. Borrás, F. Vila" "autores" => array:5 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Aparicio" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Maestro" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "García-Bach" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Borrás" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "Vila" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neurocirugía. Hospital de Mutua de Terrassa. Terrassa (Barcelona)" ] ] ] 1 => array:3 [ "autoresLista" => "A. Salas, C. Sánchez, G. González, J. Casalots" "autores" => array:4 [ 0 => array:3 [ "nombre" => "A." "apellidos" => "Salas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] 2 => array:3 [ "nombre" => "G." "apellidos" => "González" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Casalots" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Anatomía Patológica. Hospital de Mutua de Terrassa. Terrassa (Barcelona)" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna. Hospital de Mutua de Terrassa. Terrassa (Barcelona)" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Probable Whipple's disease confined to the CNS. Case report" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156828" "palabras" => array:5 [ 0 => "Enfermedad de Whipple" 1 => "Trimetoprim-Sulfometoxazol (TMP-SMX)" 2 => "Biopsia esterotáxica" 3 => "Macrófagos PAS positivo" 4 => "Tropheryma whippelii" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec156829" "palabras" => array:6 [ 0 => "Whipple Disease" 1 => "Trimethoprim-Sulfamethoxazole" 2 => "(TMP-SMX)" 3 => "Stereotactic biopsy" 4 => "PAS positive macrophages" 5 => "Tropheryma whippelii" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La enfermedad de Whipple, es una enfermedad sistémica cuyas principales manifestaciones se localizan en el intestino delgado y articulaciones; la afectación primaria del SNC es infrecuente y de difícil diagnóstico cuando no se acompaña de artritis o sintomatología abdominal, más aún, si consideramos a las imágenes TAC y RM como inespecíficas. Presentamos un caso clínico de esta enfermedad, diagnosticado mediante biopsia estereotáxica y tratado a lo largo de 24 meses con Trimetoprim-Sulfametoxazol (TMP-SMX), con importante remisión de la sintomatología y desaparición de la lesión expansiva intracerebral.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The main symptomathology of systemic Wipple's disease is related with the small bowel and joints. Primary CNS involvement is very unusual and it is difficult to diagnose when arthritis ana abdominal symptons are not presento CT and MR images are not considered especific. We present a single case of Whipple's disease diagnosed by stereotactic biopsy and treated with Trimethoprim-Sulfamethoxazole (TMP-SMX) during a twenty-four months period. The patient showed significant remission of symptoms with dissaperance of the expansive cerebrallesion.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Aparicio, A.; Salas, A.; Maestro, J.L.; García-Bach, M.; Borrás, J.; Vila, F.; Sánchez, c.; González, G.; Casalots, J.: Probable enfermedad de Whipple limitada al SNC. Caso clínico. Neurocirugía 1999; 10: 461–465.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal mesenteric lymphatics tissues" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.H. 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