Journal Information
Vol. 33. Issue 4.
Pages 204-208 (July - August 2022)
Share
Share
Download PDF
More article options
Vol. 33. Issue 4.
Pages 204-208 (July - August 2022)
Caso clínico
Desarrollo de un linfoma cerebral con relación a un quiste epidermoide de larga evolución
Brain lymphoma development related to a long lasting epidermoid cyst
Angel Horcajadas Almansaa,
Corresponding author
angel.horcajadas@gmail.com

Autor para correspondencia.
, Ana M. Jorques Infantea, Clara E. Chamorro Santosb, Ana M. Román Cutillasa
a Servicio de Neurocirugía. Hospital Virgen de las Nieves. Granada. España
b Servicio de Anatomía Patológica. Hospital Virgen de las Nieves. Granada. España
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Resumen
Introducción

Los quistes epidermoides (QE) son lesiones de lento crecimiento y naturaleza benigna. Se presenta un caso de un desarrollo de un linfoma cerebral (LC) con relación a un tumor epidermoide, segundo caso descrito en la literatura.

Presentación del caso

Mujer de 40 años con QE intracraneal de larga evolución que desarrolla una lesión intraaxial rápidamente progresiva de acuerdo con dicho tumor. Tras la resección el diagnóstico es de linfoma primario difuso de células B.

Discusión

La transformación de QE a carcinomas de células escamosas ha sido reportado en contadas ocasiones, siendo el desarrollo de otras lesiones malignas conforme este proceso, absolutamente excepcional. Se han invocado mecanismos inflamatorios como la causa de dicha transformación. En la génesis de los linfomas están involucrados estos mecanismos y en el caso que nos ocupa, podría haber jugado un papel en el desarrollo del tumor.

Conclusiones

Aún siendo lesiones benignas, los QE tienen cierto potencial de malignización secundario a mecanismos de inflamación crónica.

Palabras clave:
Quiste epidermoide
Linfoma cerebral
Transformación maligna
Abstract
Introduction

Epidermoid cysts (EC) are benign and slow growing lesions. A primary brain lymphoma development related to a EC is presented, second case described in literature.

Case presentation

A woman 40 years old, harbouring a EC for more than 20 years, develops a fast growing brain lesion next to the EC. Surgery was performed and diagnosis was primary diffuse B cells lymphoma.

Discussion

Malignant transformation of EC has been described, usually to squamous cells carcinoma, and much less frequently, to another tumours. Inflammatory mechanisms have been advocated to explain this evolution. Chronic inflammation and lymphoma genesis are related, and this could be the mechanism behind this rare evolution of an EC.

Conclusions

Even being benign lesions, EC can develop malignant tumours due to the chronic inflammation secondary to them.

Keywords:
Epidermoid cyst
Brain lymphoma
Malignant transformation

Article

These are the options to access the full texts of the publication Neurocirugía (English edition)
Member
Member of the Sociedad Española de Neurocirugía

If it is the first time you have accessed you can obtain your credentials by contacting Elsevier Spain in suscripciones@elsevier.com or by calling our Customer Service at902 88 87 40 if you are calling from Spain or at +34 932 418 800 (from 9 to 18h., GMT + 1) if you are calling outside of Spain.

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option ¿I have forgotten my password¿.

Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Neurocirugía (English edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Neurocirugía (English edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?