array:23 [
  "pii" => "S1130147397710303"
  "issn" => "11301473"
  "doi" => "10.1016/S1130-1473(97)71030-3"
  "estado" => "S300"
  "fechaPublicacion" => "1997-01-01"
  "aid" => "71030"
  "copyright" => "Sociedad Española de Neurocirugía"
  "copyrightAnyo" => "1997"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Neurocirugia. 1997;8:199-204"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 16979
    "formatos" => array:3 [
      "EPUB" => 20
      "HTML" => 3315
      "PDF" => 13644
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1130147397710315"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(97)71031-5"
    "estado" => "S300"
    "fechaPublicacion" => "1997-01-01"
    "aid" => "71031"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Neurocirugia. 1997;8:205-10"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2565
      "formatos" => array:3 [
        "EPUB" => 14
        "HTML" => 1063
        "PDF" => 1488
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Valoración de dos métodos para la medición de la presión intracraneal"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "205"
          "paginaFinal" => "210"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Evaluation of two methods for I.C.P. measure"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "M. Pérez-Márquez, L. Marruecos, A.J. Betbesé, J. Ballús, E. Bak, A. Net"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "M."
              "apellidos" => "Pérez-Márquez"
            ]
            1 => array:2 [
              "nombre" => "L."
              "apellidos" => "Marruecos"
            ]
            2 => array:2 [
              "nombre" => "A.J."
              "apellidos" => "Betbesé"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Ballús"
            ]
            4 => array:2 [
              "nombre" => "E."
              "apellidos" => "Bak"
            ]
            5 => array:2 [
              "nombre" => "A."
              "apellidos" => "Net"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "J. Molet"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Molet"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397710315?idApp=UINPBA00004B"
    "url" => "/11301473/0000000800000003/v1_201305151502/S1130147397710315/v1_201305151502/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1130147397710297"
    "issn" => "11301473"
    "doi" => "10.1016/S1130-1473(97)71029-7"
    "estado" => "S300"
    "fechaPublicacion" => "1997-01-01"
    "aid" => "71029"
    "copyright" => "Sociedad Española de Neurocirugía"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Neurocirugia. 1997;8:183-98"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 9461
      "formatos" => array:3 [
        "EPUB" => 19
        "HTML" => 3601
        "PDF" => 5841
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Tumores de región pineal: manejo, tratamiento quirúrgico y seguimiento de 21 casos"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "183"
          "paginaFinal" => "198"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Pineal region tumors. Management and outcome of 21 cases"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "S. Pardo, J.M. Fernández Villa, J. Molet, B. Oliver, P. Tresserras, P. Parés, F. Bartumeus"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "S."
              "apellidos" => "Pardo"
            ]
            1 => array:2 [
              "nombre" => "J.M."
              "apellidos" => "Fernández Villa"
            ]
            2 => array:2 [
              "nombre" => "J."
              "apellidos" => "Molet"
            ]
            3 => array:2 [
              "nombre" => "B."
              "apellidos" => "Oliver"
            ]
            4 => array:2 [
              "nombre" => "P."
              "apellidos" => "Tresserras"
            ]
            5 => array:2 [
              "nombre" => "P."
              "apellidos" => "Parés"
            ]
            6 => array:2 [
              "nombre" => "F."
              "apellidos" => "Bartumeus"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "Ll. Colomo"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Ll."
              "apellidos" => "Colomo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397710297?idApp=UINPBA00004B"
    "url" => "/11301473/0000000800000003/v1_201305151502/S1130147397710297/v1_201305151502/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Daño axonal difuso: factores pronósticos clínico-epidemiológicos"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "199"
        "paginaFinal" => "204"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "R. Prat Acín, V. Calatayud Maldonado"
        "autores" => array:2 [
          0 => array:2 [
            "nombre" => "R."
            "apellidos" => "Prat Acín"
          ]
          1 => array:2 [
            "nombre" => "V."
            "apellidos" => "Calatayud Maldonado"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Hospital Clínico Universitario de Zaragoza. Servicio de Neurocirugía. Cátedra de Neurocirugía. Universidad de Zaragoza"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Diffuse axonal injury: clinical and epidemiological prognostic factors"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec163173"
          "palabras" => array:3 [
            0 => "DAD"
            1 => "Lesión cerebral difusa"
            2 => "Traumatismo craneoencefálico cerrado"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec163172"
          "palabras" => array:3 [
            0 => "Diffuse axonal injury"
            1 => "Diffuse brain injury"
            2 => "Closed head injury"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Un total de 140 pacientes con criterios cl&#237;nico radiol&#243;gicos de DAD fueron estudiados durante el per&#237;odo 1990&#8211;1994&#46; Analizamos en esta poblaci&#243;n las caracter&#237;sticas cl&#237;nicas y epidemiol&#243;gicas m&#225;s relevantes y su significaci&#243;n pron&#243;stica en este cuadro patol&#243;gico&#46; Predominaron los pacientes de sexo masculino y de edades comprendidas entre los 35 y los 60 a&#241;os que sufrieron un accidente de tr&#225;fico&#44; aspectos que no se relacionaron con un peor pron&#243;stico&#46; La existencia de anormalidades pupilares&#44; una menor puntuaci&#243;n en la Escala de coma de Glasgow &#40;E&#46;C&#46;G&#46;&#41;&#44; o la no percepci&#243;n de signos de d&#233;ficit neurol&#243;gico se asociaron con una peor evoluci&#243;n cl&#237;nica&#46; Se discute la relaci&#243;n de los distintos factores con la E&#46;C&#46;G&#46; y con el estado cl&#237;nico final&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The authors report the clinical and radiological presentation in 140 head injury patients diagnosed of diffuse axonal injury during the period 1990&#8211;1994&#46; The clinical and epidemiological aspects and their influence on the final outcome are described&#46; Most patients were males of ages between 35 and 60 years&#44; who had suffered traffic road accidents&#46; Nevertheless&#44; the age of the patient and the mechanism of trauma were not associated with a poorer outcome&#44; while pupillary ubnormalities and the worst G&#46;C&#46;S&#46; score&#44; did&#46; A variety of clinical and epidemiological factors and their relationship with G&#46;C&#46;S&#46; and with the final outcome were studied&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Prat Ac&#237;n&#44; R&#46;&#59; Calatayud Maldonado&#44; V&#46;&#58; Da&#241;o axonal difuso&#58; factores pron&#243;sticos cl&#237;nico-epidemiol&#243;gicos&#46; Neurocirug&#237;a 1997&#59; 8&#58; 199&#8211;204&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:30 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Difuse axonal injury in head injury&#58; definition&#44; diagnosis and grading"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;H&#46; Adams"
                            1 => "D&#46; Doyle"
                            2 => "I&#46; Ford"
                            3 => "T&#46;A&#46; Gennarelli"
                            4 => "D&#46;I&#46; Graham"
                            5 => "D&#46;R&#46; McLellan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Histopathology"
                        "fecha" => "1989"
                        "volumen" => "15"
                        "paginaInicial" => "49"
                        "paginaFinal" => "59"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2767623"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S187399460700075X"
                          "estado" => "S300"
                          "issn" => "18739946"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse axonal injury in head injuries caused by a fallo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;H&#46; Adams"
                            1 => "D&#46;I&#46; Graham"
                            2 => "D&#46; Doyle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(13)60649-2"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1984"
                        "volumen" => "22&#47;29"
                        "paginaInicial" => "1420"
                        "paginaFinal" => "1422"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23643112"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prediction tree for severely head-injured patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;C&#46; Choi"
                            1 => "L&#46;P&#46; Muzelaar"
                            2 => "T&#46;Y&#46; Barnes"
                            3 => "A&#46; Marmarou"
                            4 => "D&#46;M&#46; Brooks"
                            5 => "H&#46;F&#46; Young"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1991.75.2.0251"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg"
                        "fecha" => "1991"
                        "volumen" => "75"
                        "paginaInicial" => "251"
                        "paginaFinal" => "255"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2072162"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Commission on classification and terminology of the International League Against epilepsy&#58; proposal for revised clinical and EEG classification of epileptic seizures"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epilepsia"
                        "fecha" => "1981"
                        "volumen" => "22"
                        "paginaInicial" => "489"
                        "paginaFinal" => "501"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6790275"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of post-traumatic unawareness persisting for more than a month"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "I&#46; Dubroja"
                            1 => "S&#46; Valent"
                            2 => "P&#46; Miklic"
                            3 => "D&#46; Kesak"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurol Neurosurg Psychiatry"
                        "fecha" => "1995"
                        "volumen" => "58"
                        "paginaInicial" => "465"
                        "paginaFinal" => "466"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7738556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Axonal damage in severe traumatic brain injury&#58; an experimental study in cat"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46;E&#46; Erb"
                            1 => "J&#46;T&#46; Povlishock"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Neuropathol"
                        "fecha" => "1988"
                        "volumen" => "76"
                        "paginaInicial" => "347"
                        "paginaFinal" => "358"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2459896"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Th role of excitatory amino acids and NMDA receptors in traumatic brain injury"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;I&#46; Faden"
                            1 => "P&#46; Demediuk"
                            2 => "S&#46;S&#46; Panter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Science"
                        "fecha" => "1989"
                        "volumen" => "244"
                        "paginaInicial" => "798"
                        "paginaFinal" => "800"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2567056"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The influence of the type of intracraneal lesion on outcome from severe head injury&#58; a multicenter study using a new classification system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46;A&#46; Gennarelli"
                            1 => "G&#46; Spielman"
                            2 => "T&#46;W&#46; Langfitt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1982.56.1.0026"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg"
                        "fecha" => "1982"
                        "volumen" => "56"
                        "paginaInicial" => "26"
                        "paginaFinal" => "32"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7054419"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse axonal injury and traumatic coma in the primate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46;A&#46; Gennarelli"
                            1 => "L&#46;E&#46; Thibault"
                            2 => "J&#46;H&#46; Adams"
                            3 => "D&#46;I&#46; Graham"
                            4 => "C&#46;J&#46; Thompson"
                            5 => "R&#46;P&#46; Marcincin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/ana.410120611"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Neurol"
                        "fecha" => "1982"
                        "volumen" => "12"
                        "paginaInicial" => "564"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7159060"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse axonal injury in the primate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "T&#46;A&#46; Gennarelli"
                            1 => "L&#46;E&#46; Tribault"
                            2 => "J&#46;H&#46; Adams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Trauma of the Central Nervous System"
                        "paginaInicial" => "169"
                        "paginaFinal" => "194"
                        "serieFecha" => "1985"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathophysiologic rsponses to rotational and translational acceleration of the head"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;A&#46; Gennarelli"
                            1 => "L&#46;E&#46; Thibault"
                            2 => "A&#46;K&#46; Ommaya"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "16th Stapp Car Crash Conference"
                        "paginaInicial" => "296"
                        "paginaFinal" => "308"
                        "serieFecha" => "1972"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cerebral concussion and diffuse brain injuries"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;A&#46; Gennarelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Head Injury"
                        "paginaInicial" => "137"
                        "paginaFinal" => "159"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Head injury in man and experimental animals&#46; Clinical aspects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;A&#46; Gennarelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Neurochir"
                        "fecha" => "1983"
                        "volumen" => "32"
                        "numero" => "Suppl"
                        "paginaInicial" => "1"
                        "paginaFinal" => "13"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The distribution&#44; nature and time course of diffuse axonal injury"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;I&#46; Graham"
                            1 => "J&#46;H&#46; Adams"
                            2 => "S&#46; Logan"
                            3 => "T&#46;A&#46; Gennarelli"
                            4 => "L&#46; Thibault"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Neuropathol&#46; Appl&#46; Neurobiol&#46;"
                        "fecha" => "1985"
                        "volumen" => "11"
                        "paginaInicial" => "319"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of head injury in 2298 patients treated in a single clinic during a 21-year period"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Gordon"
                            1 => "H&#46; von Holst"
                            2 => "A&#46; Rudehill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg Anesthesiol"
                        "fecha" => "1995"
                        "volumen" => "7"
                        "paginaInicial" => "235"
                        "paginaFinal" => "247"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8563443"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mechanics of head injuries"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;H&#46;S&#46; Holbourn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1943"
                        "volumen" => "2"
                        "paginaInicial" => "438"
                        "paginaFinal" => "441"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11644433"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Technetium-99m- HMPAO SPECT&#44; CT&#44; and MRI in the evaluation of patients with chronic traumatic brain injury&#58; a correlation with neuropsychological performance"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Ichise"
                            1 => "D&#46;G&#46; Chung"
                            2 => "P&#46; Wang"
                            3 => "G&#46; Wortzman"
                            4 => "B&#46;G&#46; Gray"
                            5 => "W&#46; Franks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "1994"
                        "volumen" => "35"
                        "paginaInicial" => "217"
                        "paginaFinal" => "226"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8294988"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S014067361060551X"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Head trauma&#58; comparison of MR and CT experience in 100 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;B&#46; Kelly"
                            1 => "R&#46;D&#46; Zimmermann"
                            2 => "R&#46;B&#46; Snow"
                            3 => "S&#46;E&#46; Gandy"
                            4 => "L&#46;A&#46; Heier"
                            5 => "M&#46;D&#46;F&#46; Deck"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AJNR"
                        "fecha" => "1988"
                        "volumen" => "9"
                        "paginaInicial" => "699"
                        "paginaFinal" => "708"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3135716"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse axonal injury&#58; analysis of 100 patients with radiological signs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Levi"
                            1 => "J&#46;N&#46; Guilburd"
                            2 => "A&#46; Lemberger"
                            3 => "J&#46;F&#46; Soustiel"
                            4 => "M&#46; Feinsod"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "neurosurgery"
                        "fecha" => "1990"
                        "volumen" => "27"
                        "paginaInicial" => "429"
                        "paginaFinal" => "432"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2234337"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome from severe head injury related to the type of intracraneal 1esion&#58; A computerized tomography study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;D&#46; Lobato"
                            1 => "F&#46; Cordob&#233;s"
                            2 => "J&#46;J&#46; Rivas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1983.59.5.0762"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg"
                        "fecha" => "1983"
                        "volumen" => "59"
                        "paginaInicial" => "762"
                        "paginaFinal" => "774"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6619928"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prediction of motor status 3 and 6 months post severe traumatic brain injury&#58; a preliminary study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46; Macpherson"
                            1 => "S&#46;J&#46; Sullivan"
                            2 => "J&#46; Lambert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brain Inj"
                        "fecha" => "1992"
                        "volumen" => "6"
                        "paginaInicial" => "489"
                        "paginaFinal" => "498"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1393183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The National Traumatic Coma Data Bank&#46; Part 1&#58; Design&#44; purpose goals&#44; and results"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "L&#46;F&#46; Marshall"
                            1 => "D&#46;P&#46; Becker"
                            2 => "S&#46;A&#46; Bowers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1983.59.2.0276"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg"
                        "fecha" => "1983"
                        "volumen" => "59"
                        "paginaInicial" => "276"
                        "paginaFinal" => "284"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6345728"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognosis for recovery from prolonged posttraumatic unawareness&#58; logistic analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Sazbon"
                            1 => "C&#46; Fuchs"
                            2 => "H&#46; Costeff"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Nurol Nurosurg Psychiatry"
                        "fecha" => "1991"
                        "volumen" => "54"
                        "paginaInicial" => "149"
                        "paginaFinal" => "152"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "CT sean in severe diffuse head injury&#58; physiological and clinical correlations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Tasdale"
                            1 => "E&#46; Cardoso"
                            2 => "S&#46; Galbraith"
                            3 => "G&#46; Teasdale"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurol Neurosurg Psychiat"
                        "fecha" => "1984"
                        "volumen" => "47"
                        "paginaInicial" => "600"
                        "paginaFinal" => "603"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6736993"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of coma and impaired conciousness&#58; a practical scale"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Teasdale"
                            1 => "B&#46; Jennet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1984"
                        "volumen" => "2"
                        "paginaInicial" => "81"
                        "paginaFinal" => "84"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2567876"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Classification and regression trees &#40;CART&#41; for prediction of function at 1 year following head trauma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46;R&#46; Temkin"
                            1 => "R&#46; Holubkov"
                            2 => "J&#46;E&#46; Machamer"
                            3 => "H&#46;R&#46; Winn"
                            4 => "S&#46;S&#46; Dikmen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1995.82.5.0764"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg&#46;"
                        "fecha" => "1995"
                        "volumen" => "82"
                        "paginaInicial" => "764"
                        "paginaFinal" => "771"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7714600"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comprehensive predictions of outcome in closed head-injured patients&#46; The development of prognostic equations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;W&#46; Thatcher"
                            1 => "D&#46;S&#46; Cantor"
                            2 => "R&#46; McAlaster"
                            3 => "F&#46; Geisler"
                            4 => "P&#46; Krause"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann N Y Acad Sci"
                        "fecha" => "1991"
                        "volumen" => "62"
                        "paginaInicial" => "82"
                        "paginaFinal" => "101"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Posttraumatic diffuse cerebral lesions&#46; Relationship between clinical course&#44; CT findings and ICP"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "G&#46; Tomei"
                            1 => "Sganzerla"
                            2 => "D&#46; Spagnoli"
                            3 => "P&#46; Guerra"
                            4 => "C&#46; Lucarini"
                            5 => "S&#46;M&#46; Gaini"
                            6 => "R&#46; Villani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurosurg Sci"
                        "fecha" => "1991"
                        "volumen" => "35"
                        "paginaInicial" => "61"
                        "paginaFinal" => "75"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1757805"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Head injury&#44; a multivariate study&#58; predicting long-term productivity and independent living outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;R&#46; Vogenthaler"
                            1 => "K&#46;R&#46; Smith Jr&#46;"
                            2 => "P&#46; Goldfader"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brain Inj"
                        "fecha" => "1989"
                        "volumen" => "3"
                        "paginaInicial" => "369"
                        "paginaFinal" => "385"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2819317"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acute tissue tear hemorrhages of the brain&#58; Computed tomography and clinicopathological correlations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;E&#46; Wilberger Jr&#46;"
                            1 => "W&#46;E&#46; Rothfus"
                            2 => "J&#46; Tabas"
                            3 => "A&#46;L&#46; Goldberg"
                            4 => "Z&#46;L&#46; Deeb"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurosurgery"
                        "fecha" => "1990"
                        "volumen" => "27"
                        "paginaInicial" => "208"
                        "paginaFinal" => "213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2385338"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/11301473/0000000800000003/v1_201305151502/S1130147397710303/v1_201305151502/es/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/11301473/0000000800000003/v1_201305151502/S1130147397710303/v1_201305151502/es/main.pdf?idApp=UINPBA00004B&text.app=https://revistaneurocirugia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397710303?idApp=UINPBA00004B"
]
Share
Journal Information
Vol. 8. Issue 3.
Pages 199-204 (January 1997)
Share
Share
Download PDF
More article options
Vol. 8. Issue 3.
Pages 199-204 (January 1997)
Daño axonal difuso: factores pronósticos clínico-epidemiológicos
Diffuse axonal injury: clinical and epidemiological prognostic factors
Visits
16984
R. Prat Acín, V. Calatayud Maldonado
Hospital Clínico Universitario de Zaragoza. Servicio de Neurocirugía. Cátedra de Neurocirugía. Universidad de Zaragoza
This item has received
Article information
Resumen

Un total de 140 pacientes con criterios clínico radiológicos de DAD fueron estudiados durante el período 1990–1994. Analizamos en esta población las características clínicas y epidemiológicas más relevantes y su significación pronóstica en este cuadro patológico. Predominaron los pacientes de sexo masculino y de edades comprendidas entre los 35 y los 60 años que sufrieron un accidente de tráfico, aspectos que no se relacionaron con un peor pronóstico. La existencia de anormalidades pupilares, una menor puntuación en la Escala de coma de Glasgow (E.C.G.), o la no percepción de signos de déficit neurológico se asociaron con una peor evolución clínica. Se discute la relación de los distintos factores con la E.C.G. y con el estado clínico final.

Palabras clave:
DAD
Lesión cerebral difusa
Traumatismo craneoencefálico cerrado
Summary

The authors report the clinical and radiological presentation in 140 head injury patients diagnosed of diffuse axonal injury during the period 1990–1994. The clinical and epidemiological aspects and their influence on the final outcome are described. Most patients were males of ages between 35 and 60 years, who had suffered traffic road accidents. Nevertheless, the age of the patient and the mechanism of trauma were not associated with a poorer outcome, while pupillary ubnormalities and the worst G.C.S. score, did. A variety of clinical and epidemiological factors and their relationship with G.C.S. and with the final outcome were studied.

Key words:
Diffuse axonal injury
Diffuse brain injury
Closed head injury

Article

These are the options to access the full texts of the publication Neurocirugía (English edition)
Member
Member of the Sociedad Española de Neurocirugía

If it is the first time you have accessed you can obtain your credentials by contacting Elsevier Spain in suscripciones@elsevier.com or by calling our Customer Service at902 88 87 40 if you are calling from Spain or at +34 932 418 800 (from 9 to 18h., GMT + 1) if you are calling outside of Spain.

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option ¿I have forgotten my password¿.

Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Neurocirugía (English edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Neurocirugía (English edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?