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array:22 [ "pii" => "S1130147397710510" "issn" => "11301473" "doi" => "10.1016/S1130-1473(97)71051-0" "estado" => "S300" "fechaPublicacion" => "1997-01-01" "aid" => "71051" "copyright" => "Sociedad Española de Neurocirugía" "copyrightAnyo" => "1997" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1997;8:5-15" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1764 "formatos" => array:3 [ "EPUB" => 18 "HTML" => 789 "PDF" => 957 ] ] "itemSiguiente" => array:18 [ "pii" => "S1130147397710522" "issn" => "11301473" "doi" => "10.1016/S1130-1473(97)71052-2" "estado" => "S300" "fechaPublicacion" => "1997-01-01" "aid" => "71052" "copyright" => "Sociedad Española de Neurocirugía" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Neurocirugia. 1997;8:16-24" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 12830 "formatos" => array:3 [ "EPUB" => 19 "HTML" => 2538 "PDF" => 10273 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Tratamiento no quirúrgico de los hematomas epidurales y subdurales de pequeño y mediano tamaño. Criterios para la selección y seguimiento de los pacientes" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "16" "paginaFinal" => "24" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R.D. Lobato, F. Servadei, P.A. Gómez, P. González" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R.D." "apellidos" => "Lobato" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Servadei" ] 2 => array:2 [ "nombre" => "P.A." "apellidos" => "Gómez" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "González" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1130147397710522?idApp=UINPBA00004B" "url" => "/11301473/0000000800000001/v1_201305151458/S1130147397710522/v1_201305151458/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Valor da histopatologia e da cinética celular no prognóstico dos tumores gliais" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "5" "paginaFinal" => "15" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J. Pimentel" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Pimentel" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Laboratório de Neuropatología. Servíço de Neurología. Hospital de Santa Maria. Lisboa" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras chave" "identificador" => "xpalclavsec163061" "palabras" => array:5 [ 0 => "Gliomas" 1 => "Histopatologia" 2 => "Classificação dos gliomas" 3 => "Biópsia estereotáxica" 4 => "Cinética celular" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec163060" "palabras" => array:5 [ 0 => "Gliomas" 1 => "Histopathology" 2 => "Classification of gliomas" 3 => "Stereotactic biopsy" 4 => "Cell kinetics" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">O autor revê o valor da histopatologia e da cinética das células tumorais no prognóstico dos tumores gliais. Aspectos microscópicos como sejam a infiltração dos tecidos vizinhos ou para lá dos confins do tumor e a constatado de multifocalidade tumoral são factores importantes na recorrência dos gliomas objecto de recessóes macroscópicas totais. As classificações histopatológicas destes tumores associadas a tentativa de correlac,ao clínica sao revistas criticamente. É realçada a importância da biópsia estereotáxica no diagnóstico histológico e na opção terapêutica dos gliomas. Os métodos de avaliação prática da capacidade proliferativa das células tumorais são a determinação dos índices proliferativos do PCNA, Ki-67 e MIB1, que se correlacionam com o comportamento biológico dos gliomas.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The author reviews the value of the histology and tumor cell kinetics in the prognostic of gliomas. Microscopic features like infiltration of perilesional tissue or beyond the immediate confines of the growth, and occurrence of multifocality are important factors to tumor's recurrences after macroscopically total resections. Histopathological classifications of gliomas attempting a correlation with their prognostic are critically reviewed. The importance of stereotactic biopsy in the histological diagnosis and therapeutic approach of gliomas is stressed. The routine methods of evaluation of the proliferative capacity of tumoral cells are the PCNA, Ki-67 and MIB1 index labellings, which correlate with the clinical behaviour of gliomas.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Pimentel, J.: Valor da histopatologia e da cinética celular no prognóstico dos tumores gliais 1997; 8: 5–15.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is necrosis helpful in the grading of gliomas? Editorial opinion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E.C. Alvord Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J. Neuropathol. 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Year/Month | Html | Total | |
---|---|---|---|
2023 March | 0 | 2 | 2 |
2018 February | 8 | 6 | 14 |
2018 January | 12 | 5 | 17 |
2017 December | 19 | 4 | 23 |
2017 November | 45 | 14 | 59 |
2017 October | 7 | 8 | 15 |
2017 September | 16 | 20 | 36 |
2017 August | 18 | 20 | 38 |
2017 July | 15 | 11 | 26 |
2017 June | 19 | 8 | 27 |
2017 May | 26 | 9 | 35 |
2017 April | 13 | 11 | 24 |
2017 March | 13 | 0 | 13 |
2017 February | 7 | 1 | 8 |
2017 January | 9 | 5 | 14 |
2016 December | 27 | 20 | 47 |
2016 November | 17 | 4 | 21 |
2016 October | 27 | 21 | 48 |
2016 September | 38 | 9 | 47 |
2016 August | 43 | 20 | 63 |
2016 July | 26 | 11 | 37 |
2015 December | 3 | 0 | 3 |
2015 June | 16 | 10 | 26 |
2015 May | 19 | 17 | 36 |
2015 April | 11 | 18 | 29 |
2015 March | 14 | 26 | 40 |
2015 February | 11 | 34 | 45 |
2015 January | 14 | 17 | 31 |
2014 December | 10 | 25 | 35 |
2014 November | 11 | 20 | 31 |
2014 October | 17 | 29 | 46 |
2014 September | 7 | 29 | 36 |
2014 August | 9 | 28 | 37 |
2014 July | 13 | 35 | 48 |
2014 June | 7 | 33 | 40 |
2014 May | 11 | 29 | 40 |
2014 April | 15 | 21 | 36 |
2014 March | 8 | 25 | 33 |
2014 February | 10 | 30 | 40 |
2014 January | 10 | 17 | 27 |
2013 December | 8 | 25 | 33 |
2013 November | 16 | 18 | 34 |
2013 October | 14 | 19 | 33 |
2013 September | 12 | 22 | 34 |
2013 August | 23 | 22 | 45 |
2013 July | 15 | 22 | 37 |
2013 June | 11 | 28 | 39 |
2013 May | 11 | 30 | 41 |
2013 April | 9 | 19 | 28 |
2013 March | 11 | 23 | 34 |
2013 February | 7 | 23 | 30 |
2013 January | 15 | 9 | 24 |
2012 December | 11 | 18 | 29 |
2012 November | 0 | 15 | 15 |
2012 October | 0 | 9 | 9 |
2012 September | 0 | 5 | 5 |
2012 January | 5 | 0 | 5 |