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    "titulo" => "Adenomas hipofisarios secretores de hormona do crescimento. Uma análise clínica, endocrinológica, imagiológica, neuro-oftalmológica e cirúrgica de 32 casos operados"
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        "titulo" => "Sum&#225;rio"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A hip&#243;fise &#233; o local de origem de 15&#37; dos tumores intracranianos&#46; Os adenomas hipofis&#225;rios secretores de hormona do crescimento &#40;GH&#41; estao associados a sintomas e sinais com repercussao sist&#233;mica e consequentemente tem influencia a n&#237;vel da qualidade de vida e sua longevidade&#46; Os autores fazem um estudo retrospectivo de 32 adenomas secretores de GH operados no Servi&#231;o de Neurocirurgica do Hospital Geral de Santo Ant&#243;nio de Janeiro de 1987 a Dezembro de 1996&#46; &#201; realizada uma an&#225;lise cl&#237;nica&#44; imagiol&#243;gica&#44; endocrinol&#243;gica e neuro-oftalmol&#243;gica&#46; &#201; feito tamb&#233;m um estudo comparativo com a literatura&#46;</p>"
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Pituitary adenomas are known as representing 15&#37; of all intracranial tumours&#46; Growth hormone secreting pituitary adenomas are associated with symptoms and signs with systemic repercussion and deleterious effects on quality and expectation of life&#46; The authors performed a retrospective analysis of 32 patients operated on GH adenomas between January&#47;1987 and December&#47;1996 at the Neurosurgical Service of the Hospital Geral de Santo Ant&#243;nio&#44; Porto&#46; We commenton the clinic&#44; imaging&#44; endocrinologic and neuro-ophtalmologic stuies&#46; A comparative study with data reported in the literature is also done&#46;</p>"
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                            2 => "E&#46; Elliott"
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                            2 => "D&#46; L&#252;decke"
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                        ]
                      ]
                    ]
                  ]
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                        "paginaInicial" => "677"
                        "paginaFinal" => "684"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7596496"
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                          ]
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                      ]
                    ]
                  ]
                ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients"
                      "autores" => array:1 [
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                          "autores" => array:2 [
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                        ]
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                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.3171/jns.1988.68.6.0854"
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                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1988"
                        "volumen" => "68"
                        "paginaInicial" => "854"
                        "paginaFinal" => "867"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3373281"
                            "web" => "Medline"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transsphenoidal microhypophysectomy in acromegaly"
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                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Sang"
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                            2 => "B&#46; Tyrrell"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3171/jns.1977.47.6.0840"
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                        "tituloSerie" => "J&#46; Neurosurg"
                        "fecha" => "1977"
                        "volumen" => "47"
                        "paginaInicial" => "840"
                        "paginaFinal" => "852"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/925741"
                            "web" => "Medline"
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                      ]
                    ]
                  ]
                ]
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            ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La selle turcique dans l&#39;acrom&#233;galie Etude radiologique &#8211;Acromegalie&#8211; gigantisme"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
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                            1 => "R&#46; Maltais"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurochirurgie"
                        "fecha" => "1973"
                        "volumen" => "19"
                        "paginaInicial" => "35"
                        "paginaFinal" => "56"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4356510"
                            "web" => "Medline"
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                  ]
                ]
              ]
            ]
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                    0 => array:2 [
                      "titulo" => "The treatment of acromegaly with special reference to transsphenoidal hypophysectomy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
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                            2 => "A&#46; Kurtz"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Q&#46;J&#46; Med"
                        "fecha" => "1975"
                        "volumen" => "44"
                        "paginaInicial" => "79"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1153691"
                            "web" => "Medline"
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                ]
              ]
            ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transsphenoidal microsurgical removal of 250 pituitary adenomas"
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                          "autores" => array:2 [
                            0 => "C&#46; Wilson"
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                        ]
                      ]
                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.3171/jns.1978.48.1.0013"
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                        "paginaInicial" => "13"
                        "paginaFinal" => "22"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/201736"
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                ]
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                    0 => array:2 [
                      "titulo" => "Mortality in acromegaly"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Wright"
                            1 => "D&#46; Hill"
                            2 => "C&#46; Lowy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
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                      "Revista" => array:7 [
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                        "paginaInicial" => "1"
                        "paginaFinal" => "16"
                        "link" => array:1 [
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Adenomas hipofisarios secretores de hormona do crescimento. Uma análise clínica, endocrinológica, imagiológica, neuro-oftalmológica e cirúrgica de 32 casos operados
Growth hormone secreting pituitary adenomas
C. Pinheiro, I. Ribeiro, L. Ramos
Servicos de Neurocirurgia. Hospital Geral de Santo António. Porto. Portugal
M.J. Oliveira*
* Servicos de Endocrinologia. Hospital Geral de Santo António. Porto. Portugal
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                          "autores" => array:4 [
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                            2 => "R&#46; Randall"
                            3 => "C&#46; Abboud"
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                      "titulo" => "Transsphenoidal surgery following unsuccessful prior therapy"
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                          "autores" => array:3 [
                            0 => "E&#46; Laws"
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                            2 => "M&#46; Redmond"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2997414"
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                      "titulo" => "Clinical and endocrinological evaluation of 16 acromegalic patients treated by transsphenoidal surgery"
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                          "autores" => array:4 [
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                            2 => "R&#46; Jesse"
                            3 => "R&#46; Byers"
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                      ]
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                        "paginaInicial" => "853"
                        "paginaFinal" => "860"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/411899"
                            "web" => "Medline"
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              ]
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                      "titulo" => "Novel features of tumors that secrete both growth hormone and prolactin in acromegaly"
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                        "paginaFinal" => "184"
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                        "paginaFinal" => "684"
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                        "tituloSerie" => "Neurochirurgie"
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                        "paginaInicial" => "35"
                        "paginaFinal" => "56"
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                  "host" => array:1 [
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                        "tituloSerie" => "Q&#46;J&#46; Med"
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                        "paginaInicial" => "79"
                        "paginaFinal" => "98"
                        "link" => array:1 [
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