Cordoma condroide: Presentación de un caso con características inmunohistoquímicas peculiares
Chondroid chordoma: a case report with unusual inmunohistochemical features
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"apellidos" => "Vera Román" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Anatomía Patológica. Hospital General de Castellón. Castellón" ] ] ] 1 => array:3 [ "autoresLista" => "J.A. Barcia Albacar, J.L. Gil Salú, J.M. González Darder" "autores" => array:3 [ 0 => array:3 [ "nombre" => "J.A." "apellidos" => "Barcia Albacar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "J.L." "apellidos" => "Gil Salú" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J.M." "apellidos" => "González Darder" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Sección de Neurocirugía. Hospital General de Castellón. Castellón" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Chondroid chordoma: a case report with unusual inmunohistochemical features" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156668" "palabras" => array:4 [ 0 => "Cordoma condroide" 1 => "Cordoma" 2 => "Condrosarcoma" 3 => "Tumores base cráneo" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec156667" "palabras" => array:4 [ 0 => "Chondroid chordoma" 1 => "Chordoma" 2 => "Chondrosarcoma" 3 => "Skull base tumors" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentarnos el caso de una mujer de 68 años con un cordoma condroide del peñasco derecho que se extendía extracranealmente por el agujero rasgado posterior. Inmunohistoquímicamente mostraba un perfil peculiar con positividad para vimentina, proteína S100, queratinas (AEl-AE3) y CEA, siendo negativo para EMA, fenotipo no descrito hasta ahora.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El cordoma condroide no está reconocido corno una entidad definida por todos los autores. Tiene rasgos morfológicos de cordoma y condrosarcoma, lo que se corrobora por su inmunofenotipia inmunohistoquímica, que es la de esos dos tipos de tumor. Ocurre mayormente en la base del cráneo, pero también en la región sacrocoxígea. Parece tener una mejor evolución que los cordomas convencionales, aunque el número de casos recogido en la literatura es todavía insuficiente para asegurarlo.</p>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We present a case of chondroid chordoma involving the petrous bone, with an extracranial extension through the yugular foramen in a 68 year-old woman. Immunohistochemical staining exhibited a positive reaction for vimentin, S-100 protein, keratin (AEl-AE3) and CEA, but lacked reactivity for EMA.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A chondroid chordoma is not an entity universally recognized. It has both the morfological features of chordoma and chondrosarcoma. This is also shown by its inmunohistochemical profile because shares the positivity of both tumors. Although mainly found at the cranium base it can also be found at the sacro-coccygeal region. It appears to have better prognosis than conventional chordoma but since there have been recorded too few cases it cannot be substantiated as yet.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Lázaro Santander, R; Vera Román, J.M.; Barcia Albacar, lA.; Gil Salú, J.L.; González Darder, J.M.: Cordoma condroide: Presentación de un caso con características inmunohistoquímicas peculiares. Neurocirugía 1999; 10: 158–162.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chordomas and cartilaginous tumors at the skull base" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.J. Heffelfinger" 1 => "D.C. Dahlin" 2 => "C.S. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 1 | 0 | 1 |
| 2023 March | 1 | 1 | 2 |
| 2018 February | 15 | 3 | 18 |
| 2018 January | 25 | 9 | 34 |
| 2017 December | 20 | 20 | 40 |
| 2017 November | 44 | 19 | 63 |
| 2017 October | 13 | 31 | 44 |
| 2017 September | 22 | 25 | 47 |
| 2017 August | 22 | 16 | 38 |
| 2017 July | 18 | 42 | 60 |
| 2017 June | 23 | 26 | 49 |
| 2017 May | 23 | 21 | 44 |
| 2017 April | 20 | 24 | 44 |
| 2017 March | 32 | 45 | 77 |
| 2017 February | 20 | 20 | 40 |
| 2017 January | 19 | 14 | 33 |
| 2016 December | 28 | 26 | 54 |
| 2016 November | 32 | 28 | 60 |
| 2016 October | 39 | 33 | 72 |
| 2016 September | 54 | 48 | 102 |
| 2016 August | 65 | 42 | 107 |
| 2016 July | 53 | 34 | 87 |
| 2016 May | 2 | 0 | 2 |
| 2016 April | 1 | 0 | 1 |
| 2016 January | 2 | 0 | 2 |
| 2015 December | 2 | 23 | 25 |
| 2015 October | 0 | 27 | 27 |
| 2015 September | 1 | 0 | 1 |
| 2015 August | 1 | 0 | 1 |
| 2015 July | 3 | 5 | 8 |
| 2015 June | 39 | 17 | 56 |
| 2015 May | 52 | 26 | 78 |
| 2015 April | 35 | 27 | 62 |
| 2015 March | 30 | 20 | 50 |
| 2015 February | 26 | 27 | 53 |
| 2015 January | 37 | 22 | 59 |
| 2014 December | 29 | 24 | 53 |
| 2014 November | 16 | 35 | 51 |
| 2014 October | 28 | 40 | 68 |
| 2014 September | 23 | 30 | 53 |
| 2014 August | 20 | 35 | 55 |
| 2014 July | 25 | 31 | 56 |
| 2014 June | 40 | 32 | 72 |
| 2014 May | 37 | 31 | 68 |
| 2014 April | 29 | 29 | 58 |
| 2014 March | 31 | 25 | 56 |
| 2014 February | 38 | 31 | 69 |
| 2014 January | 42 | 18 | 60 |
| 2013 December | 34 | 22 | 56 |
| 2013 November | 18 | 36 | 54 |
| 2013 October | 26 | 27 | 53 |
| 2013 September | 36 | 35 | 71 |
| 2013 August | 30 | 44 | 74 |
| 2013 July | 41 | 20 | 61 |
| 2013 June | 37 | 40 | 77 |
| 2013 May | 36 | 45 | 81 |
| 2013 April | 32 | 34 | 66 |
| 2013 March | 18 | 43 | 61 |
| 2013 February | 14 | 23 | 37 |
| 2013 January | 20 | 19 | 39 |
| 2012 December | 16 | 24 | 40 |
| 2012 November | 0 | 18 | 18 |
| 2012 October | 0 | 3 | 3 |
| 2012 September | 0 | 1 | 1 |
| 2012 January | 10 | 0 | 10 |
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