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Uncorrected Proof. Available online 15 December 2025
The experimental laboratory in the development and evolution of neurosurgery—Historical perspective in tribute to Professor G. Yasargil
El laboratorio experimental en el desarrollo y la evolución de la neurocirugía: perspectiva histórica en homenaje al profesor G. Yasargil
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Giancarlo Mattos Piaggio
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gmattospiaggio@gmail.com

Corresponding author.
, Emilio González Martínez, David Santamarta Gómez, Javier Ibáñez Plágaro, José García-Cosamalón
Servicio de Neurocirugía, Complejo Asistencial Universitario de León, León, Spain
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Abstract

The experimental laboratory has been of paramount importance in the development and evolution of neurosurgery. In that research environment, many neurosurgical techniques were designed and the classics approaches to different regions of the brain were refined, until turning neurological surgery into atraumatic procedure, fulfilling one of the founding axioms of this speciality, that of delicate treatment on brain tissue, advocated by Harvey Cushing and later optimized by Professor Gazy Yasargil. The scenarios, their main characters, and the contributions they made to the development and progress of neurosurgery have all been analyzed in this article from a historical standpoint.

Keywords:
John Hunter laboratory
Harvey Cushing
Peardon Donaghy
Gazy Yasargil
Resumen

El laboratorio experimental tuvo una importancia capital en el desarrollo y la evolución de la neurocirugía. En ese ambiente investigador se diseñaron muchas técnicas neuroquirúrgicas y se refinaron los accesos clásicos a diferentes regiones del cerebro, hasta llegar a convertir la cirugía neurológica en un procedimiento atraumático, cumpliéndose uno de los axiomas fundacionales de esta especialidad, el trato delicado del tejido cerebral, propugnado por Harvey Cushing y optimizado, más tarde, por el profesor Gazy Yasargil. Desde una perspectiva histórica, se han analizado los escenarios de investigación, los protagonistas y sus respectivas aportaciones al desarrollo y el progreso de la neurocirugía.

Palabras clave:
Laboratorio John Hunter
Harvey Cushing
Peardon Donaghy
Gazy Yasargil

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