An experimental study was performed in rats to evaluate the potential usefulness of the vicryl-collagen prosthesis in limiting epidural scar formation after laminectomy. The results obtained suggest that the presence of the prosthesis in the epidural space did not significantly influence the density or thickness of epidural scar tissue. Nevertheless, the fact that this material was well tolerated, being replaced by fibrous tissue without inflammatory tissular response, suggests that its use in the epidural space may be preferable to that of other absorbable materials and supports earlier studies suggesting the usefulness of the vicryl mesh as a dural substitute.
Se presenta un estudio experimental sobre ratas adultas, diseñado para evaluar la potencial utilidad de las prótesis de vicril-colágeno para limitar la formación de cicatrices epidurales tras la práctica de una laminectomía. Los resultados obtenidos sugieren que la presencia de este material en el espacio epidural raquídeo no influye significativamente sobre la densidad o el grosor de la cicatriz postoperatoria. Sin embargo, el hecho de que este material es bien tolerado, siendo sustituido por tejido fibroso, sin que se produzca una respuesta inflamatoria, sugiere que su empleo sobre el espacio epidural puede ser ventajoso respecto de otros materiales bio-reabsorbibles y apoya los resultados de estudios previos que sugieren la utilidad de las mallas de vicril como sustitutos durales.
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