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Case Report
Uncorrected Proof. Available online 1 December 2025
Myxoid glioneuronal tumor with PDGFRA p.K385 mutation: Radiological insights from two cases
Tumor glioneuronal mixoide con mutación PDGFRA p.K385: hallazgos radiológicos de dos casos
Anrong Zenga, Xiaorui Sub, Wei Hua, Qiang Yuea,c,
Corresponding author
scu_yq@163.com

Corresponding author.
a Department of Radiology, West China Hospital of Sichuan University, Chengdu, China
b Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China
c Huaxi Glioma Center, West China Hospital of Sichuan University, Chengdu, China
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Table 1. Imaging features of myxoid glioneuronal tumor.
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Abstract

Myxoid glioneuronal tumor represents a newly recognized entity in the 2021 World Health Organization classification of central nervous system tumors. As one of the 14 defined neuronal and glioneuronal tumors, it is molecularly characterized by PDGFRA p.K385 mutation. In this paper, we illustrate computed tomography, conventional and functional magnetic resonance imaging, and positron emission tomography-computed tomography imaging features of two myxoid glioneuronal tumor cases, introducing novel imaging characteristics.

Keywords:
Myxoid glioneuronal tumor
Magnetic resonance imaging
Positron emission tomography-computed tomography
Case series
Resumen

El tumor glioneuronal mixoide representa una entidad recientemente reconocida en la clasificación de 2021 de la Organización Mundial de la Salud de tumores del sistema nervioso central. Como una de las 14 neoplasias neuronales y glioneuronales definidas, se caracteriza molecularmente por la mutación PDGFRA p.K385. En este artículo, ilustramos las características de imagen de tomografía computarizada, resonancia magnética convencional y funcional y tomografía por emisión de positrones-computarizada en dos casos de tumores glioneuronales mixoides, presentando características imagenológicas novedosas.

Palabras clave:
Tumor glioneuronal mixoide
Resonancia magnética
Tomografía por emisión de positrones-tomografía computarizada
Serie de casos

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