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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La presencia de formaciones tumorales m&#250;ltiples de la misma histog&#233;nesis en el interior de la cavidad craneal &#40;TMI&#41; es una situaci&#243;n bien conocida desde los puntos de vista neurorradiol&#243;gico&#44; neuroquir&#250;rgico y neuropatol&#243;gico&#46; Mucho menos frecuentes son las asociaciones tumorales intracraneales &#40;ATI&#41;&#44; es decir&#44; los cuadros constituidos por dos o m&#225;s tumores de distinta histog&#233;nesis en la cavidad craneal&#59; aproximadamente&#44; el 50&#37; de las ATI consisten en la asociaci&#243;n sincr&#243;nica o diacr&#243;nica de un meningioma y un glioblastoma multiforme&#46; Una forma especial de ATI es la que se ha denominado en la literatura tumor en colisi&#243;n &#40;ATI-C&#41;&#44; consistente en la presencia de dos tumores de distinta histog&#233;nesis topogr&#225;ficamente yuxtapuestos&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se presentan ocho enfermos&#44; con ATI y ATI-C&#44; estudiados en el Servicio de Neurocirug&#237;a del Hospital Universitario &#8220;12 de Octubre&#8221;&#59; admitidos entre 1976 y 1998&#46; Se destacan las dificultades diagn&#243;sticas en los primeros casos antes de la introducci&#243;n de los nuevos m&#233;todos de neuroimagen&#46; Asimismo&#44; se considera que las discrepancias entre distintas exploraciones radiol&#243;gicas&#44; quir&#250;rgicas y quir&#250;rgico-evolutivas deben hacer pensar en la posibilidad de ATI&#46; En &#250;ltima instancia&#44; se revisa la literatura m&#233;dica pertinente a las ATI y las ATI-C&#46;</p>"
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Vol. 11. Núm. 1.
Páginas 31-42 (enero 1999)
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Vol. 11. Núm. 1.
Páginas 31-42 (enero 1999)
Asociaciones tumorales en el sistema nervioso central. Estudio de ocho casos con verificación quirúrgica
Multiple tumors of the Nervous System. Analysis of eight surgically verified cases of association of intracranial tumors
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S. Castro, R. Díez Lobato, S. Madero, R. Alday, A. Cabrera, P. González León, J.R. Ricoy, E. Lamas
Servicio de Neurocirugía y Sección de Neuropatología. Hospital Universitario 12 de Octubre. Madrid
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La presencia de formaciones tumorales múltiples de la misma histogénesis en el interior de la cavidad craneal (TMI) es una situación bien conocida desde los puntos de vista neurorradiológico, neuroquirúrgico y neuropatológico. Mucho menos frecuentes son las asociaciones tumorales intracraneales (ATI), es decir, los cuadros constituidos por dos o más tumores de distinta histogénesis en la cavidad craneal; aproximadamente, el 50% de las ATI consisten en la asociación sincrónica o diacrónica de un meningioma y un glioblastoma multiforme. Una forma especial de ATI es la que se ha denominado en la literatura tumor en colisión (ATI-C), consistente en la presencia de dos tumores de distinta histogénesis topográficamente yuxtapuestos.

Se presentan ocho enfermos, con ATI y ATI-C, estudiados en el Servicio de Neurocirugía del Hospital Universitario “12 de Octubre”; admitidos entre 1976 y 1998. Se destacan las dificultades diagnósticas en los primeros casos antes de la introducción de los nuevos métodos de neuroimagen. Asimismo, se considera que las discrepancias entre distintas exploraciones radiológicas, quirúrgicas y quirúrgico-evolutivas deben hacer pensar en la posibilidad de ATI. En última instancia, se revisa la literatura médica pertinente a las ATI y las ATI-C.

Palabras clave:
Tumores cerebrales múltiples
Asociación tumoral
Tumores en colisión
Summary

Multiple primary brain tumors may occur in the setting of neurofibromatosis but the simultaneous occurrence of two neoplasms, without predisposing factors, is much less frequent.

We present eight patients studied at our Service between 1976 to 1998, who had such dual tumoral association. We emphasize the diagnostic difficulties found in the cases admitted before the advent of Computerized Tomography and Magnetic Resonance. Even with the new neuroimaging studies, discrepancies between clinico-radiologic, intraoperative and postoperative findings should led to the suspicion of tumor association. Tumoral associations reported in the literature are commented.

Key words:
Multiple intracranial tumor
Association Tumor
Collision Tumor

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