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Case Report
Uncorrected Proof. Available online 25 November 2024
Cord compression due to atypical T-cell lymphoma from paraspinal soft tissue: Report of a case
Compresión medular debida a linfoma T atípico de tejidos blandos paraespinales: caso clínico
Alejandro Augusto Ortega Rodriguez
Corresponding author
aaortega.girona.ics@gencat.cat

Corresponding author.
, Santiago Nicolás Valbuena Dussan, José Luís Caro Cardera, Jordi de Manuel-Rimbau Muñoz
Department of Neurosurgery, Hospital Universitari de Girona Doctor Josep Trueta, Girona, Girona, Spain
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Abstract

During lymphoma’s natural history of disease, 5–10% of cases may develop Central Nervous affectation. We present the case of a 57-years-old man with less than 24 h of onset symptoms of paraparesis, lower limb hypoesthesia and sphincter dysfunction who was operated due to dorsal tumor with epidural component which caused severe cord compression. Pathological analysis concluded atypical T-cell lymphoblastic lymphoma, a rare subtype of lymphoma which accounts 1%−2% of all Non-Hodgkin Lymphomas. Our case was particularly aggressive and atypical due to its origin in paraspinal soft tissue. Despite specific treatment, the patient presented an early epidural relapse, frequent in this lymphoma subtype.

Keywords:
Lymphoma
Paraparesis
Surgery
T-cell
Resumen

Durante la historia natural del linfoma, entre el 5 y el 10% de los casos pueden desarrollar afectación del Sistema Nervioso Central. Se presenta el caso de un varón de 57 años con menos de 24 horas de inicio de síntomas de paraparesia, hipoestesia de miembros inferiores y disfunción de esfínteres quien fue intervenido de un tumor dorsal con componente epidural que provocaba compresión medular severa. El informe anatomo-patológico concluyó que se trataba de un linfoma linfoblástico de células T atípico, un subtipo raro de linfoma que representa entre el 1% y el 2% de todos los linfomas no Hodgkin. Nuestro caso fue particularmente agresivo y atípico por su origen en tejidos blandos paraespinales. A pesar del tratamiento específico, el paciente presentó una recidiva epidural precoz, frecuente en este subtipo de linfoma.

Palabras clave:
Célula T
Cirugía
Linfoma
Paraparesia

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