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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">En pacientes con acromegalia&#44; los efectos pleiotr&#243;picos de la GH e IGF-1 se han asociado con el desarrollo de disfunci&#243;n endotelial y anomal&#237;as vasculares&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se presenta el caso de un var&#243;n de 45 a&#241;os con diagn&#243;stico de acromegalia&#46; La resonancia magn&#233;tica identific&#243; una marcada dilataci&#243;n de ambas arterias car&#243;tidas internas &#40;ACI&#41; cavernosas con medializaci&#243;n de las mismas condicionando una distancia intercarot&#237;dea estrecha&#44; fen&#243;meno conocido como &#8220;kissing car&#243;tidas&#8221;&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Esta alteraci&#243;n vascular se ha descrito en mayor proporci&#243;n en pacientes con acromegalia&#46; Las anomal&#237;as que tambi&#233;n se presentan con mayor prevalencia en estos pacientes son&#58; aneurismas de la ACI&#44; protusi&#243;n de la ACI en el seno esfenoidal&#44; distancia intercarot&#237;dea estrecha&#44; dilataci&#243;n fusiforme de la ACI y la dehiscencia de tal arteria en el canal &#243;seo&#46; La presencial de tales alteraciones&#44; aumenta el riesgo de lesi&#243;n de la ACI&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">La detecci&#243;n prequir&#250;rgica de tales alteraciones es fundamental para garantizar la seguridad del abordaje quir&#250;rgico&#46;</p></span>"
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Case Report
Pre-proof, online 29 October 2024
Endothelial dysfunction and vascular abnormalities in acromegaly. A case report
Disfunción endotelial y anomalías vasculares en acromegalia. A propósito de un caso
Ana Irigaray Echarria,
Corresponding author
anairigarayecharri@gmail.com

Corresponding author.
, M. Dolores Ollero García-Agullóa, José Jorge Ortez Torob, Idoya Zazpe Cenozc
a Servicio de Endocrinología y Nutrición, Hospital Universitario de Navarra, Pamplona, Navarra, Spain
b Sección de Endocrinología y Nutrición, Hospital Reina Sofía, Tudela, Navarra, Spain
c Servicio de Neurocirugía, Hospital Universitario de Navarra, Pamplona, Navarra, Spain

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